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bis(3',5')-cyclic diguanylic acid

bis(3',5')-cyclic diguanylic acid structure

CAS No.: 61093-23-0

Chemical Name:: bis(3',5')-cyclic diguanylic acid

Synonyms: c-di-GMP;5GP-5GP;Cyclic di-GMP;cyclic diguanylate;Cyclic-di-GMP Ammonium;Cyclic-di-GMP(c-di-GMP);CyclicdiGMP,Cyclic di GMP;Cyclic-di-GMP，cyclic diguanylate;bis(3',5')-cyclic diguanylic acid;3'-Guanylic acid, guanylyl-(3'→5')-, cyclic nucleotide

CBNumber:: CB71335661

Molecular Formula:: C20H24N10O14P2

Molecular Weight:: 690.41

MDL Number:: MFCD31563661

MOL File:: 61093-23-0.mol

MSDS File:: SDS

Last updated:2024-04-22 18:05:02

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bis(3',5')-cyclic diguanylic acid Properties

Melting point	193-196 °C (decomp)
Density	2.70±0.1 g/cm3(Predicted)
storage temp.	-20°C
form	powder
pka	0.66±0.70(Predicted)
color	white to beige
Water Solubility	Soluble in Water

bis(3',5')-cyclic diguanylic acid price More Price(10)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	SML1228	Cyclic-di-GMP sodium salt ≥98% (HPLC)	61093-23-0	1UMO	$211	2023-06-20	Buy
TRC	C987353	Cyclic-di-GMP	61093-23-0	2.5mg	$725	2021-12-16	Buy
Biosynth Carbosynth	NC46014	Cyclic diguanosine monophosphate	61093-23-0	5mg	$1200	2021-12-16	Buy
ApexBio Technology	B7839	Cyclicdi-GMP	61093-23-0	500ug	$131	2021-12-16	Buy
Biosynth Carbosynth	NC46014	Cyclic diguanosine monophosphate	61093-23-0	10mg	$2160	2021-12-16	Buy

Product number	Packaging	Price	Buy
SML1228	1UMO	$211	Buy
C987353	2.5mg	$725	Buy
NC46014	5mg	$1200	Buy
B7839	500ug	$131	Buy
NC46014	10mg	$2160	Buy

bis(3',5')-cyclic diguanylic acid Chemical Properties,Uses,Production

Uses

Cyclic-di-GMP sodium salt has been used as a quorum sensing molecule.

Definition

ChEBI: A cyclic purine dinucleotide that is the 3',5'-cyclic dimer of MP.

Biochem/physiol Actions

Cyclic-di-GMP is a naturally occurring small molecule that acts as a bacterial second messenger to regulate important signaling mechanisms in prokaryotes that control bacterial survival, adhesion, colonization, biofilm formation, and virulence factors production. During infections Cyclic-di-GMP is bound by host STING (stimulator of interferon genes) leading to expression of interferon genes, activating innate immune responses. c-di-GMP has been found in eukarotic systems acting not only in immune response, but as an inhibitor of the pacemaker I(f) current in the heart.

bis(3',5')-cyclic diguanylic acid synthesis

Synthesis of bis(3',5')-cyclic diguanylic acid from N2-Isobutyryl-2''-O-(tert-butyldimethylsilyl)-5''-O-(4,4''-dimethoxytrityl)-gu

bis(3',5')-cyclic diguanylic acid Preparation Products And Raw materials

Raw materials

N2-Isobutyryl-2''-O-(tert-butyldimethylsilyl)-5''-O-(4,4''-dimethoxytrityl)-gu

Preparation Products

bis(3',5')-cyclic diguanylic acid Suppliers

Global( 72)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hangzhou Meiya Pharmaceutical Co Ltd	+86-021-33686691 +8618001850931	sales@meiyapharm.com	China	57	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	eric@witopchemical.com	China	23556	58
NewCan Biotech Limited	+86-0571-86912261 +8613735419629	sales@newcanbio.com	China	10000	58
Alfa Chemistry	+1-5166625404	Info@alfa-chemistry.com	United States	21317	58
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	sales@chemhifuture.com	China	3136	58
Zibo Hangyu Biotechnology Development Co., Ltd	+86-0533-2185556 +8617865335152	Mandy@hangyubiotech.com	China	11013	58
R&D Scientific Inc.	+12266000236	sales@rdscientific.com	Canada	1306	58
Jilin Chinese Academy of Sciences-yanshen Technology	+undefined18143011203	info@chemextension.com	China	42057	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131981	58

Supplier	Advantage
Hangzhou Meiya Pharmaceutical Co Ltd	58
TargetMol Chemicals Inc.	58
ANHUI WITOP BIOTECH CO., LTD	58
NewCan Biotech Limited	58
Alfa Chemistry	58
Nantong HI-FUTURE Biology Co., Ltd.	58
Zibo Hangyu Biotechnology Development Co., Ltd	58
R&D Scientific Inc.	58
Jilin Chinese Academy of Sciences-yanshen Technology	58
Amadis Chemical Company Limited	58

Bis(3',5')-cyclic diguanylic Acid: Physiological Activities, Synthesis and Degradation
Bis(3',5')-cyclic diguanylic acid regulates bacterial and eukaryotic processes, synthesized by cyclases and degraded by phosph....
Apr 17，2024

The introduction of bis(3',5')-cyclic diguanylic acid
The bis(3',5')-cyclic diguanylic acid, with the CAS No: 61093-23-0, is also known as Cyclic diguanosine monophosphate (c-diGMP....
Jan 19，2023

View Lastest Price from bis(3',5')-cyclic diguanylic acid manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-04-22	Cyclic-di-GMP 61093-23-0	US $6500.00 / g	1g	96	500 Kg	R&D Scientific Inc.
	2024-03-11	Cyclic-Di-GMP, Sodium Salt 61093-23-0	US $0.00-0.00 / kg	1kg	≥95.0%	1000 kg	Hangzhou Meiya Pharmaceutical Co Ltd

Cyclic-di-GMP
61093-23-0
US $6500.00 / g
96
R&D Scientific Inc.

Cyclic-Di-GMP, Sodium Salt
61093-23-0
US $0.00-0.00 / kg
≥95.0%
Hangzhou Meiya Pharmaceutical Co Ltd

bis(3',5')-cyclic diguanylic acid Cyclic diguanosine monophosphate ( c-diGMP/c-di-GMP ) / cyclic bis ( 3' > 5' ) diguanylic acid Cyclic di-GMP 5GP-5GP Cyclic-di-GMP，cyclic diguanylate cyclic diguanylate 3'-Guanylic acid, guanylyl-(3'→5')-, cyclic nucleotide Cyclic-di-GMP(c-di-GMP) Cyclic-di-GMP Ammonium c-di-GMP CyclicdiGMP,Cyclic di GMP Bis-(3',5')-cyclic-di-guanosine monophosphate, sodium salt Cyclic diguanosine monophosphate(c-digmp/c-di-gmp)/ cyclic bis diguanylic acid 61093-23-0 C20H24N10O14P2 Nucleotide