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ChemicalBook CAS DataBase List HA 130

HA 130 synthesis

1synthesis methods
1229652-27-0 Synthesis
3-((4-formylphenoxy)methyl)phenylboronic acid

1229652-27-0
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137660-67-4 Synthesis
3-(4-fluorobenzyl)thiazolidine-2,4-dione

137660-67-4
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Yield: 64%

Reaction Conditions:

with piperidine in ethanol for 22 h;Reflux;

References:

Albers, Harald M. H. G.;Van Meeteren, Laurens A.;Egan, David A.;Van Tilburg, Erica W.;Moolenaar, Wouter H.;Ovaa, Huib [Journal of Medicinal Chemistry,2010,vol. 53,# 13,p. 4958 - 4967] Location in patent:experimental part