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Carboxyatractyloside

Carboxyatractyloside structure

CAS No.: 77228-71-8

Chemical Name:: Carboxyatractyloside

Synonyms: Carboxyatractylosidetripotassiumsal;Carboxyatractyloside tripotassium salt;Kaur-16-ene-18,19-dioic acid, 15-hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-β-D-glucopyranosyl]oxy]-, (2β,15α)-;Kaur-16-ene-18,19-dioic acid, 15-hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-β-D-glucopyranosyl]oxy]-, (2β,15α)-;(2beta,15alpha)-15-Hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-beta-D-glucopyranosyl]oxy]kaur-16-ene-18,19-dioic acid

CBNumber:: CB62677293

Molecular Formula:: C31H46O18S2

Molecular Weight:: 770.81

MDL Number:: MFCD00152201

MOL File:: 77228-71-8.mol

Last updated:2023-04-23 13:52:06

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Carboxyatractyloside Properties

Density	1.58±0.1 g/cm3(Predicted)
storage temp.	-20°C
solubility	H2O: ≥10mg/mL
pka	-3?+-.0.18(Predicted)
form	solid
color	white

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS06
Signal word	Danger
Hazard statements	H301+H311+H331
Precautionary statements	P261-P264-P280-P301+P310-P302+P352+P312-P304+P340+P311
Hazard Codes	T
Risk Statements	23/24/25
Safety Statements	36/37-45
RIDADR	UN 2811 6.1 / PGI
WGK Germany	3

Carboxyatractyloside price More Price(14)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	C4992	Carboxyatractyloside potassium salt ≥98% (HPLC), from	77228-71-8	2mg	$199	2023-01-07	Buy
ChemScene	CS-0017047	Carboxyatractyloside	77228-71-8	5mg	$250	2021-12-16	Buy
AvaChem	3202A	Carboxyatractyloside	77228-71-8	10mg	$290	2021-12-16	Buy
Arctom	AS713545	Carboxyatractyloside ≥98%	77228-71-8	100mg	$342	2021-12-16	Buy
Crysdot	CD11059260	Carboxyatractylosidetripotassiumsalt 97%	77228-71-8	10mg	$380	2021-12-16	Buy

Product number	Packaging	Price	Buy
C4992	2mg	$199	Buy
CS-0017047	5mg	$250	Buy
3202A	10mg	$290	Buy
AS713545	100mg	$342	Buy
CD11059260	10mg	$380	Buy

Carboxyatractyloside Chemical Properties,Uses,Production

Uses

Carboxyatractyloside potassium salt has been used as an activator of Ca²⁺-induced mPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) opening. It has also been used as a adenine nucleotide translocator (ANT) inhibitor to study the inhibition of oxidative phosphorylation in intact T98G glioma cells.

Biochem/physiol Actions

Carboxyatractyloside is a highly selective inhibitor of cytosolic side-specific mitochondrial ADP/ATP carrier; i.e. adenine nucleotide translocase (ANT); causes stabilization of the c conformation of ANT leading to permeability transition pore (PTP) opening, loss of mitochondrial membrane potential, and apoptosis.

target

Calcium Channel | P450 (e.g. CYP17)

Carboxyatractyloside Preparation Products And Raw materials

Raw materials

Preparation Products

Carboxyatractyloside Suppliers

Global( 122)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3620	58
Chengdu Greenpure Biopharma CO.,Ltd	18283602253	jancyzheng@gcgreenpure.com	China	952	58
Chengdu GLP biotechnology Co Ltd	028-87075086 13350802083	scglp@glp-china.com	CHINA	1824	58
Chengdu Biopurify Phytochemicals Ltd.	+8618080483897	sales@biopurify.com	China	3424	58
Xi'an Kono chem co., Ltd.,	029-86107037 13289246953	info@konochemical.com	China	2995	58
Shaanxi Pioneer Biotech Co., Ltd .	+8613259417953	sales@pioneerbiotech.com	China	3000	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Shanghai Standard Technology Co., Ltd.	18502101150	ft-sales@nature-standard.com	CHINA	1923	58
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
Wuhan ChemNorm Biotech Co.,Ltd.	+86-27-8439 4403 18971486879	sales@chemnorm.com	CHINA	2935	58

Supplier	Advantage
Shanghai Zheyan Biotech Co., Ltd.	58
Chengdu Greenpure Biopharma CO.,Ltd	58
Chengdu GLP biotechnology Co Ltd	58
Chengdu Biopurify Phytochemicals Ltd.	58
Xi'an Kono chem co., Ltd.,	58
Shaanxi Pioneer Biotech Co., Ltd .	58
BOC Sciences	58
Shanghai Standard Technology Co., Ltd.	58
career henan chemical co	58
Wuhan ChemNorm Biotech Co.,Ltd.	58

View Lastest Price from Carboxyatractyloside manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2023-02-24	Carboxyatractyloside Potassium Salt 77228-71-8	US $0.00 / mg	20mg	≥98%(HPLC)	10 g	Shanghai Standard Technology Co., Ltd.
	2020-01-10	Carboxyatractyloside tripotassium salt 77228-71-8	US $9.80 / KG	1KG	≥98%	20 tons	Career Henan Chemical Co

Carboxyatractyloside Potassium Salt
77228-71-8
US $0.00 / mg
≥98%(HPLC)
Shanghai Standard Technology Co., Ltd.

Carboxyatractyloside tripotassium salt
77228-71-8
US $9.80 / KG
≥98%
Career Henan Chemical Co

77228-71-8(Carboxyatractyloside)Related Search:

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Poricoic acid A(F) Pachymic acid 1,3,5-Tricaffeoylquinic acid Terrestrosin K Madecassic acid

dipotassium dihydrogen 15alpha-hydroxy-2beta-[[2-O-isovaleryl-3,4-di-O-sulphonato-beta-D-glucopyranosyl]oxy]kaur-16-ene-18,19-dioate

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(2beta,15alpha)-15-Hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-beta-D-glucopyranosyl]oxy]kaur-16-ene-18,19-dioic acid Carboxyatractyloside tripotassium salt Kaur-16-ene-18,19-dioic acid, 15-hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-β-D-glucopyranosyl]oxy]-, (2β,15α)- Carboxyatractylosidetripotassiumsal Kaur-16-ene-18,19-dioic acid, 15-hydroxy-2-[[2-O-(3-methyl-1-oxobutyl)-3,4-di-O-sulfo-β-D-glucopyranosyl]oxy]-, (2β,15α)- 77228-71-8 C31H46O18S2 reagent standard substance chemical reagent herbal extract pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM).