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4-Chloro-1-butanol

4-Chloro-1-butanol structure

CAS No.: 928-51-8

Chemical Name:: 4-Chloro-1-butanol

Synonyms: 4-chlorobutan-1-ol;4-CHLOROBUTANOL;oro-1-butanoL;4-Chlorolbutanol;4-Choro-1-bytanol;4-CHLOROBUTANOL-1;4-Chlorbutan-1-ol;4-chloro-1-butano;4-ChIoro-1-butanoI;4-CHLORO-1-BUTANOL

CBNumber:: CB5100347

Molecular Formula:: C4H9ClO

Molecular Weight:: 108.57

MDL Number:: MFCD00002967

MOL File:: 928-51-8.mol

MSDS File:: SDS

Last updated:2024-04-25 17:59:01

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4-Chloro-1-butanol Properties

Boiling point	84-85 °C/16 mmHg (lit.)
Density	1.088 g/mL at 25 °C (lit.)
refractive index	n20/D 1.453(lit.)
Flash point	97 °F
storage temp.	2-8°C
solubility	Soluble in methanol, chloroform, and dimethyl sufoxide.
form	Liquid
pka	15.01±0.10(Predicted)
color	Clear colorless to light yellow
BRN	1731408
InChIKey	HXHGULXINZUGJX-UHFFFAOYSA-N
CAS DataBase Reference	928-51-8(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	42EI3I5AY0
NIST Chemistry Reference	4-Chloro-1-butanol(928-51-8)
EPA Substance Registry System	1-Butanol, 4-chloro- (928-51-8)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS02,GHS05,GHS07,GHS08

Signal word

Warning

Hazard statements

H226-H290-H302-H315-H319-H335-H351

Precautionary statements

P202-P210-P301+P312-P303+P361+P353-P305+P351+P338-P308+P313

Hazard Codes

Xn,C,F

Risk Statements

10-22-36/37/38-20/21/22-34-40

Safety Statements

23-24/25-36/37/39-26-16-36/37

RIDADR

UN 2920 8/PG 2

WGK Germany

RTECS

EL1325000

Hazard Note

Harmful

TSCA

Yes

HazardClass

3.2

PackingGroup

III

HS Code

29055910

NFPA 704

	2
3		0

4-Chloro-1-butanol price More Price(18)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	278823	4-Chloro-1-butanol technical grade, ~85%	928-51-8	50ml	$120	2024-03-01	Buy
Sigma-Aldrich	278823	4-Chloro-1-butanol technical grade, ~85%	928-51-8	250ml	$309.6	2024-03-01	Buy
TCI Chemical	C0144	4-Chloro-1-butanol (contains varying amounts of Tetrahydrofuran) >85.0%(GC)	928-51-8	25g	$58	2024-03-01	Buy
TCI Chemical	C0144	4-Chloro-1-butanol (contains varying amounts of Tetrahydrofuran) >85.0%(GC)	928-51-8	500g	$435	2024-03-01	Buy
Alfa Aesar	L04042	4-Chloro-1-butanol, tech. 85%	928-51-8	50g	$72.8	2024-03-01	Buy

Product number	Packaging	Price	Buy
278823	50ml	$120	Buy
278823	250ml	$309.6	Buy
C0144	25g	$58	Buy
C0144	500g	$435	Buy
L04042	50g	$72.8	Buy

4-Chloro-1-butanol Chemical Properties,Uses,Production

Chemical Properties

CLEAR COLOURLESS LIQUID

Uses

4-Chloro-1-butanol was employed as an internal standard in the analysis of genotoxic impurities in active pharmaceutical ingredients by GC-MS technique.

Uses

Tetramethylene chlorohydrin is used inorganic synthesis.

Uses

4-Chloro-1-butanol is employed as an internal standard in the analysis of genotoxic impurities in active pharmaceutical ingredients by GC-MS technique.

Definition

ChEBI: A primary alcohol that is butan-1-ol substituted by a chloro group at position 4.

General Description

4-Chloro-1-butanol, an alkylating agent, is one of the genotoxic impurity in active pharmaceutical ingredients. Reaction of 4-chloro-1-butanol and Reichardt′s dye has been monitored spectrophotometrically for the determination of genotoxic impurities in pharmaceuticals.

Health Hazard

The toxicity of this compound is low. How ever, the acute toxic symptoms are those ofethylene and propylene chlorohydrins. Oralintake of this compound caused muscle con traction, gastrointestinal pain, ulceration, andliver injury in test animals.
LD50 value, oral (mice): 990 mg/kg
Tetramethylene chlorohydrin caused tumorsin lungs in test animals. Its carcinogenicity,however, is not yet fully established.

Fire Hazard

Flammable; flash point 36°C (97°F); vapor density 3.7 (air = 1); the vapor forms an explosive mixture with air, range is not reported. Fire-extinguishing agent: “alcohol” foam; a water spray may be used to cool fire-exposed containers and to flush any spill. It decomposes to HCl and tetrahydrofuran on heating.

Safety Profile

Moderately toxic by ingestion. Questionable carcinogen with experimental neoplastigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of Cl-. See also CHLORIDES and ALCOHOLS.

Waste Disposal

Tetramethylene chlorohydrin is burned ina chemical incinerator equipped with anafterburner and scrubber.

