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4'-AMINOPROPIOPHENONE

CAS No.
70-69-9
Chemical Name:
4'-AMINOPROPIOPHENONE
Synonyms
NSC 3187;NSC 404994;usafuctl-1856;USAF uctl-1856;4'AMINOPROPIOPHENE;4-Propanoylaniline;4-Propionylaniline;P-AMINOPROPIOPHENONE;4-AMINOPROPIOPHENONE;4’-amino-propiophenon
CBNumber:
CB4460800
Molecular Formula:
C9H11NO
Molecular Weight:
149.19
MDL Number:
MFCD00017113
MOL File:
70-69-9.mol
Last updated:2023-04-27 16:27:43

4'-AMINOPROPIOPHENONE Properties

Melting point 135-140 °C
Boiling point 270.27°C (rough estimate)
Density 1.067±0.06 g/cm3 (20 ºC 760 Torr)
refractive index 1.5279 (estimate)
storage temp. Sealed in dry,Room Temperature
pka 2.86±0.10(Predicted)
form solid
color Needles from water
Water Solubility 352.1mg/L(37.5 ºC)
CAS DataBase Reference 70-69-9(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 79GF917W6U
EPA Substance Registry System p-Aminopropiophenone (70-69-9)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H301
Precautionary statements  P301+P310
Hazard Codes  T
Risk Statements  25
Safety Statements  45-28A
RIDADR  2811
HazardClass  6.1(b)
PackingGroup  III
HS Code  29223990
Toxicity LD50 in male, female mice (mg/kg): 145, 200 i.v.; in female mice, guinea pigs, rats, male rats (mg/kg): >5000, 1020, 223.7, 475 orally (Scawin)
NFPA 704
0
2 0

4'-AMINOPROPIOPHENONE price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AK Scientific X6226 4'-Aminopropiophenone 70-69-9 250mg $26 2021-12-16 Buy
Biosynth Carbosynth FA70236 4'-Aminopropiophenone 70-69-9 1g $50 2021-12-16 Buy
Biosynth Carbosynth FA70236 4'-Aminopropiophenone 70-69-9 2g $90 2021-12-16 Buy
Activate Scientific AS145342 1-[4-(Dimethylamino)-2-hydroxyphenyl]ethan-1-one 95% 70-69-9 250mg $134 2021-12-16 Buy
Biosynth Carbosynth FA70236 4'-Aminopropiophenone 70-69-9 5G $150 2021-12-16 Buy
Product number Packaging Price Buy
X6226 250mg $26 Buy
FA70236 1g $50 Buy
FA70236 2g $90 Buy
AS145342 250mg $134 Buy
FA70236 5G $150 Buy

4'-AMINOPROPIOPHENONE Chemical Properties,Uses,Production

Description

4'-Aminopropiophenone is an oxygen-carrying molecule that has been shown to have genotoxic effects. It can be used as a control agent in toxicity studies. 4'-Aminopropiophenone also has locomotor activity in animals and affects the function of neurons. This compound has not yet been tested on humans, but it is suspected that it may have a similar effect on the human body. The analytical method for this compound is based on the spectrophotometric measurement of amines. The test for this compound is done by injecting a dose into an animal and measuring the concentration of creatinine sulfate in its blood sample over time with a spectrophotometer. Radiation can alter the shape of the molecules and change their color, so it must be kept away from this chemical during testing.

Chemical Properties

yellow-brown crystalline powder, scales

Uses

4''-Aminopropiophenone is used in method for preparing high-strength carbon nanotube film by thiol-ene click reaction.

Preparation

The preparation of 4'-aminopropiophenone is as follows:A reaction tube was charged with the 2-aryloxypropanamide (1.0 mmol), potassium hydroxide (56 mg, 1.0 mmol) and DMSO (4 mL). The mixture was heated at 140 C for 3-8 h. The reaction was monitored by TLC. After the reaction period, the reaction mixture was cooled, diluted with saturated brine and extracted with dichloromethane three times. The combined organic layers were washed with three portions of saturated brine and then dried over MgSO4 and filtered. Solvent was removed under reduced pressure. The product was purified through flash column chromatography on 300-400 mesh silica gel with petroleum ether/ethyl acetate as eluent.

70-69-9.png

General Description

Yellow needles.

Reactivity Profile

4'-AMINOPROPIOPHENONE is simultaneously a ketone and an amine. Neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Safety Profile

Poison by ingestion and intraperitoneal routes. Ingestion of large doses can cause cyanosis. A flammable liquid. When heated to decomposition it emits toxic fumes of NOx,.

Purification Methods

Crystallise it from water or aqueous EtOH. The hydrochloride has m 188-189o (aqueous EtOH/HCl drops), and the semicarbazone has m 139-140o (from EtOH/H2O). [Derrick & Bornemann J Am chem. Soc 35 1283 1913, Beilstein 14 H 59, 14 I 375, 14 III 146, 14 IV 139.]

67-56-1
100-19-6
70-69-9
99-92-3
Synthesis of 4'-AMINOPROPIOPHENONE from Methanol and 4-Nitroacetophenone

4'-AMINOPROPIOPHENONE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 124)Suppliers
Supplier Tel Email Country ProdList Advantage
Changzhou waston chemical technology Co.,Ltd
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0551-65418671 sales@tnjchem.com China 34572 58
Changzhou Helios Biomedical Science and Technology Co.,LTD.
+8618961213068 gaoxue@czhelios.com China 512 58
changzhou huayang technology co., ltd
+8615250961469 2571773637@qq.com China 9821 58

View Lastest Price from 4'-AMINOPROPIOPHENONE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4'-AMINOPROPIOPHENONE pictures 2022-10-12 4'-AMINOPROPIOPHENONE
70-69-9
US $0.00 / kg 1kg 99% According to customer requirements Changzhou waston chemical technology Co.,Ltd
4'-AMINOPROPIOPHENONE pictures 2019-07-14 4'-AMINOPROPIOPHENONE
70-69-9
US $1.00 / KG 1KG 99% 100kg Career Henan Chemical Co
P-AMINOPROPIOPHENONE P-AMINOPHENYL ETHYL KETONE NSC 3187 NSC 404994 4'-Aminopropiophenone,98% 4'-Aminopropiophenone1-(4-Aminophenyl)-1-propanone 1-(4-aminophenyl)-1-propanon 4’-amino-propiophenon Para-aminopropiophenone paraminopropiophenone Propiophenone, 4'-amino- USAF uctl-1856 usafuctl-1856 1-(4-AMINOPHENYL)-1-PROPANONE 4'-AMINOPROPIOPHENONE 4-AMINOPROPIOPHENONE Ethyl-p-aminophenyl ketone 1-Propanone, 1-(4-aminophenyl)- 4'AMINOPROPIOPHENE p-aminopropio-phenone,PAPP 4''-AMINOPROPIOPHENONE 96+% Aminopropiophenone, 4- 4-Propanoylaniline 4-Propionylaniline 4'-Aminopropiophenone hydrochloride salt 4'-Aminopropiophenonec 1-(4-(dimethylamino)-2-hydroxyphenyl)ethan-1-one 4'-AMINOPROPIOPHENONE 70-69-9 Aromatic Propiophenones (substituted)