ChemicalBook >> CAS DataBase List >>N-(Trimethylsilyl)imidazole

N-(Trimethylsilyl)imidazole

N-(Trimethylsilyl)imidazole structure

CAS No.: 18156-74-6

Chemical Name:: N-(Trimethylsilyl)imidazole

Synonyms: TMSI;TMSIM;TRIMETHYLSILYLIMIDAZOLE;TSIM;TMS-IMIDAZOLE;1-(TRIMETHYLSILYL)IMIDAZOLE;SIM;1-(TRIMETHYLSILYL)-1H-IMIDAZOLE;1-(TRIMETHYLSILYL)IMIDAZOLE, 97%1-(TRIMETHYLSILYL)IMIDAZOLE, 97%1-(TRIMETHYLSILYL)IMIDAZOLE, 97%;Trimethylimidazosilane

CBNumber:: CB5483743

Molecular Formula:: C6H12N2Si

Molecular Weight:: 140.26

MDL Number:: MFCD00005280

MOL File:: 18156-74-6.mol

MSDS File:: SDS

Last updated:2024-04-28 19:50:54

Request For Quotation

N-(Trimethylsilyl)imidazole Properties

Melting point	-42 °C
Boiling point	93-94 °C14 mm Hg(lit.)
Density	0.957 g/mL at 20 °C
refractive index	n20/D 1.475(lit.)
Flash point	42 °F
storage temp.	Store below +30°C.
solubility	Chloroform
form	Liquid
pka	7.96±0.10(Predicted)
Specific Gravity	0.956
color	Clear colorless to yellow
Water Solubility	decomposes
Sensitive	Moisture Sensitive
Hydrolytic Sensitivity	7: reacts slowly with moisture/water
BRN	606148
Stability	Air and Moisture Sensitive
InChIKey	YKFRUJSEPGHZFJ-UHFFFAOYSA-N
CAS DataBase Reference	18156-74-6(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	PX8K4R8KWX
NIST Chemistry Reference	1h-Imidazole, 1-(trimethylsilyl)-(18156-74-6)
EPA Substance Registry System	1H-Imidazole, 1-(trimethylsilyl)- (18156-74-6)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS02,GHS07

Signal word

Danger

Hazard statements

H225-H315-H319-H335

Precautionary statements

P210-P233-P240-P241-P303+P361+P353-P305+P351+P338

Hazard Codes

F,Xi,C

Risk Statements

11-36/37/38-14-40-34-37-35-20/21/22

Safety Statements

16-26-33-37/39-45-36/37/39

RIDADR

UN 1993 3/PG 2

WGK Germany

RTECS

NI8700000

10-21

Autoignition Temperature

540 °C DIN 51794

TSCA

HazardClass

PackingGroup

HS Code

29332990

NFPA 704

	3
2		1

N-(Trimethylsilyl)imidazole price More Price(49)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	8.18204	N-(Trimethylsilyl)imidazole for synthesis	18156-74-6	25mL	$88.1	2024-03-01	Buy
Sigma-Aldrich	8.18204	N-(Trimethylsilyl)imidazole for synthesis	18156-74-6	100mL	$267	2024-03-01	Buy
Sigma-Aldrich	153583	1-(Trimethylsilyl)imidazole 96%	18156-74-6	5ml	$48.3	2024-03-01	Buy
Sigma-Aldrich	153583	1-(Trimethylsilyl)imidazole 96%	18156-74-6	25ml	$128	2024-03-01	Buy
Sigma-Aldrich	1.09771	N-(Trimethylsilyl)imidazole for gas chromatography	18156-74-6	5ml	$214	2024-03-01	Buy

Product number	Packaging	Price	Buy
8.18204	25mL	$88.1	Buy
8.18204	100mL	$267	Buy
153583	5ml	$48.3	Buy
153583	25ml	$128	Buy
1.09771	5ml	$214	Buy

N-(Trimethylsilyl)imidazole Chemical Properties,Uses,Production

Chemical Properties

Colorless transparent liquid

Physical properties

bp 93–94 °C/14 mmHg; fp 5 °C; d 0.956 g cm?3.

