Helioxanthin derivative 5-4-2
- CAS No.
- 203935-39-1
- Chemical Name:
- Helioxanthin derivative 5-4-2
- Synonyms
- CS-1214;Helioxanthin 5-4-2;Helioxanthin derivative 5-4-2;Helioxanthin derivative 542,Helioxanthin derivative 5 4 2;7H-1,3-Dioxolo[3,4]benz[1,2-f]isoindol-7-one, 10-(1,3-benzodioxol-5-yl)-8,9-dihydro-
- CBNumber:
- CB52715637
- Molecular Formula:
- C20H13NO5
- Molecular Weight:
- 347.32
- MDL Number:
- MFCD28167791
- MOL File:
- 203935-39-1.mol
Helioxanthin derivative 5-4-2 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ApexBio Technology | B4700 | Helioxanthinderivative5-4-2 | 203935-39-1 | 2mg | $368 | 2021-12-16 | Buy |
| ChemScene | CS-3197 | Helioxanthinderivative5-4-2 99.76% | 203935-39-1 | 5mg | $420 | 2021-12-16 | Buy |
| ApexBio Technology | B4700 | Helioxanthinderivative5-4-2 | 203935-39-1 | 5mg | $551 | 2021-12-16 | Buy |
| ChemScene | CS-3197 | Helioxanthinderivative5-4-2 99.76% | 203935-39-1 | 10mg | $600 | 2021-12-16 | Buy |
| ApexBio Technology | B4700 | Helioxanthinderivative5-4-2 | 203935-39-1 | 10mg | $788 | 2021-12-16 | Buy |
Helioxanthin derivative 5-4-2 Chemical Properties,Uses,Production
Biological Activity
helioxanthin derivative 5-4-2, an analogue of helioxanthin (ach126447), is a small-molecule inhibitor of hbv, hsv-1and hsv-2 virus with ec50 values of 0.08 μm, 0.29 μm and 0.16 μm, respectively [1].helioxanthin derivative 5-4-2 is a lactam and has been reported to inhibit the hbv dna and rna and viral protein expression [2]. helioxanthin derivative 5-4-2 has significant anti-virus activity with ec50 values of 0.08 μm, 0.29 μm and 0.16 μm for hbv(hepatitis b virus), hsv-1(herpes simplex virus type 1) and hsv-2(herpes simplex virus type 2), respectively [1]. in addition, helioxanthin derivative 5-4-2 inhibited hbv replication by post-transcriptional down-regulation of necessary transcription factors [3]. helioxanthin derivative 5-4-2 has also exhibited potent anti-hcv (hepatitis c virus) activity with 55% inhibition at 1.0 μm and 80%inhibition at 3.0 μm [1].
References
[1] yeo h1, li y, fu l, zhu jl, gullen ea, dutschman ge, lee y, chung r, huang es, austin dj, cheng yc. synthesis and antiviral activity of helioxanthin analogues. j med chem. 2005 jan 27;48(2):534-46.
[2] li y1, fu l, yeo h, zhu jl, chou ck, kou yh, yeh sf, gullen e, austin d, chengyc.inhibition of hepatitis b virus gene expression and replication by helioxanthin and its derivative. antivir chem chemother. 2005;16(3):193-201.
[3] stein ll1, loomba r. drug targets in hepatitis b virus infection. infect disord drug targets. 2009 apr;9(2):105-16.
Helioxanthin derivative 5-4-2 Preparation Products And Raw materials
Raw materials
Preparation Products
Helioxanthin derivative 5-4-2 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4863 | 58 |
| SPIRO PHARMA | eric_feng1954@126.com | China | 9254 | 55 | |
| BOC Sciences | 16314854226 | info@bocsci.com | United States | 9926 | 65 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 18892239720 | psaitong@jm-bio.com | China | 12308 | 58 |
| Musechem | +1-800-259-7612 | info@musechem.com | United States | 4662 | 60 |
| Shenzhen Regent Biochemical Technology Co., Ltd. | 0755-0755-85201366 18938635012 | sales@regentsciences.com | China | 9293 | 58 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9730 | 58 |
| Hangzhou Synstar pharmaceutical Technology CO.,Ltd | 0571-85361029 | synstar518@163.com | China | 1991 | 58 |