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LUCIGENIN

LUCIGENIN structure

CAS No.: 2315-97-1

Chemical Name:: LUCIGENIN

Synonyms: L-6868;LUCIGENIN;NSC-151912;Lucigenine;Lucigenin Nitrate;Lucigenin, HPLC 99%;LUCIGENIN USP/EP/BP;9,9'-Bi(10-methylacridinium);9,9'-Bi[10-methylacridinium];BIS(N-METHYLACRIDINIUM) NITRATE

CBNumber:: CB3325847

Molecular Formula:: C28H22N4O6

Molecular Weight:: 510.5

MDL Number:: MFCD00011925

MOL File:: 2315-97-1.mol

Last updated:2023-11-10 11:46:24

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LUCIGENIN Properties

Melting point	250°C
solubility	acetic acid: soluble10mg/mL
form	powder
color	Yellow powder with orange to brown cast
λmax	455nm
BRN	3901768
Biological Applications	Chloride indicator; diagnosis of hemostatic disorders; detecting bacteria,nucleicacids,proteins,pathogens; identifying respiratory infections; generating and detecting reactive oxygen species; chemiluminescent indicator
InChI	InChI=1S/C28H22N2.2NO3/c1-29-23-15-7-3-11-19(23)27(20-12-4-8-16-24(20)29)28-21-13-5-9-17-25(21)30(2)26-18-10-6-14-22(26)28;22-1(3)4/h3-18H,1-2H3;;/q+2;2-1
InChIKey	KNJDBYZZKAZQNG-UHFFFAOYSA-N
SMILES	C1(=C2C=CC=CC2=[N+](C)C2=CC=CC=C12)C1=C2C=CC=CC2=[N+](C)C2=CC=CC=C12.[N+]([O-])([O-])=O.[N+]([O-])([O-])=O

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS03,GHS07

Signal word

Warning

Hazard statements

H272-H315-H319

Precautionary statements

P210-P220-P221-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P501

Safety Statements

24/25

RIDADR

1479

WGK Germany

HazardClass

5.1

PackingGroup

III

HS Code

29339900

NFPA 704

	0
2		0

LUCIGENIN price More Price(31)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	M8010	N,N′-Dimethyl-9,9′-biacridinium dinitrate used as chemiluminescent reagent	2315-97-1	1g	$403	2024-03-01	Buy
Sigma-Aldrich	M8010	N,N′-Dimethyl-9,9′-biacridinium dinitrate used as chemiluminescent reagent	2315-97-1	5g	$1300	2024-03-01	Buy
TCI Chemical	B1203	10,10'-Dimethyl-9,9'-biacridinium Dinitrate [for Chemiluminescence Research] >97.0%(HPLC)	2315-97-1	1g	$170	2024-03-01	Buy
TCI Chemical	B1203	10,10'-Dimethyl-9,9'-biacridinium Dinitrate [for Chemiluminescence Research] >97.0%(HPLC)	2315-97-1	5g	$511	2024-03-01	Buy
Cayman Chemical	14872	Lucigenin ≥95%	2315-97-1	50mg	$32	2024-03-01	Buy

Product number	Packaging	Price	Buy
M8010	1g	$403	Buy
M8010	5g	$1300	Buy
B1203	1g	$170	Buy
B1203	5g	$511	Buy
14872	50mg	$32	Buy

LUCIGENIN Chemical Properties,Uses,Production

Description

Lucigenin is a chemiluminescent probe used to detect superoxide production and the presence of chloride. It can be used to detect superoxide production by enzymatic and cellular sources. It is a sensitive method that has been applied to the monitoring of superoxide production from xanthine oxidase, microsomal NADPH cytochrome reductase, and NADPH oxidases of phagocytes, endothelial cells, fibroblasts, and smooth muscle cells of blood vessel walls. However, it produces similar chemiluminescence signals in isolated aortic and cardiac tissues from wild-type and Nox1-Nox2-Nox4 triple knockout mice, suggesting that it is not selective for NADPH-based ROS production. It also reacts with hydrogen peroxide without generating free radical intermediates and has been used to detect lipid hydroperoxide in oils. Lucigenin is also used as a fluorescent chloride-sensitive indicator, with its fluorescence being quenched by chloride (ex/em = 455/505 nm, respectively). Lucigenin fluorescence is insensitive to phosphate, sulfate, and nitrate.

Chemical Properties

Dark yellow powder

Uses

Chemiluminescent probe for the detection of peroxides in biological systems.

Uses

Lucigenine, is used as chemiluminescence. It exhibits a bluish-green fluorescence. Dyes and metabolites.

Mechanism of action

In the case of lucigenin it is first reduced to a cation radical. Then it reacts in its univalently reduced form with ROS to produce dioxetane, which breaks down to generate photons. These probes cannot measure the individual free radicals but measure global ROS levels in the sample. Luminescence signals are expressed in relative light units (RLU), a direct measure of free radicals produced.

