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Urea

CAS No.57-13-6
Chemical Name:Urea
Synonyms:URE;UREA;UREUM;B-I-K;Hyanit;UreaAr;UreaGr;UreaBp;UreaIp;Panafil
CBNumber:CB5853861
Molecular Formula:CH4N2O
Formula Weight:60.06
MOL File:57-13-6.mol
Urea Property
mp : 132-135 °C(lit.)
density : 1.335 g/mL at 25 °C(lit.)
refractive index : n20/D 1.40
storage temp. : 2-8°C
solubility : H2O: 8 M at 20 °C
form : powder
color : white
Water Solubility : 1080 g/L (20 ºC)
Merck : 14,9867
BRN : 635724
Stability:: Substances to be avoided include strong oxidizing agents. Protect from moisture.
CAS DataBase Reference: 57-13-6(CAS DataBase Reference)
NIST Chemistry Reference: Urea(57-13-6)
EPA Substance Registry System: Urea(57-13-6)
Safety
Hazard Codes : Xn,Xi
Risk Statements : 36/37/38-40
Safety Statements : 26-36-24/25
WGK Germany : 1
RTECS : YR6250000
HS Code : 31021010
Hazardous Substances Data: 57-13-6(Hazardous Substances Data)

Urea Chemical Properties,Usage,Production

Chemical Properties
White crystalline powder
Usage
Used for the denaturation of proteins and as a mild solubilization agent for insoluble or denatured proteins. Useful for renaturing proteins from samples already denatured with 6 M guanidine chloride such as inclusion bodies. May be used with guanidine hydrochloride and dithiothreitrol (DTT) in the refolding of denatured proteins into their native or active form.
Usage
anticholelithogenic; LD50(rat) 890 mg/kg ip
Usage
Urea is a physiological regulator of nitrogen excretion in mammals; synthesized in the liver as an end-product of protein catabolism and excreted in urine. Also occurs normally in skin. Emollient; diu retic.
General Description
Solid odorless white crystals or pellets. Density 1.335 g /cc. Noncombustible.
Air & Water Reactions
Water soluble.
Reactivity Profile
Urea is a weak base. Reacts with hypochlorites to form nitrogen trichloride which explodes spontaneously in air [J. Am. Chem. Soc. 63:3530-32]. Same is true for phosphorus pentachloride. Urea reacts with azo and diazo compounds to generate toxic gases. Reacts with strong reducing agents to form flammable gases (hydrogen). The heating of improper stoichiometric amounts of Urea and sodium nitrite lead to an explosion. Heated mixtures of oxalic acid and Urea yielded rapid evolution of gases, carbon dioxide, carbon monoxide and ammonia (if hot, can be explosive). Titanium tetrachloride and Urea slowly formed a complex during 6 weeks at 80°C., decomposed violently at 90°C., [Chem. Abs., 1966, 64, 9219b]. Urea ignites spontaneously on stirring with nitrosyl perchlorate, (due to the formation of the diazonium perchlorate). Oxalic acid and Urea react at high temperatures to form toxic and flammable ammonia and carbon monoxide gasses, and inert CO2 gas [Von Bentzinger, R. et al., Praxis Naturwiss. Chem., 1987, 36(8), 41-42].
Health Hazard
May irritate eyes.
Fire Hazard
Behavior in Fire: Melts and decomposes, generating ammonia.
Urea Preparation Products And Raw materials
Raw materials
Liquefied petroleum ges HEAVY CUT RESIDUE OIL Glycine CARBON DIOXIDE 2,2'-Iminodiethanol METALLURGICAL COKE PETROLEUM ETHER Vanadium pentoxide Acetic acid glacial AMMONIUM CARBAMATE Ammonia
Preparation Products
Reactive Black KN-BN ureaformaldelyde resin UF 5-CARBETHOXYURACIL 2,4-DICHLOROTHIENO[3,2-D]PYRIMIDINE DIHYDROTHYMINE Furacilin Tanning agent for white leather synthetic carbamider ring tanning agent No.1 1-(2-Aminoethyl)imidazolidin-2-one DIRECT FAST BLACK G Carbachol 5,6-DIHYDROURACIL Pigment Yellow 65 6-Aminouracil flame retardane ZR-01 Thieno[3,2-d]pyrimidine, 2,4-dichloro- 2,6-Dichloro-4,8-dipiperidinopyrimidino[5,4-d]pyrimidine biodegrddable finishing agent for fabric BIUREA 1-(1,3-DIHYDRO-1-OXOISOBENZOFURAN-3-YL)UREA N,N''-(isobutylidene)diurea 1-Methyl-1-nitrosourea 4,5-dihydroxy-1,3-bis(hydroxymethyl)imidazolidin-2-one 3-Hydroxy-1-phenyl-1,2,4-triazole DICHLOROISOCYANURIC ACID Cymoxanil 2,4,6,8-Tetrahydroxy-Pyrimido-(5,4D)Pyrimidine Urea hydrogen peroxide 5-(sec-pentyl)barbituric acid Amino moulding plastic Tableware cleaner synthetic tanning agent PNC rubber latex 104T/C Biuret ETHYL 2-HYDROXYPYRIMIDINE-5-CARBOXYLATE 1-PHENYLSEMICARBAZIDE ALLYLUREA Water flush fertilizer 2-HYDROXY-4-PHENYLPYRIMIDINE-5-CARBOXYLIC ACID 2,4-DIHYDROXYTHIENO[3,2-D]PYRIMIDINE
Urea Suppliers      Global( 171)Suppliers     
SupplierTelFaxEmailCountryProdListAdvantage
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833+86-10-82849933jkinfo@jkchemical.com;market3@jkchemical.comCHINA 96869 76
Meryer (Shanghai) Chemical Technology Co., Ltd. +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-62670440(Beijing)+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-62670790(Beijing)sh@meryer.com; sz@meryer.comCHINA 40414 62
Alfa Aesar 400-610-6006; 021-67582000021-67582001/03/05saleschina@alfa-asia.comCHINA 30343 84
TCI (Shanghai) Development Co., Ltd. 800-988-0390021-67121385sales@tcishanghai.com.cnCHINA 22161 81
ShangHai DEMO Chemical Co.,Ltd 0086-21-50182335 400-021-73370086-21-50182339sales@demochem.com; export1@demochem.comCHINA 4182 57
Beijing dtftchem Technology Co., Ltd. 手机13651141086; 86(10)60275028、6027582086 (10) 60270825dtftchem@sina.comCHINA 4701 62
BeiJing Hwrk Chemicals Limted 4006990298 010-57411839 020-31335234 021-51691807010-87653215 0757-86311057 021-55236763sales@hwrkchemical.comCHINA 13342 55
Energy Chemical 021-58432009 / 400-005-6266021-58436166-800info@energy-chemical.comCHINA 44202 61
Beijing Ouhe Technology Co., Ltd +86-10-4006331231;+86-10-51280831;+86-10-82967028+86-10-82967029sales@ouhechem.comCHINA 10586 60
JinYan Chemicals(ShangHai) Co.,Ltd. 13817811078,021-5042603086-021-50426522,50426273sales@jingyan-chemical.comCHINA 10118 60
 
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