ChemicalBook >> CAS DataBase List >>CP671305
CP671305
- CAS No.
- 445295-04-5
- Chemical Name:
- CP671305
- Synonyms
- CS-2886;CP671305;UNII-9LH034R9R9;CP-671305; CP 671305; CP671305; UNII-9LH034R9R9;445295-04-5;CP 671305,Inhibitor,Phosphodiesterase (PDE),CP671305,CP-671305,inhibit;(R)-2-(4-((2-(benzo[d][1,3]dioxol-5-yloxy)nicotinamido)methyl)-3-fluorophenoxy)propanoic acid;Propanoic acid, 2-[4-[[[[2-(1,3-benzodioxol-5-yloxy)-3-pyridinyl]carbonyl]amino]methyl]-3-fluorophenoxy]-, (2R)-
- CBNumber:
- CB53175535
- Molecular Formula:
- C23H19FN2O7
- Molecular Weight:
- 454.4
- MDL Number:
- MFCD31382154
- MOL File:
- 445295-04-5.mol
Last updated:2023-05-21 10:59:17
| storage temp. | Store at -20°C |
|---|---|
| solubility | DMF: 50 mg/ml; DMSO: 25 mg/ml; Ethanol: 3 mg/ml; PBS (pH 7.2): 2 mg/ml |
| form | A crystalline solid |
| FDA UNII | 9LH034R9R9 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
CP671305 price More Price(17)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 26743 | CP 671,305 | 445295-04-5 | 1mg | $44 | 2024-03-01 | Buy |
| Cayman Chemical | 26743 | CP 671,305 | 445295-04-5 | 10mg | $341 | 2024-03-01 | Buy |
| Cayman Chemical | 26743 | CP 671,305 | 445295-04-5 | 5mg | $193 | 2024-03-01 | Buy |
| ChemScene | CS-6774 | CP671305 99.95% | 445295-04-5 | 25mg | $250 | 2021-12-16 | Buy |
| Biosynth Carbosynth | BC161230 | CP 671305 | 445295-04-5 | 2mg | $250 | 2021-12-16 | Buy |
CP671305 Chemical Properties,Uses,Production
Description
CP 671,305 is a potent inhibitor of phosphodiesterase 4D (PDE4D; IC50 = 3 nM). It is selective for PDE4D over PDE4A, -B, and -C (IC50s = 310, 287, and 3,858 nM, respectively), as well as over PDE1-3 and 5 (IC50s = >5,000 nM for all). CP 671,305 inhibits release of leukotriene E4 (LTE4; ) from eosinophils (IC50 = 52 nM) and LTB4 from neutrophils (IC50 = 106 nM). In vivo, CP 671,305 inhibits antigen-induced pulmonary eosinophil influx in cynomolgus monkeys in a dose-dependent manner.
CP671305 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 37)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
| Chemia Biotechnology（Shanghai） Co., Ltd | +8613816753574 | info@chemia-pharm.com | CHINA | 311 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4153 | 55 | |
| Shanghaizehan biopharma technology co., Ltd. | 021-61350663 13052117465 | sales@zehanbiopharma.com | China | 991 | 55 |
| ShangHai Biochempartner Co.,Ltd | 17754423994 17754423994 | 2853530910@QQ.com | China | 8012 | 62 |
| Shanghai Rechem science Co., Ltd. | 21-31433387 15618786686 | sales@rechemscience.com | China | 2985 | 58 |
| Shanghai Chaolan Chemical Technology Center | QQ:65489617 15618227136 | info@SuperLan-chem.com | China | 9747 | 58 |
445295-04-5(CP671305)Related Search:
5-(2-HYDROXY-BENZYLIDENE)-THIAZOLIDINE-2,4-DIONE
4-Chloro-N,N-diethylbenzaMide, 97%
4-Chloro-N,N-di-n-propylbenzaMide, 97%
TIMTEC-BB SBB006342
NSC781406
1of4
CP671305
CP-671305; CP 671305; CP671305; UNII-9LH034R9R9;445295-04-5
UNII-9LH034R9R9
CS-2886
Propanoic acid, 2-[4-[[[[2-(1,3-benzodioxol-5-yloxy)-3-pyridinyl]carbonyl]amino]methyl]-3-fluorophenoxy]-, (2R)-
(R)-2-(4-((2-(benzo[d][1,3]dioxol-5-yloxy)nicotinamido)methyl)-3-fluorophenoxy)propanoic acid
CP 671305,Inhibitor,Phosphodiesterase (PDE),CP671305,CP-671305,inhibit
445295-04-5
API