LUCIGENIN Preparation Products And Raw materials

Raw materials

Preparation Products

LUCIGENIN Suppliers

Global( 157)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Zhengzhou Lingzhiyue Technology Co., Ltd	+86-0371-55074660 +86-13783527580	Lingzhiyue@aliyun.com	China	3141	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Zhengzhou Yuanli Biological Technology Co., Ltd	0086-371-67897895	info@zzyuanli.cn	CHINA	136	58
Changzhou Ansciep Chemical Co., Ltd.	+86 519 86305871	sales@ansciepchem.com	CHINA	4242	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
Zhengzhou Alfa Chemical Co.,Ltd	+8618530059196	sale04@alfachem.cn	China	12527	58
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12456	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58

Supplier	Advantage
Zhengzhou Lingzhiyue Technology Co., Ltd	58
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Zhengzhou Yuanli Biological Technology Co., Ltd	58
Changzhou Ansciep Chemical Co., Ltd.	58
Hubei Jusheng Technology Co.,Ltd.	58
Chongqing Chemdad Co., Ltd	58
Zhengzhou Alfa Chemical Co.,Ltd	58
Hebei Mojin Biotechnology Co., Ltd	58
TargetMol Chemicals Inc.	58

View Lastest Price from LUCIGENIN manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-02	N,N'-Dimethyl-9,9'-bisacridinium nitrate 2315-97-1	US $0.00 / g	5g	>99.00%	5g	Xian confluore Biological Technology Co., Ltd.
2023-01-31	LUCIGENIN 2315-97-1	US $100.00 / kg/drum	1kg/drum	>95%	5000kg	Hebei Mojin Biotechnology Co., Ltd
2019-07-06	LUCIGENIN 2315-97-1	US $1.00 / KG	1g	99%	100KG	Career Henan Chemical Co

N,N'-Dimethyl-9,9'-bisacridinium nitrate
2315-97-1
US $0.00 / g
>99.00%
Xian confluore Biological Technology Co., Ltd.

LUCIGENIN
2315-97-1
US $100.00 / kg/drum
>95%
Hebei Mojin Biotechnology Co., Ltd

LUCIGENIN
2315-97-1
US $1.00 / KG
99%
Career Henan Chemical Co

LUCIGENIN Spectrum

LUCIGENIN(2315-97-1)MS LUCIGENIN(2315-97-1)IR1 LUCIGENIN(2315-97-1)IR2

2315-97-1(LUCIGENIN)Related Search:

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LUCIGENIN(RG) LUCIGENIN(REAGENT / STANDARD GRADE) Lucigenin [Bis-N-methylacridinium nitrate] *UltraPure Grade* LUCIGENIN [BIS-N-METHYLACRIDINIUM NITRATE]

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lucigenin or N,N′-dimethyl-9,9′-biacridinium dinitrate L-6868 NSC-151912 9,9'-BIS(N-METHYLACRIDINIUM NITRATE) LUCIGENIN 10,10'-Dimethyl-9,9'-biacridinium Dinitrate [for Chemiluminescence Research] BIS(N-METHYLACRIDINIUM) DINITRATE BIS(N-METHYLACRIDINIUM) NITRATE N,N'-DIMETHYL-9,9'-BIACRIDINIUM DINITRATE N,N'-DIMETHYL-9,9'-BIACRIDINIUM NITRATE N,N'-DIMETHYLBISACRIDINIUM DINITRATE 10,10’-dimethyl-9,9’-biacridinium N,N-dimethyl-9,9-bisacridinium nitrate N,N'-DIMETHYL-9,9'-BIACRIDINIUM- BIS-N-METHYLACRIDINIUM NITRATE 97% Lucigenin, HPLC 99% BIS(N-METHYLACRIDINUIM) DINATRATE 9,9μ-Bis(N-methylacridinium nitrate), Lucigenin 10,10'-Dimethyl-9,9'-biacridine-10,10'-diium·2nitrate Lucigenine 10,10'-Dimethyl-9,9'-biacridine-10,10'-diium 9,9'-Bi(10-methylacridinium) 9,9'-Bi[10-methylacridinium] 10,100-dimethyl-9,90-biacridinium Dinitrate N,n0-dimethyl-9,90-biacridinium Dinitrate 9,90biacridinium, 10,100-dimethyl-, Dinitrate 9,90-bis(nmethylacridinium Nitrate) Lucigenin Nitrate Bis(N-methylacridinium) Nitrate [for Chemiluminescence Research] 10-methyl-9-(10-methylacridin-10-ium-9-yl)acridin-10-ium,dinitrate N,N'-Dimethyl-9,9'-biacridinium dinitrate, ≥97.0% Bis(N-methylacridinium) Nitrate [for Chemiluminescence Research]> N,N'-Dimethyl-9,9'-biacridinium dinitrat LUCIGENIN USP/EP/BP N,N′-Dimethyl-9,9′-biacridinium dinitrate, ≥98% 9,9'-Biacridinium, 10,10'-dimethyl-, nitrate (1:2) 2315-97-1 C28H22N22NO3 C28H22N4O6 C28H222N2O3 BioChemical Biochemicals and Reagents Detection Fluorescent Probes, Labels, Particles and Stains Acridinium (Chemiluminescence) Chemiluminescence Miscellaneous Natural Products Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts Acridinium (Chemiluminescence) Acridine Analytical Chemistry Chemiluminescence