Nexturastat A
- CAS No.
- 1403783-31-2
- Chemical Name:
- Nexturastat A
- Synonyms
- CS-1289;Nexturastat A;Nextunastat A;Nexturastat A, >97%;Nexturastat A, >=98%;Nexturastat A (AG-CR1-3901);4-((1-BUTYL-3-PHENYLUREIDO)METHYL)-N-HYDROXYBENZAMIDE;4-[[butyl(phenylcarbamoyl)amino]methyl]-N-hydroxybenzamide;4-[[Butyl[(phenylamino)carbonyl]amino]methyl]-N-hydroxybenzamide;Benzamide, 4-[[butyl[(phenylamino)carbonyl]amino]methyl]-N-hydroxy-
- CBNumber:
- CB52715657
- Molecular Formula:
- C19H23N3O3
- Molecular Weight:
- 341.4
- MDL Number:
- MFCD28099804
- MOL File:
- 1403783-31-2.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P280-P305+P351+P338 | |||||||||
| NFPA 704 |
|
Nexturastat A price More Price(25)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 16874 | Nexturastat A ≥95% | 1403783-31-2 | 500μg | $62 | 2024-03-01 | Buy |
| Cayman Chemical | 16874 | Nexturastat A ≥95% | 1403783-31-2 | 1mg | $109 | 2024-03-01 | Buy |
| Cayman Chemical | 16874 | Nexturastat A ≥95% | 1403783-31-2 | 5mg | $477 | 2024-03-01 | Buy |
| Cayman Chemical | 16874 | Nexturastat A ≥95% | 1403783-31-2 | 10mg | $834 | 2024-03-01 | Buy |
| TRC | N391500 | NexturastatA | 1403783-31-2 | 25mg | $1760 | 2021-12-16 | Buy |
Nexturastat A Chemical Properties,Uses,Production
Uses
Nexturastat A is a potent and selective histone deacetylase 6 (HDAC6) inhibitor that shows potential antiproliferative effects against melanoma cells.
Biological Activity
nexturastat a is a selective inhibitor of histone deacetylase 6 (hdac6) with ic50 value of 5.2 nm [1].nexturastat a is a hdac inhibitor. it was developed by structural modification of aryl urea hdacis. the inhibitory activity of nexturastat a is most potent against hdac6 with ic50 value of 5.2 nm. besides that, nexturastat a also shows inhibition of other hdacs with ic50 values of 3.02, 6.92, 6.68, 9.39, 11.7, 4.46, 0.954, 6.72, 7.57 and 5.14 μm for hdac1, 2, 3, 4, 5, 7, 8, 9, 10 and 11, respectively. nexturastat a has been shown to suppress cell proliferation and promote apoptosis in b16 murine melanoma cells [1, 2].
target
HDAC6
References
[1] kalin j h, bergman j a. development and therapeutic implications of selective histone deacetylase 6 inhibitors. journal of medicinal chemistry, 2013, 56(16): 6297-6313.
[2] zhang l, han y, jiang q, et al. trend of histone deacetylase inhibitors in cancer therapy: isoform selectivity or multitargeted strategy. medicinal research reviews, 2014.
Nexturastat A Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24738 | 58 |
| Coresyn Pharmatech Co., Ltd. | +86-571-86626709 +86-18157142896 | cbc@coresyn.com | China | 9991 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
View Lastest Price from Nexturastat A manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-09-05 | 4-((1-BUTYL-3-PHENYLUREIDO)METHYL)-N-HYDROXYBENZAMIDE
1403783-31-2
|
US $1.00 / ASSAYS | 1ASSAYS | 98% | 10kg | Career Henan Chemical Co |
-
- 4-((1-BUTYL-3-PHENYLUREIDO)METHYL)-N-HYDROXYBENZAMIDE
1403783-31-2
- US $1.00 / ASSAYS
- 98%
- Career Henan Chemical Co