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ChemicalBook >> CAS DataBase List >>2,4,6,8-Tetrahydroxy-Pyrimido-(5,4D)Pyrimidine

2,4,6,8-Tetrahydroxy-Pyrimido-(5,4D)Pyrimidine

2,4,6,8-Tetrahydroxy-Pyrimido-(5,4D)Pyrimidine Structure
2,4,6,8-Tetrahydroxy-Pyrimido-(5,4D)Pyrimidine structure
CAS No.
6713-54-8
Chemical Name:
2,4,6,8-Tetrahydroxy-Pyrimido-(5,4D)Pyrimidine
Synonyms
Nsc20089;Homouric;tetratomic;homouric acid;Dipyridamole Impurity 8;2,6,8,10-Tetrahydroxy-homopurine;Pyrimido[5,4-d]Pyrimidine Impurity 1;Pyrimido[5,4-d]pyrimidine-2,4,6,8-tetrol;pyrimido[5,4-d]pyrimidine-2,4,6,8-tetraol;pyriMido[5,4-d][1,3]diazine-2,4,6,8-tetrol
CBNumber:
CB6875585
Molecular Formula:
C6H4N4O4
Molecular Weight:
196.12
MDL Number:
MFCD00129147
MOL File:
6713-54-8.mol
Last updated:2022-12-21 16:56:50
Request For Quotation

2,4,6,8-Tetrahydroxy-Pyrimido-(5,4D)Pyrimidine Properties

Density 1.89±0.1 g/cm3(Predicted)
pka 5.90±0.20(Predicted)
FDA UNII KMA8ZVL3X3

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338

2,4,6,8-Tetrahydroxy-Pyrimido-(5,4D)Pyrimidine price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC T796778 2,4,6,8-Tetrahydroxypyrimido[5,4-d]pyrimidine 6713-54-8 10mg $45 2021-12-16 Buy
Matrix Scientific 073607 2,4,6,8-Tetrahydroxypyrimido[5,4-d]pyrimidine 95+% 6713-54-8 5g $55 2021-12-16 Buy
AK Scientific W7772 2,4,6,8-Tetrahydroxypyrimido-[5,4-d]pyrimidine 6713-54-8 100mg $39 2021-12-16 Buy
AK Scientific W7772 2,4,6,8-Tetrahydroxypyrimido-[5,4-d]pyrimidine 6713-54-8 1g $156 2021-12-16 Buy
Matrix Scientific 073607 2,4,6,8-Tetrahydroxypyrimido[5,4-d]pyrimidine 95+% 6713-54-8 25g $180 2021-12-16 Buy
Product number Packaging Price Buy
T796778 10mg $45 Buy
073607 5g $55 Buy
W7772 100mg $39 Buy
W7772 1g $156 Buy
073607 25g $180 Buy

2,4,6,8-Tetrahydroxy-Pyrimido-(5,4D)Pyrimidine Chemical Properties,Uses,Production

Uses

2,4,6,8-Tetrahydroxy-Pyrimido(5,4-d)Pyrimidine is a pharmaceutical intermediate used in the preparation of Dipyridamole, an antiplatelet drug that is used primarily in the treatment of ischaemic heart disease and stroke. 2,4,6,8-Tetrahydroxy-Pyrimido(5,4-d)Pyrimidine is also used as a herbicide to control broadleaf weeds in wheat crops.

Synthesis

2,4,6,8-Tetrahydroxy-Pyrimido-(5,4d)Pyrimidine is prepared by the reaction of 5-amino-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid and urea. The specific synthesis steps are as follows:
5-amino-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid was charged into a two nicked flask, Urea (7.7 g, 128.0 mmol) was added dropwise with 125 ml of NaOH solution (500 g of sodium hydroxide + 1500 g of purified water) After dripping rapidly warming to 100 ° C,Insulation for one hour; continue to stir 3h,(25 ° C), filtered to obtain a solid, add purified water 250ml, heated to 60 ° C, heat lh, and then add dilute hydrochloric acid to ΡΗ = 4, cooled to room temperature filtration, washed and dried to obtain pyrimidine [5 , 4-d] pyrimidine-2,4,6,8-tetraol (tetrahydroxy), and recrystallized (ethanol solvent) to give 10.9 g in 86.9% yield.
2,4,6,8-Tetrahydroxy-Pyrimido-(5,4D)Pyrimidine synthesis

2,4,6,8-Tetrahydroxy-Pyrimido-(5,4D)Pyrimidine Preparation Products And Raw materials

Raw materials

5-AMINOOROTIC ACID Urea

Preparation Products

2,4,6,8-TETRACHLOROPYRIMIDO[5,4-D]PYRIMIDINE 2,6-Dichloro-4,8-dipiperidinopyrimidino[5,4-d]pyrimidine