4-Chloro-1-butanol Preparation Products And Raw materials

Raw materials

Preparation Products

1-(4-Morpholinobutyl)hydrazine 2-(3-CHLOROPROPYL)-1,3-DIOXOLANE 4-CHLORO-BUTYRALDEHYDE 4-Amino-1-butanol 1-Bromo-4-chlorobutane

1,3-dioxepan-2-one 1-(4-(Pyrrolidin-1-yl)butyl)hydrazine CHEMBRDG-BB 4024933 1-Piperazinebutanol(6CI,7CI,8CI,9CI)

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4-Chloro-1-butanol Suppliers

Global( 379)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12456	58
Hebei Yanxi Chemical Co., Ltd.	+8617531190177	peter@yan-xi.com	China	5993	58
Hebei Guanlang Biotechnology Co,.LTD	+8619930503252	daisy@crovellbio.com	China	5964	58
Ouhuang Engineering Materials (Hubei) Co., Ltd	+8617702722807	admin@hbouhuang.com	China	2259	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Shanghai Time Chemicals CO., Ltd.	+86-021-57951555 +8617317452075	jack.li@time-chemicals.com	China	1807	55
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10248	58
Xiamen AmoyChem Co., Ltd	+86-592-6051114 +8618959220845	sales@amoychem.com	China	6387	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58

Supplier	Advantage
Hebei Mojin Biotechnology Co., Ltd	58
Hebei Yanxi Chemical Co., Ltd.	58
Hebei Guanlang Biotechnology Co,.LTD	58
Ouhuang Engineering Materials (Hubei) Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Shanghai Time Chemicals CO., Ltd.	55
career henan chemical co	58
Shenzhen Nexconn Pharmatechs Ltd	58
Xiamen AmoyChem Co., Ltd	58
Hubei xin bonus chemical co. LTD	58

View Lastest Price from 4-Chloro-1-butanol manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-25	4-Chloro-1-butanol 928-51-8	US $10.00 / kg	1kg	99.6%	100000	Ouhuang Engineering Materials (Hubei) Co., Ltd
2024-04-25	4-Chloro-1-butanol 928-51-8	US $10.00 / kg	1kg	99.6%	100000	Ouhuang Engineering Materials (Hubei) Co., Ltd
2023-11-28	4-Chloro-1-butanol 928-51-8	US $0.00 / kg	1kg	0.99	20 tons	Hebei Yanxi Chemical Co., Ltd.

4-Chloro-1-butanol
928-51-8
US $10.00 / kg
99.6%
Ouhuang Engineering Materials (Hubei) Co., Ltd

4-Chloro-1-butanol
928-51-8
US $10.00 / kg
99.6%
Ouhuang Engineering Materials (Hubei) Co., Ltd

4-Chloro-1-butanol
928-51-8
US $0.00 / kg
0.99
Hebei Yanxi Chemical Co., Ltd.

4-Chloro-1-butanol Spectrum

4-Chloro-1-butanol(928-51-8)MS 4-Chloro-1-butanol(928-51-8)¹³CNMR 4-Chloro-1-butanol(928-51-8)IR1 4-Chloro-1-butanol(928-51-8)Raman

928-51-8(4-Chloro-1-butanol)Related Search:

Sodium tert-butoxide 1-Butanol tert-Butanol 2-Methyl-1-propanol Potassium tert-butoxide

3-Chloro-1,2-propanediol Ethambutol CYCLOBUTANE Epichlorohydrin TIROFIBAN HYDROCHLORIDE MONOHYDRATE

4-(4-Piperidyl)-1-butanol Tirofiban IMpurity (4,4'-Dipyridyl-1,5-Pentane) 1-Butanesulfonyl chloride 2-butyl-4-methylpyridine L-N-BUTYLSULFONYL-P-HYDROXYPHENYLALANINE

1-Methylethyl 1-butanesulfonate 4,4'-Dimethyl-2,2'-bipyridyl 1-Butanesulfonic acid methyl ester

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4-Choro-1-bytanol 4-CHLORO-1-BUTANOL, TECH., CA. 85% 4-Chloro-1-butanol, balance THF andHCl, 85% 4-CHLORO-1-BUTANOL TECH 85% 4-Chloro-1-butanol, tech. 85% 4-Chloro-1-butanol (contains varying amounts of Tetrahydrofuran) 4-CHLORO-1-BUTANOL GC ABOUT 90% 4-Chloro-1-butanol, 85%, balance THF and HCl 4-Chloro-1-butanol, balance THF and HCl,90-95% 4-Chloro-1-butanol ,85% [technical grade] 4-Chloro-1-butanol technical grade, ~85% 4-Chloro-1-butanol, 95%, tech. 4-Chloro-1-butanol (Technical Grade) 4 - chloride butyl alcohol 4-Chloro-1-hydroxybutane 4-Chlorobutane-1-ol 4-Chlorolbutanol 4-Chloro-n-butylclcohol Tetramethylenechlorohydrine 4-Chloro-1-butanol, Pract. 4-Chloro-1-butanol, technical, 85% 4-ChIoro-1-butanoI 4-CHLORO-1-BUTANOL 4-CHLOROBUTANOL-1 TETRAMETHYLENE CHLOROHYDRIN 1-Butanol, 4-chloro- 4-Chlorbutan-1-ol 4-Chloro-1-butane-ol 4-chloro-1-butano 4-Chloro-1-butanol(containsvaryingamountsofTetrahydrofuran)> oro-1-butanoL 4-chlorobutan-1-ol 4-CHLOROBUTANOL 928-51-8 213-175-5 ClCH24OH C4H9OCl CH2ClCH2CH2CH2OH C4H9ClO HOCH24Cl Organic Building Blocks Oxygen Compounds Building Blocks Alcohols C2 to C6 蠅-Functional Alkanols, Carboxylic Acids, Amines & Halides 蠅-Chloroalkanols Alcohols Building Blocks C2 to C6 Chemical Synthesis Organic Building Blocks Oxygen Compounds API Intermediate omega-Chloroalkanols omega-Functional Alkanols, Carboxylic Acids, Amines & Halides bc0001