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3-Nitrophenol

CAS No.554-84-7
Chemical Name:3-Nitrophenol
Synonyms:m-Nitrofenol;3-nitro-pheno;M-NITROPHENOL;3-NITROPHENOL;m-nitro-pheno;Phenol,3-nitro-;meta-Nitrophenol;Phenol, m-nitro-;m-nitrophenol[qr];3-NitrophenolA.R.
CBNumber:CB3728637
Molecular Formula:C6H5NO3
Formula Weight:139.11
MOL File:554-84-7.mol
3-Nitrophenol Property
mp : 89-95 °C
bp : 194 °C70 mm Hg(lit.)
density : 1,49 g/cm3
Fp : 102°C
Water Solubility : 13.5 g/L (25 ºC)
Merck : 14,6619
BRN : 1907946
CAS DataBase Reference: 554-84-7(CAS DataBase Reference)
NIST Chemistry Reference: Phenol, 3-nitro-(554-84-7)
EPA Substance Registry System: Phenol, 3-nitro-(554-84-7)
Safety
Hazard Codes : Xn,Xi
Risk Statements : 22-38-41-36/37/38-33-20/21/22
Safety Statements : 26-36/37-45-36/37/39-22-28
RIDADR : UN 1663 6.1/PG 3
WGK Germany : 3
RTECS : SM1925000
F : 8
Hazard Note : Harmful/Irritant
HazardClass : 6.1
PackingGroup : III
HS Code : 29089000
Hazardous Substances Data: 554-84-7(Hazardous Substances Data)

3-Nitrophenol Chemical Properties,Usage,Production

Chemical Properties
yellow to brown crystalline powder
Usage
3-Nitrophenol is a chemical reagent used in various organic syntheses. Used in the synthesis of RAGE inhibitors via the etherification of phenols. Also used in the synthesis of kinase inhibitors again st epidermal growth factor receptor T790M mutation.
General Description
Colorless to pale yellow crystalline solid. Sinks in and mixes with water.
Air & Water Reactions
Water insoluble.
Reactivity Profile
3-Nitrophenol is a light-yellow, crystalline material, toxic and irritant. When heated to decomposition 3-Nitrophenol emits toxic fumes of oxides of nitrogen [Lewis, 3rd ed., 1993, p. 941]. Phenols do not behave as organic alcohols, as one might guess from the presence of a hydroxyl (-OH) group in their structure. Instead, they react as weak organic acids. Phenols and cresols are much weaker as acids than common carboxylic acids (phenol has Ka = 1.3 x 10^[-10]). These materials are incompatible with strong reducing substances such as hydrides, nitrides, alkali metals, and sulfides. Flammable gas (H2) is often generated, and the heat of the reaction may ignite the gas. Heat is also generated by the acid-base reaction between phenols and bases.
Health Hazard
INHALATION: Inhalation or ingestion causes headaches, drowsiness, nausea, and blue color in lips, ears, and finger nails (cyanosis). EYES: Contact with eyes causes irritation. SKIN: Can be absorbed through intact skin to give same symptoms as for inhalation.
Fire Hazard
Special Hazards of Combustion Products: Dangerous toxic fumes of NO x
3-Nitrophenol Preparation Products And Raw materials
Raw materials
3-Nitroaniline
Preparation Products
m-Anisidine 2,5-DINITROPHENOL 3,5-DINITROPHENOL
3-Nitrophenol Suppliers      Global( 141)Suppliers     
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Hangzhou Disynthesis Chemical Technology Co., Ltd. +86 (571) 8819-4596/ 15558156576,18006812693 QQ:1695750899+86 (571) 8819-9298sales@disynchem.com;sales1@disynchem.comCHINA 290 55
Shanghai Boyle Chemical Co., Ltd. Mr Qiu:021-50182298;Ms Xu:+86-21-50180596;Miss Zhang:021-50185988+86-21-57758967sales@boylechem.comCHINA 10054 55
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833+86-10-82849933jkinfo@jkchemical.com;market3@jkchemical.comCHINA 96869 76
Meryer (Shanghai) Chemical Technology Co., Ltd. +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-62670440(Beijing)+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-62670790(Beijing)sh@meryer.com; sz@meryer.comCHINA 40414 62
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