Thymosin beta 4
- CAS No.
- 77591-33-4
- Chemical Name:
- Thymosin beta 4
- Synonyms
- Thymosin β4;Thymosin β4 Acetate;Thymosin β4 Acetate;Thymosin beta4;TB500（Thymosin beta-4）;AC-SER-ASP-LYS-PRO-ASP-MET-ALA-GLU-ILE-GLU-LYS-PHE-ASP-LYS-SER-LYS-LEU-LYS-LYS-THR-GLU-THR-GLN-GLU-LYS-ASN-PRO-LEU-PRO-SER-LYS-GLU-THR-ILE-GLU-GLN-GLU-LYS-GLN-ALA-GLY-GLU-SER-OH;Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser-OH acetate salt;Tb4;TB500(5MG);Thymosin-b4
- CBNumber:
- CB4409683
- Molecular Formula:
- C212H350N56O78S
- Molecular Weight:
- 4963.4408
- MDL Number:
- MFCD00082073
- MOL File:
- 77591-33-4.mol
- MSDS File:
- SDS
| storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
|---|---|
| Water Solubility | Water : 50 mg/mL?(10.07 mM;?Need ultrasonic) |
| InChIKey | UGPMCIBIHRSCBV-XNBOLLIBSA-N |
| FDA UNII | 2D5MRE3SSY |
Thymosin beta 4 price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 157005 | Thymosin Beta 4 | 77591-33-4 | 10ug | $327 | 2021-12-16 | Buy |
| Usbiological | 157004 | Thymosin Beta 4 | 77591-33-4 | 10ug | $327 | 2021-12-16 | Buy |
| Usbiological | 157001 | Thymosin Beta 4 | 77591-33-4 | 10ug | $333 | 2021-12-16 | Buy |
| Usbiological | 157002 | Thymosin Beta 4 | 77591-33-4 | 10ug | $343 | 2021-12-16 | Buy |
| Usbiological | T5225-05B | Thymosin, beta 4 | 77591-33-4 | 1mg | $375 | 2021-12-16 | Buy |
Thymosin beta 4 Chemical Properties,Uses,Production
Description
Thymosin β-4 is an endogenous pro-angiogenic, fibroblast-activating peptide that is involved in hormone regulation. Thymosin β-4 also exhibits immunomodulatory and cardioprotective activities. Thymosin β-4 improves would healing in cardiac issue and improves cardiac function in vivo. Thymosin β-4 binds G-actin filaments, preventing actin polymerization.
benefits
Thymosin Beta-4 is a 43-amino-acid peptide that promotes healing throughout the body. It also has anti-inflammatory properties. Found naturally in higher concentrations at injury sites, the water-soluble protein can repair tissue damage and regulate cell migration to a site. It can improve wound healing and repair not only the skin, but also the brain, spinal cord, and heart. Medical professionals consider Thymosin Beta-4 a safe and powerful substance in its natural or synthetic form known as TB-500.
In addition, TB4 has a low molecular weight and doesn’t bind to the extracellular matrix. This enables it to easily travel throughout body tissues, which promotes a faster rate of healing. The peptide travels long distances, so it usually doesn’t have to be injected directly at the injury site. While some believe injecting it closer to an injured area yields better results, clinical evidence suggests otherwise.
Mechanism of action
Recent studies have revealed that the first gene to be upregulated after an injury is a Thymosin beta 4 gene. As the body begins the recovery process,Thymosin beta 4 aids in the creation of new vessels in the injured area, which carry blood, nutrients, and reparative substances to the site. It also has anti-inflammatory properties and works to decrease the amount of inflammatory substances, called cytokines. Inflammation plays a large role in many of the symptoms associated with a number of other conditions (i.e., Lyme disease, CFS, FM, autoimmune diseases, infections, etc.), making the potential impact of Tβ4 quite extensive.
Clinical Use
Thymosin beta 4 has been used in the treatment of HIV, AIDS, Influenza, colds, and various infections. It has been utilized in the management of various inflammatory conditions, as well as part of treatment following a heart attack due to its cardio and neuroprotective effects.
Side effects
Many studies have found that Thymosin beta 4 is a safely consumable peptide. The main side effect of Thymosin beta 4 is related to its anti-apoptotic activity, as it may promote the metastatic potential of tumor cells and enable rapid spread. Additionally, common mild side effects of this peptide include redness and discomfort at joints, and in some cases, it may even cause tiredness, lethargy, and headaches.
Thymosin beta 4 Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zhejiang Hangyu API Co., Ltd | +8617531972939 | anna@api-made.com | China | 2944 | 58 |
| Cellmano Biotech Limited | 0551-65326643 18156095617 | info@cellmano.com | China | 999 | 58 |
| Changzhou Xuanming Pharmaceutical Technology Co., Ltd. | +8618068519287 | sales@xuanmingchem.com | China | 822 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| Hebei Dangtong Import and export Co LTD | +8615632927689 | admin@hbdangtong.com | China | 991 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12456 | 58 |
| Apextide Co Ltd | +undefined15700198315 | senjie.hou@sinopep.com | China | 71 | 58 |
| Henan Tengmao Chemical Technology Co. LTD | +8615238638457 | salesvip2@hntmhg.com | China | 415 | 58 |
| Shanghai Chinqesen Biotechnology Co., Ltd. | +86-16628886292 +86-19521323435 | sales2@qschem-pharma.com | China | 46 | 58 |
| Shanghai Yunao International Trade Co., Ltd | +8617621705551 | asdf@shanghaihg.cn | China | 265 | 58 |
Related articles
- Synthesis and Applications of Thymosin Beta 4
- Thymosin β 4 not only plays a crucial role in the biological healing cascade reaction, but also plays an important role in the....
- Mar 28，2024
- Thymosin beta 4 acetate: mechanism of action and activities
- Thymosin beta 4 acetate promotes tissue repair, angiogenesis, and has anti-inflammatory and antimicrobial properties.
- Nov 3，2023
- What is Thymosin beta 4 acetate?
- Thymosin-β4 acetate (Tβ4) is a 43 amino acid peptide which is regarded as the main intracellular G-actin sequestering peptide.....
- Jan 14，2020
Related Qustion
- Q:Does thymosin beta 4 cause cancer?
- A:Thymosin beta 4 may play an oncogenic role in NSCLC progression.
- Mar 18，2024
View Lastest Price from Thymosin beta 4 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-26 | Thymosin beta 4 acetate
77591-33-4
|
US $50.00 / g | 1g | 99% | 100kg | Wuhan Cell Pharmaceutical Co., Ltd | |
 |
2024-04-26 | TB500（Thymosin beta-4） | US $5.00-9.00 / mg | 1mg | 99% | 1000g | Wuhan Cell Pharmaceutical Co., Ltd | |
 |
2024-04-26 | Thymosin beta 4 acetate
77591-33-4
|
US $9.00-80.00 / g | 10g | min99% | 10 tons | Hebei Kangcang new material Technology Co., LTD |
-
- Thymosin beta 4 acetate
77591-33-4
- US $50.00 / g
- 99%
- Wuhan Cell Pharmaceutical Co., Ltd
-
- TB500（Thymosin beta-4）
- US $5.00-9.00 / mg
- 99%
- Wuhan Cell Pharmaceutical Co., Ltd
-
- Thymosin beta 4 acetate
77591-33-4
- US $9.00-80.00 / g
- min99%
- Hebei Kangcang new material Technology Co., LTD