Uses

N-(Trimethylsilyl)imidazole is a silylating agent for alcohols and 1,3-dicarbonyl compounds; reaction with esters to give imidazolides; preparation of O-trimethylsilyl monothioacetals; aromatization of the A-ring of steroids. It participates in the reactions of Hydroxyl Silylation Reactions, Silyl Aminal Formation Reactions, Nitrogen Silylation Reactions, Acyl Imidazole Formation, Michael Addition Reactions, Substitution Reactions, Phosphoroimidazolidate Formation, and other uses.

Uses

A general silylating agent, particularly for alcohols. An intermediate for the synthesis of imidazole derivatives.

Uses

N-(trimethylsilyl) imidazole (TMSim) is quite reactive with hydroxyl groups in a variety of analytes including a variety of lipids.As with other derivatization reactions,microwave heating can greatly improve process efficiency.

Uses

Silylating reagent for the protection of hydroxyl groups in the presence of amine functionalities.1

Definition

ChEBI: A member of the class of imidazoles in which the hydrogen at position 1 is replaced by a trimethylsilyl group. N-trimethylsilylimidazole is a derivatisation agent used in gas chromatography/mass spectrometry applications.

General Description

1-(Trimethylsilyl)imidazole (TMSIM) has high silyl donor ability. It does not react with amino groups and also does not help in formation of enol-ether on unprotected ketone groups. It is useful as a silylating agent for ecdysones, norepinephrine, dopamine, steroids, sugars, sugar phosphates and ketose isomers.

N-(Trimethylsilyl)imidazole Preparation Products And Raw materials

Raw materials

Preparation Products

Medetomidine 4-TRIMETHYLSILOXY-3-PENTEN-2-ONE Chlorotrimethylsilane 1,1'-Sulfonyldiimidazole N,N'-BIS(IMIDAZOLE)DIMETHYLSILANE,TECH-95

2-O,3-O,4-O,5-O-Tetrakis(trimethylsilyl)-D-ribose 1,1'-Thiocarbonyldiimidazole

1of2

N-(Trimethylsilyl)imidazole Suppliers

Global( 499)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12456	58
Hubei Changfu Chemical Co., Ltd.	+86-027-84396550 +8617721064038	sales@cfsilanes.com	China	401	58
Hebei Saisier Technology Co., LTD	+86-18400010335 +86-13102810335	admin@hbsaisier.cn	China	772	58
Ouhuang Engineering Materials (Hubei) Co., Ltd	+8617702722807	admin@hbouhuang.com	China	2642	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15933	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
Nanjing ChemLin Chemical Industry Co., Ltd.	025-83697070	product@chemlin.com.cn	CHINA	3012	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
Zjartschem	+86-571-8723 8903 jocelynpan@zjarts.com	jocelynpan@zjarts.com	CHINA	993	58

Supplier	Advantage
Hebei Mojin Biotechnology Co., Ltd	58
Hubei Changfu Chemical Co., Ltd.	58
Hebei Saisier Technology Co., LTD	58
Ouhuang Engineering Materials (Hubei) Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Nanjing ChemLin Chemical Industry Co., Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
Zjartschem	58

View Lastest Price from N-(Trimethylsilyl)imidazole manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-28	N-(Trimethylsilyl)imidazole 18156-74-6	US $6.00 / kg	1kg	More than 99%	2000KG/Month	Hebei Longbang Technology Co., Ltd
2024-04-28	N-(Trimethylsilyl)imidazole 18156-74-6	US $0.00 / kg	1kg	96%	20t	Hubei Changfu Chemical Co., Ltd.
2024-04-24	N-(Trimethylsilyl)imidazole 18156-74-6	US $15.00 / kg	1kg	99.912%	10ton	Ouhuang Engineering Materials (Hubei) Co., Ltd

N-(Trimethylsilyl)imidazole
18156-74-6
US $6.00 / kg
More than 99%
Hebei Longbang Technology Co., Ltd

N-(Trimethylsilyl)imidazole
18156-74-6
US $0.00 / kg
96%
Hubei Changfu Chemical Co., Ltd.

