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2-Cyclopenten-1-one

CAS No.
930-30-3
Chemical Name:
2-Cyclopenten-1-one
Synonyms
2-CYCLOPENTEN-1-ONE;Cyclopentenone;CYCLOPENT-2-ENONE;2-CYCLOPENTENE-1-ONE;CPEO;2-CycL;NSC 73117;openten-1-one;2-CYCLOPENTENONE;cyclopenten-2-one
CBNumber:
CB3744099
Molecular Formula:
C5H6O
Molecular Weight:
82.1
MDL Number:
MFCD00001401
MOL File:
930-30-3.mol
MSDS File:
SDS
Last updated:2024-08-02 09:53:02

2-Cyclopenten-1-one Properties

Boiling point 64-65 °C19 mm Hg(lit.)
Density 0.98 g/mL at 25 °C(lit.)
refractive index n20/D 1.481(lit.)
Flash point 108 °F
storage temp. 2-8°C
solubility soluble in Chloroform, Methanol
form Liquid
color Clear yellow
Specific Gravity 0.980
Water Solubility almost insoluble
BRN 1446054
InChI InChI=1S/C5H6O/c6-5-3-1-2-4-5/h1,3H,2,4H2
InChIKey BZKFMUIJRXWWQK-UHFFFAOYSA-N
SMILES C1(=O)CCC=C1
LogP -0.114 (est)
CAS DataBase Reference 930-30-3(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII Q0U2IGF9CK
NIST Chemistry Reference 2-Cyclopenten-1-one(930-30-3)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07
Signal word  Warning
Hazard statements  H335-H226
Precautionary statements  P261-P280a-P405-P501a-P210-P233-P240-P241+P242+P243-P280-P303+P361+P353-P370+P378-P403+P235-P501
Hazard Codes  Xi,Xn
Risk Statements  10-37-36/37/38-22
Safety Statements  16-36-36/37/39
RIDADR  UN 1224 3/PG 3
WGK Germany  3
8
Hazard Note  Irritant
HazardClass  3
PackingGroup  III
HS Code  29142990
NFPA 704
2
2 0

2-Cyclopenten-1-one price More Price(35)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C112909 2-Cyclopenten-1-one 98% 930-30-3 5g $82.1 2024-03-01 Buy
Sigma-Aldrich C112909 2-Cyclopenten-1-one 98% 930-30-3 25g $195 2024-03-01 Buy
TCI Chemical C0794 2-Cyclopenten-1-one >96.0%(GC) 930-30-3 5mL $57 2024-03-01 Buy
TCI Chemical C0794 2-Cyclopenten-1-one >96.0%(GC) 930-30-3 25mL $198 2024-03-01 Buy
Alfa Aesar B23408 2-Cyclopenten-1-one, 98% 930-30-3 5g $74.5 2024-03-01 Buy
Product number Packaging Price Buy
C112909 5g $82.1 Buy
C112909 25g $195 Buy
C0794 5mL $57 Buy
C0794 25mL $198 Buy
B23408 5g $74.5 Buy

2-Cyclopenten-1-one Chemical Properties,Uses,Production

Description

2-Cyclopentenone contains two functional groups, a ketone and an alkene. It is a colourless liquid. 2-cyclopenten-1-one selectively induces the expression of the 70-kDa HSP (HSP70) in human cells through cycloheximide-sensitive activation of heat shock transcription factor 1 (HSF1). It is a natural product found in Perilla frutescens[1].

Chemical Properties

clear yellow liquid

Uses

2-Cyclopenten-1-one is a versatile electrophile employed in various addition reactions including conjugate addition of organocopper nucleophiles, Michael reaction with silyl enol ethers and siloxanes. It is also used in Diels-Alder cycloadditions and phosphoniosilylations.

Definition

ChEBI: 2-cyclopenten-1-one is an enone that is cyclopentanone having a C=C double bond at position 2. It has a role as a Hsp70 inducer. It is an enone and an alicyclic ketone.

Preparation

2-Cyclopentenones can be synthesized in a number of ways. One of the routes involves elimination of α-bromo-cyclopentanone using lithium carbonate and Claisen condensation-decarboxylation-isomerization cascades of unsaturated diesters as shown below.
Synthesis of 2-Cyclopenten-1-one
The acid-catalyzed dehydration of cyclopentanediols affords cyclopentenone.
As a functional group, the synthesis of 2-cyclopentenones is accomplished in a variety of other ways, including the Nazarov cyclization reaction from divinyl ketones, Saegusa–Ito oxidation from cyclopentanones, ring-closing metathesis from the corresponding dienes, oxidation of the corresponding cyclic allylic alcohols, and the Pauson–Khand reaction from alkenes, alkynes, and carbon monoxide.
en.wikipedia.org

References

[1] A Rossi, M G Santoro, G Elia. “2-Cyclopenten-1-one, a new inducer of heat shock protein 70 with antiviral activity.” The Journal of Biological Chemistry 271 50 (1996): 32192–6.

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View Lastest Price from 2-Cyclopenten-1-one manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Cyclopentenone pictures 2023-12-04 2-Cyclopentenone
930-30-3
US $0.00-0.00 / kg 0.10000000149011612kg 98% 100kg Huida Pharmaceutical Technology (Shanghai) Co., Ltd.
2-Cyclopentenone pictures 2023-12-04 2-Cyclopentenone
930-30-3
US $0.00-0.00 / kg 0.10000000149011612kg 98% 100kg Huida Pharmaceutical Technology (Shanghai) Co., Ltd.
2-Cyclopentenone pictures 2022-02-22 2-Cyclopentenone
930-30-3
US $0.00 / KG 1KG 97.9% 100 tons Honest Joy Holdings Limited
  • 2-Cyclopentenone pictures
  • 2-Cyclopentenone
    930-30-3
  • US $0.00-0.00 / kg
  • 98%
  • Huida Pharmaceutical Technology (Shanghai) Co., Ltd.
  • 2-Cyclopentenone pictures
  • 2-Cyclopentenone
    930-30-3
  • US $0.00-0.00 / kg
  • 98%
  • Huida Pharmaceutical Technology (Shanghai) Co., Ltd.
2-CYCLOPENTENONE CPEO 2_cyclopenten-1-0ne 2-cyclopenten-1-0ne 2-Cyclopentenone-1 3-Cyclopenten-2-one Cyclopenten-3-one cyclopenten-2-one 2-Cyclopentenone, pure, 98% Cyclopent-2-en-1-one 97% 1-Cyclopenten-3-one 2-Cyclopentenone, 98%, pure Cyclopent-2-en-3-one 2-Cyclopenten-1-one ,96% 1-Oxocyclopent-2-ene, Cyclopent-1-en-3-one 2-Cyclopentenone, pure, 98% 25GR 2-Cyclopentenone, pure, 98% 5GR 2-Cyclopenten-1-one, 97+% 3-Oxocyclopent-1-ene, Cyclopent-1-en-3-one Cyclopent-2-en-1-one 98+% 2-CycL openten-1-one 2-Cyclopenten-1-one > 2-Cyclopenten-1-one, 96%, for synthesis 2-Cyclopenten-1-One,>98% 1-CYCLOPENTEN-5-ONE NSC 73117 2-CYCLOPENTEN-1-ONE 2-CYCLOPENTENE-1-ONE CYCLOPENT-2-ENONE Cyclopentenone 2-Cyclopenten-1-one (6CI, 7CI, 8CI, 9CI, ACI) 930-30-3 C5H6O Building Blocks Carbonyl Compounds C3 to C6 Organic Building Blocks Ketones Ring Systems C3 to C6 Carbonyl Compounds Ketones Pyridines