BUTACAINE
- CAS No.
- 149-16-6
- Chemical Name:
- BUTACAINE
- Synonyms
- Butyn;BUTACAINE;PHENBUTACAINE;Dibutylaminopropyl-p-aminobenzoate;p-Aminobenzoyldibutylaminopropanol;3-dibutylaminopropylp-aminobenzoate;3-Dibutylaminopropyl p-aminobenzoate;3-(Dibutylamino)propyl 4-aminobenzoate;3-(dibutylamino)propyl 4-azanylbenzoate;3-(dibutylamino)-1-propanolp-aminobenzoate
- CBNumber:
- CB6261717
- Molecular Formula:
- C18H30N2O2
- Molecular Weight:
- 306.44
- MDL Number:
- MFCD00056117
- MOL File:
- 149-16-6.mol
| Melting point | 25°C |
|---|---|
| Boiling point | bp0.11 178-182° |
| Density | 1.0593 (rough estimate) |
| refractive index | 1.5700 (estimate) |
| storage temp. | −20°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | pKa 8.96 (Uncertain) |
| form | Solid |
| color | White to Pale Orange |
| Stability | Light Sensitive |
| EWG's Food Scores | 1 |
| FDA UNII | Z84S23CGJJ |
| EPA Substance Registry System | Butacaine (149-16-6) |
SAFETY
Risk and Safety Statements
| RIDADR | 3249 |
|---|---|
| WGK Germany | 3 |
| RTECS | UB0875000 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
BUTACAINE price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | B694295 | Butacaine | 149-16-6 | 1g | $220 | 2021-12-16 | Buy |
| TRC | B694295 | Butacaine | 149-16-6 | 2.5g | $440 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0015124 | BUTACAINE 95.00% | 149-16-6 | 10MG | $255.15 | 2021-12-16 | Buy |
| Crysdot | CD31003361 | Butacaine 98+% | 149-16-6 | 100mg | $42 | 2021-12-16 | Buy |
BUTACAINE Chemical Properties,Uses,Production
Originator
Butelline,ALK-Abello
Uses
radioopaque agent
Uses
Butacaine is an human glutathione transferase P1-1 (GST P1-1).
Definition
ChEBI: 4-aminobenzoic acid 3-(dibutylamino)propyl ester is a benzoate ester.
Manufacturing Process
40 g p-nitro-gamma-bromo-propylbenzoate and 40 g dibutylamine are heated
together at 60°C, for four hours. The excess dibutyl amine is removed by
washing the product with water and then steam distilling the residue. The
material remaining in the flask is taken up in benzene and treated with
aqueous hydrochloric acid. Part of the p-nitrobenzoyl-gamma-di-nbutylamminopropanol
hydrochloride thus formed goes into the water layer,
while most of it separates as a heavy oily layer. This, together with the water
layer, is separated from the benzene layer, made alkaline, and the resulting
base taken up in benzene. Upon removal of the solvent, the desired pnitrobenzoyl-
gamma-di-n-butylamminopropanol is obtained.
The p-nitrobenzoyl-gamma-di-n-butylamminopropanol is reduced by warming
to about 60°C with an excess of iron filings and a small amount of
hydrochloric acid for four hours. The material is then allowed to cool,
neutralized with dilute sodium hydroxide solution, and extracted with ether.
Upon the removal of the ether, the free base, para-aminobenzoyl-gamma-din-
butylaminopropanol, remains behind as an oil. It is exactly neutralized with
aqueous hydrochloric acid and the resulting solid salt purified by
recrystallization from water or a suitable organic solvent. It melts at 151°-
152°C (corr.) after drying at 100°C.
brand name
Butyn (Abbott).
Therapeutic Function
Local anesthetic
BUTACAINE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4863 | 58 |
| Shanghai TaoSu Biochemical Technology Co., Ltd. | 021-33632979 | info@tsbiochem.com | China | 8073 | 58 |
| Musechem | +1-800-259-7612 | info@musechem.com | United States | 4662 | 60 |
| Aikon International Limited | 025-58851090 13611564524 | lwan@aikonchem.com | China | 15952 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |