4'-AMINOPROPIOPHENONE
|
|
4'-AMINOPROPIOPHENONE 속성
- 녹는점
- 135-140 °C
- 끓는 점
- 270.27°C (rough estimate)
- 밀도
- 1.067±0.06 g/cm3 (20 ºC 760 Torr)
- 굴절률
- 1.5279 (estimate)
- 저장 조건
- Sealed in dry,Room Temperature
- 산도 계수 (pKa)
- 2.86±0.10(Predicted)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 색상
- 물에서 결정화하여 얻은 바늘 모양의 결정
- 수용성
- 352.1mg/L(37.5℃)
- CAS 데이터베이스
- 70-69-9(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | T | ||
---|---|---|---|
위험 카페고리 넘버 | 25 | ||
안전지침서 | 45-28A | ||
유엔번호(UN No.) | 2811 | ||
위험 등급 | 6.1(b) | ||
포장분류 | III | ||
HS 번호 | 29223990 | ||
유해 물질 데이터 | 70-69-9(Hazardous Substances Data) | ||
독성 | LD50 in male, female mice (mg/kg): 145, 200 i.v.; in female mice, guinea pigs, rats, male rats (mg/kg): >5000, 1020, 223.7, 475 orally (Scawin) |
4'-AMINOPROPIOPHENONE C화학적 특성, 용도, 생산
개요
4'-Aminopropiophenone is an oxygen-carrying molecule that has been shown to have genotoxic effects. It can be used as a control agent in toxicity studies. 4'-Aminopropiophenone also has locomotor activity in animals and affects the function of neurons. This compound has not yet been tested on humans, but it is suspected that it may have a similar effect on the human body. The analytical method for this compound is based on the spectrophotometric measurement of amines. The test for this compound is done by injecting a dose into an animal and measuring the concentration of creatinine sulfate in its blood sample over time with a spectrophotometer. Radiation can alter the shape of the molecules and change their color, so it must be kept away from this chemical during testing.화학적 성질
yellow-brown crystalline powder, scales제조 방법
The preparation of 4'-aminopropiophenone is as follows:A reaction tube was charged with the 2-aryloxypropanamide (1.0 mmol), potassium hydroxide (56 mg, 1.0 mmol) and DMSO (4 mL). The mixture was heated at 140 C for 3-8 h. The reaction was monitored by TLC. After the reaction period, the reaction mixture was cooled, diluted with saturated brine and extracted with dichloromethane three times. The combined organic layers were washed with three portions of saturated brine and then dried over MgSO4 and filtered. Solvent was removed under reduced pressure. The product was purified through flash column chromatography on 300-400 mesh silica gel with petroleum ether/ethyl acetate as eluent.일반 설명
Yellow needles.반응 프로필
4'-AMINOPROPIOPHENONE is simultaneously a ketone and an amine. Neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.Safety Profile
Poison by ingestion and intraperitoneal routes. Ingestion of large doses can cause cyanosis. A flammable liquid. When heated to decomposition it emits toxic fumes of NOx,.Purification Methods
Crystallise it from water or aqueous EtOH. The hydrochloride has m 188-189o (aqueous EtOH/HCl drops), and the semicarbazone has m 139-140o (from EtOH/H2O). [Derrick & Bornemann J Am chem. Soc 35 1283 1913, Beilstein 14 H 59, 14 I 375, 14 III 146, 14 IV 139.]4'-AMINOPROPIOPHENONE 준비 용품 및 원자재
원자재
준비 용품
4'-AMINOPROPIOPHENONE 공급 업체
글로벌( 124)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Changzhou waston chemical technology Co.,Ltd | +86-051985861892 +8618112881323 |
info@wastonchem.com | China | 237 | 58 |
Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 |
product@chemlin.com.cn | CHINA | 3012 | 60 |
career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 |
sales@ansciepchem.com | CHINA | 4242 | 58 |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 |
admin@nexconn.com | China | 10248 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 |
sales@chemdad.com | China | 39916 | 58 |
Antai Fine Chemical Technology Co.,Limited | 18503026267 |
info@antaichem.com | CHINA | 9641 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 |
sales@tnjchem.com | China | 34572 | 58 |
Changzhou Helios Biomedical Science and Technology Co.,LTD. | +8618961213068 |
gaoxue@czhelios.com | China | 512 | 58 |
changzhou huayang technology co., ltd | +8615250961469 |
2571773637@qq.com | China | 9821 | 58 |
4'-AMINOPROPIOPHENONE 관련 검색:
시프로플록사신
N1-(1-OXO-2,3-DIHYDRO-1H-INDEN-5-YL)ACETAMIDE
6-Amino-3,4-dihydro-1(2H)-naphthalenone
5-Aminoindan-1-one
MEPARTRICIN
Norfloxacin
4'-AMINOPROPIOPHENONE
ETHYL 4-NITROBENZOYLACETATE
N-(5-Oxo-5,6,7,8-tetrahydronaphthalen-2-yl)acetamide
4,4'-BIS(DIMETHYLAMINO)BENZIL
3'-AMINOPROPIOPHENONE
α-Aminopropiophenone hydrochloride, S(-)-2-Amino-1-phenyl-1-propanone hydrochloride,α-aminopropiophenone hydrochloride
(-)-a-Aminopropiophenone Hydrochloride
3-DIMETHYLAMINOPROPIOPHENONE HYDROCHLORIDE
4'-MORPHOLINOPROPIOPHENONE
6-(dimethylamino)-3,4-dihydronaphthalen-1(2H)-one
4-(DIMETHYLAMINO)BENZOIN
4'-Nitro-α-(2-pyridinyl)acetophenone