2,4,6,8-Tetrahydroxy-Pyrimido-(5,4D)Pyrimidine Suppliers

Global( 116)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
Zhejiang ZETian Fine Chemicals Co. LTD 		18957127338 stella@zetchem.com China 2141 58
Standardpharm Co. Ltd. 		86-714-3992388 overseasales1@yongstandards.com United States 14336 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63711 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49390 58
career henan chemical co 		+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
SIMAGCHEM CORP 		+86-13806087780 sale@simagchem.com China 17367 58
Hefei TNJ Chemical Industry Co.,Ltd. 		0551-65418671 sales@tnjchem.com China 34572 58
Shanxi Xuanran Import and Export Trade Co., Ltd. 		+8617735180244 mike_yan@xuanranglobal.com CHINA 4022 58
Supplier Advantage
Capot Chemical Co.,Ltd. 		60
Henan Tianfu Chemical Co.,Ltd. 		55
Zhejiang ZETian Fine Chemicals Co. LTD 		58
Standardpharm Co. Ltd. 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
career henan chemical co 		58
SIMAGCHEM CORP 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
Shanxi Xuanran Import and Export Trade Co., Ltd. 		58

View Lastest Price from 2,4,6,8-Tetrahydroxy-Pyrimido-(5,4D)Pyrimidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,4,6,8-Tetrahydroxy-Pyrimido-(5,4D)Pyrimidine pictures 2020-01-03 2,4,6,8-Tetrahydroxy-Pyrimido-(5,4D)Pyrimidine
6713-54-8
 US $6.60 / KG 1KG 97%-99% 1kg -1000kg Career Henan Chemical Co

6713-54-8(2,4,6,8-Tetrahydroxy-Pyrimido-(5,4D)Pyrimidine)Related Search:

Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate Dipyridamole Mono-O-b-D-glucuronide Dipyridamole 2,6-Dichloro-4,8-dipiperidinopyrimidino[5,4-d]pyrimidine 2,4,6,8-TETRACHLOROPYRIMIDO[5,4-D]PYRIMIDINE
2-[[2-[bis(2-hydroxyethyl)amino]-4,8-bis(2,2,3,3,4,4,5,5,6,6-decadeuteriopiperidin-1-yl)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol 2,2',2'',2'''-[[4-[(2-Hydroxyethyl)aMino]-8-(1-piperidinyl)pyriMido[5,4-d]pyriMidine-2,6-diyl]dinitrilo]tetrakisethanol (DipyridaMole IMpurity) Dipyridamole Tripiperidine Dipyridamole Tri(diethanolamine) 6-Des(diethanolamino)-6-chloro Dipyridamole
4,8-dichloro-2,6-dipiperidinopyrimido[5,4-d]pyrimidine Desethanol Dipyridamole Pyrimido[5,4-d]pyrimidin-4-ol (8CI) 2,4,6,8-Tetrahydroxy-Pyrimido-(5,4D)Pyrimidine

1of3

1,5-dihydropyrimido[5,4-d]pyrimidine-2,4,6,8(3H,7H)tetrone 2,6,8,10-Tetrahydroxy-homopurine 2,4,6,8-Tetrahydroxy-Pyrimido-(5,4D)Pyrimidine Homouric homouric acid 1,2,3,4,5,6,7,8-Octahydropyrimido[5,4-d]pyrimidine-2,4,6,8-tetrone Pyrimido[5,4-d]pyrimidine-2,4,6,8(1H,3H,5H,7H)-tetrone Pyrimido[5,4-d]pyrimidine-2,4,6,8-tetrol Nsc20089 pyriMido[5,4-d][1,3]diazine-2,4,6,8-tetrol pyriMido[5,4-d]pyriMidine-2,4,6,8(1H,3H,5H,7H)-tetraone pyrimido[5,4-d]pyrimidine-2,4,6,8-tetraol 1H,2H,3H,4H,5H,6H,7H,8H-[1,3]DIAZINO[5,4-D]PYRIMIDINE-2,4,6,8-TETRONE 1,5-dihydropyrimido[5,4-d]pyrimidine-2,4,6,8-tetrone ,4,6,8-Tetrahydroxy-Pyrimido-(5,4D)Pyrimidine Dipyridamole Impurity 8 Pyrimido[5,4-d]Pyrimidine Impurity 1 2,4,6,8-TETRAHYDROXYPYRIMIDO-[5,4-D]PYRIMIDIN Pyrimido[5,4-d]pyrimidine-2,4,6,8(3H,7H)-tetrone, 1,5-dihydro- 2,4,6,8-Tetrahydroxy-pynmido[5,4-d]pynmidine tetratomic 6713-54-8 2,4,6,8-Tetrahydroxy-Pyrimido-(5,4D)Pyrimidine 2,4,6, 8-tetrahydroxy pyrimidine and [5, 4-D] pyrimidine 6713-54-8 Heterocycle-Pyrimidine series