Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>HA 130

HA 130

HA 130 Structure
HA 130 structure
CAS No.
1229652-21-4
Chemical Name:
HA 130
Synonyms
HA 150;HA 130;CS-1606;HA130 (HA-130);HA130;HA-130;HA 130;HA130 (Autotaxin Inhibitor);inhibit,HA 130,HA130,Phosphodiesterase (PDE),Inhibitor,HA-130;(Z)-3-((4-((3-(4-fluorobenzyl)-2,4-dioxothiazolidin-5-ylidene)methyl)phenoxy)methyl)phenylboronic acid;B-[3-[[4-[[3-[(4-Fluorophenyl)Methyl]-2,4-dioxo-5-thiazolidinylidene]Methyl]phenoxy]Methyl]phenyl]boronic Acid;Boronic acid, B-[3-[[4-[[3-[(4-fluorophenyl)methyl]-2,4-dioxo-5-thiazolidinylidene]methyl]phenoxy]methyl]phenyl]-
CBNumber:
CB62546788
Molecular Formula:
C24H19BFNO5S
Molecular Weight:
463.29
MDL Number:
MFCD20926343
MOL File:
1229652-21-4.mol
MSDS File:
SDS
Last updated:2023-06-30 15:45:59
Request For Quotation

HA 130 Properties

storage temp. Store at -20°C
solubility DMF:10.0(Max Conc. mg/mL);21.58(Max Conc. mM)
DMSO:30.11(Max Conc. mg/mL);64.99(Max Conc. mM)
Ethanol:0.5(Max Conc. mg/mL);1.08(Max Conc. mM)
form Powder

HA 130 price More Price(25)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 10498 HA-130 ≥98% 1229652-21-4 5mg $72 2024-03-01 Buy
Cayman Chemical 10498 HA-130 ≥98% 1229652-21-4 10mg $129 2024-03-01 Buy
Cayman Chemical 10498 HA-130 ≥98% 1229652-21-4 25mg $178 2024-03-01 Buy
Tocris 4196 HA130 ≥98%(HPLC) 1229652-21-4 10 $225 2021-12-16 Buy
Tocris 4196 HA130 ≥98%(HPLC) 1229652-21-4 50 $927 2021-12-16 Buy
Product number Packaging Price Buy
10498 5mg $72 Buy
10498 10mg $129 Buy
10498 25mg $178 Buy
4196 10 $225 Buy
4196 50 $927 Buy

HA 130 Chemical Properties,Uses,Production

Uses

HA130 is a selective boronic acid-based inhibitor of autotaxin. Studies show that adminstration of HA130 in mice results in rapid decrease of the lipid mediator lysophosphatidic acid (LPA) in the circulation. These findings suggest that HA 150 may provide useful therapeutic strategy in treating disorders associated with vascular development, inflammation, fibrotic disease, and tumor progression.

Uses

HA 150 is a selective boronic acid-based inhibitor of autotaxin. Studies show that adminstration of HA 150 in mice results in rapid decrease of the lipid mediator lysophosphatidic acid (LPA) in the circulation. These findings suggest that HA 150 may provide useful therapeutic strategy in treating disorders associated with vascular development, inflammation, fibrotic disease, and tumor progression.

storage

Store at -20°C

HA 130 synthesis

1229652-27-0
137660-67-4
1229652-21-4
Synthesis of HA 130 from 3-((4-formylphenoxy)methyl)phenylboronic acid and 3-(4-fluorobenzyl)thiazolidine-2,4-dione

HA 130 Preparation Products And Raw materials

Raw materials

Preparation Products

HA 130 Suppliers

Global( 76)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32480 60
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Career Henan Chemica Co 		+86-0371-86658258 15093356674; laboratory@coreychem.com China 30255 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
InvivoChem 		+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		13417589054 trendseenbio@gmail.com China 11681 58
LEAPCHEM CO., LTD. 		+86-852-30606658 market18@leapchem.com China 43348 58
Jilin Chinese Academy of Sciences-yanshen Technology 		+undefined18143011203 info@chemextension.com China 42057 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 52927 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131981 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
TargetMol Chemicals Inc. 		58
Career Henan Chemica Co 		58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		58
InvivoChem 		58
ShenZhen Trendseen Biological Technology Co.,Ltd. 		58
LEAPCHEM CO., LTD. 		58
Jilin Chinese Academy of Sciences-yanshen Technology 		58
Aladdin Scientific 		58
Amadis Chemical Company Limited 		58
B-[3-[[4-[[3-[(4-Fluorophenyl)Methyl]-2,4-dioxo-5-thiazolidinylidene]Methyl]phenoxy]Methyl]phenyl]boronic Acid HA130 (Autotaxin Inhibitor) HA 130 HA 150 HA130 (HA-130) (Z)-3-((4-((3-(4-fluorobenzyl)-2,4-dioxothiazolidin-5-ylidene)methyl)phenoxy)methyl)phenylboronic acid CS-1606 HA130;HA-130;HA 130 Boronic acid, B-[3-[[4-[[3-[(4-fluorophenyl)methyl]-2,4-dioxo-5-thiazolidinylidene]methyl]phenoxy]methyl]phenyl]- inhibit,HA 130,HA130,Phosphodiesterase (PDE),Inhibitor,HA-130 [4-[[4-[(Z)-[3-[(4-fluorophenyl)methyl]-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl]phenoxy]methyl]phenyl]boronic acid 1229652-21-4 Aromatics, Boron Derivatives, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals Aromatics Boron Derivatives Heterocycles Inhibitors Intermediates & Fine Chemicals Pharmaceuticals Selective autotaxin inhibitor.