Isoxazole
- CAS No.
- 288-14-2
- Chemical Name:
- Isoxazole
- Synonyms
- ISOXAZOLE;Isooxazole;Isoxazolec;1,2-Oxazole;Isoxazole>Isoxazole,99%;Isoxazole 99%;ISOXAZOLE 98+%;Isoxazole, 98.5%;Different oxazole
- CBNumber:
- CB3485864
- Molecular Formula:
- C3H3NO
- Molecular Weight:
- 69.06
- MDL Number:
- MFCD00003149
- MOL File:
- 288-14-2.mol
- MSDS File:
- SDS
Melting point | -67.1°C |
---|---|
Boiling point | 93-95 °C(lit.) |
Density | 1.078 g/mL at 25 °C(lit.) |
vapor density | 2.4 (vs air) |
refractive index |
n |
Flash point | 48 °F |
storage temp. | 2-8°C |
solubility | 167g/l |
pka | -2.0(at 25℃) |
form | clear liquid |
color | Colorless to Light yellow |
BRN | 103773 |
InChIKey | CTAPFRYPJLPFDF-UHFFFAOYSA-N |
CAS DataBase Reference | 288-14-2(CAS DataBase Reference) |
FDA UNII | 00SRW0M6PW |
NIST Chemistry Reference | Isoxazole(288-14-2) |
EPA Substance Registry System | Isoxazole (288-14-2) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS02 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Danger | |||||||||
Hazard statements | H225 | |||||||||
Precautionary statements | P210 | |||||||||
Hazard Codes | F,Xi | |||||||||
Risk Statements | 11 | |||||||||
Safety Statements | 16-23/33-33-29-7/9 | |||||||||
RIDADR | UN 1993 3/PG 2 | |||||||||
WGK Germany | 3 | |||||||||
F | 10 | |||||||||
Hazard Note | Highly Flammable | |||||||||
TSCA | Yes | |||||||||
HazardClass | 3 | |||||||||
PackingGroup | II | |||||||||
HS Code | 29349990 | |||||||||
NFPA 704 |
|
Isoxazole price More Price(18)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 151637 | Isoxazole 99% | 288-14-2 | 5g | $34.9 | 2024-03-01 | Buy |
Sigma-Aldrich | 151637 | Isoxazole 99% | 288-14-2 | 25g | $113 | 2024-03-01 | Buy |
TCI Chemical | I0372 | Isoxazole >95.0%(GC) | 288-14-2 | 5g | $32 | 2024-03-01 | Buy |
Alfa Aesar | L01607 | Isoxazole, 99% | 288-14-2 | 5g | $26.65 | 2024-03-01 | Buy |
TRC | I779145 | Isoxazole | 288-14-2 | 100mg | $60 | 2021-12-16 | Buy |
Isoxazole Chemical Properties,Uses,Production
Description
Isoxazole, an important class of heterocycles, is a five membered heterocyclic compound that exhibits various pharmacological actions. It is present in some natural products such as ibotenic acid and is also used as a foundation for several drugs such as the COX-2 inhibitor valdecoxib and anti-inflammatory drugs. Isoxazoles are largely applied in the area of pharmaceuticals and therapeutics, including insecticidal, antibacterial, antibiotic, antitumour, antifungal, antituberculosis, anticancer and ulcerogenic. Besides, it has a great effect on reducing blood glucose, eliminating pain, resisting inflammation, killing harmful bacteria, controlling and reducing the risk of HIV.
Chemical Properties
A colorless liquid resembling pyridine. It is soluble in water at room temperature up to six times its volume.
Uses
Natural insecticide.
Definition
ChEBI: Isoxazole is a monocyclic heteroarene with a structure consisting of a 5-membered ring containing three carbon atoms and an oxygen and nitrogen atom adjacent to each other. It is the parent of the class of isoxazoles. It is a mancude organic heteromonocyclic parent, a monocyclic heteroarene and a member of isoxazoles.
Preparation
Isoxazoles can be synthesized by various methods, such as the 1,3-dipolar cycloaddition reaction of nitrile oxides with alkynes, the reaction of hydroxylamine with 1,3-diketones or propiolic acid derivatives, etc.
www.organic-chemistry.org
General Description
Isoxazole(288-14-2) are described as inhibitors of acetylcholinesterase (AChE). Isoxazole ligands bind to and inhibit the Sxc- antiporter.
Hazard
Narcotic and psychomimetic effects.
References
https://en.wikipedia.org/wiki/Isoxazole
https://pubchem.ncbi.nlm.nih.gov/compound/9254
Isoxazole Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29888 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49392 | 58 |
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21149 | 58 |
Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10326 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34571 | 58 |
HONG KONG IPURE BIOLOGY CO.,LIMITED | 86 18062405514 18062405514 | ada@ipurechemical.com | CHINA | 3465 | 58 |
Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14350 | 58 |
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