N-(Trimethylsilyl)imidazole
18156-74-6
US $15.00 / kg
99.912%
Ouhuang Engineering Materials (Hubei) Co., Ltd

N-(Trimethylsilyl)imidazole Spectrum

N-(Trimethylsilyl)imidazole(18156-74-6)MS N-(Trimethylsilyl)imidazole(18156-74-6)¹HNMR N-(Trimethylsilyl)imidazole(18156-74-6)¹³CNMR

18156-74-6(N-(Trimethylsilyl)imidazole)Related Search:

(Trifluoromethyl)trimethylsilane Trimethylsilyl cyanide TRIMETHYLSILANE Potassium trimethylsilanolate Hexamethyldisilazane

1-Methylimidazole Imidazole Trimethylsilylacetylene Azidotrimethylsilane hydroxytrimethylsilane

N-(Trimethylsilyl)acetamide Iodotrimethylsilane Pyridine sulfur trioxide Chlorotrimethylsilane Bromotrimethylsilane

N-6,9-BIS(TRIMETHYLSILYL)ADENINE Silicon N-(TRIMETHYL-D9-SILYL)IMIDAZOLE

1of4

N-Trimethylsilylimidazole, 95+% 1-Trimethysiylimidazole 1H-Imidazole, 1-(trimethylsilyl)- n-trimethylsilylimidazole kit sim kit tms-imidazole(sim) kit N-TRIMETHYSIYLIMIDAZOLE 1-(Trimethylsily)imidazole N-TRIMETHYLSILIMIDAZOLE TIMTEC-BB SBB009056 TRI-SIL Z TMS iodine 1-(TriMethylsilyl)iMidazole >=98.0% TriMethylsilyl iMidazole (TSIM) N-Trimethylsilylimidazole 1-(Trimethylsilyl)imidazole(TMSI、TSIM) N-Trimethylsilylimidazole TMSI TMS-Imidazole 1-(trimethylsilyl)-1H-Imidazole n-(trimethylsilyl)-imidazo TSIM N-(Trimethylsilyl)imidazole for synthesis TMS-Imidazole (=N-Trimethylsilylimidazole) [for Gas Chromatography] N-TriMethysilyliMidazole TMSI (N-triMethylsilyliMidazole) 1-(TriMethylsilyl)iMidazole (TSIM) Trimethylsilylimidzole 1-(trimethylsilyl)-1h-imidazol 1-(trimethylsilyl)-imidazol 1-Imidazolyltrimethylsilane CT3600 Imidazole, 1-(trimethylsilyl)- Imidazole, N-(trimethylsilyl)- N-(Trimethylsilyl)imidazol n-(trimethylsilyl)-imidazol N-Trimethylsilylimidazole Kit SIM 1 ml * 8 / Reaction vial, capacity 2 ml * 8 N-(Trimethylsilyl)imidazole,97% N-Trimethylsilylimidazole [Trimethylsilylating Reagent] N-Trimethylsilylimidazole Kit SIM 1 ml * 8 / Reaction vial, capacity 2 ml * 8 [Trimethylsilylating Reagent] N-(Trimethylsilyl)im TMS-IMidazole (=N-TriMethylsilyliMidazole) N-(TriMethylsilyl)-1H-iMidazole NSC 139860 SIM Kit TMS-Imidazole Kit TMSI Kit TMS-Imidazole SIM TMSI SIM N-Trimethylsilylimidazole TMSI 1-Trimethylsilyllimidazole N-Trimethylsilylimidazole ,98% 1-(Trimethylsilyl)imidazole,N-Trimethylsilylimidazole, TMSI N-(TRIMETHYLSILYL)IMIDAZOLE FOR SYNTHESI N-(TRIMETHYLSILYL)IMIDAZOLE FOR GAS CHRO N-(TriMethylsilyl)iMidazole, 97% 25GR N-trimethylsiylimidazole N-Trimethylsilylimidazole(TMSI) 1-(TRIMETHYLSILYL)IMIDAZOLE, DERIVATIZAT ION GRADE N-TRIMETHYLSILYLIMIDAZOLE [FOR GAS CHROMATOGRAPHY] N-TrimethylsilylimidazoleA.R Ht--407 (Trimethylsilyl)Imidazole (Tsim) N-Trimethylsilylimidazole [Trimethylsilylating Reagent]> N-Trimethylsilylimidazole Kit SIM 1 mL * 8 / Reaction vial, capacity 2 mL * 8[Trimethylsilylating Reagent]> N-Trimethylsilylimidazole, 98%, reagent grade TMS-Imidazole(=N-Trimethylsilylimidazole)[forGasChromatography]>