bis(3',5')-cyclic diguanylic acid

bis(3',5')-cyclic diguanylic acid 구조식 이미지
카스 번호:
61093-23-0
상품명:
bis(3',5')-cyclic diguanylic acid
동의어(영문):
c-di-GMP;5GP-5GP;Cyclic di-GMP;cyclic diguanylate;Cyclic-di-GMP Ammonium;Cyclic-di-GMP(c-di-GMP);CyclicdiGMP,Cyclic di GMP;3',5'-Cyclic diguanylic acid;Cyclic-di-GMP,cyclic diguanylate;bis(3',5')-cyclic diguanylic acid
CBNumber:
CB71335661
분자식:
C20H24N10O14P2
포뮬러 무게:
690.41
MOL 파일:
61093-23-0.mol
MSDS 파일:
SDS

bis(3',5')-cyclic diguanylic acid 속성

녹는점
193-196 °C (decomp)
밀도
2.70±0.1 g/cm3(Predicted)
저장 조건
-20°C
물리적 상태
가루
산도 계수 (pKa)
0.66±0.70(Predicted)
색상
흰색에서 베이지색
수용성
물에 용해됨

안전

bis(3',5')-cyclic diguanylic acid C화학적 특성, 용도, 생산

용도

Cyclic-di-GMP sodium salt has been used as a quorum sensing molecule.

정의

ChEBI: A cyclic purine dinucleotide that is the 3',5'-cyclic dimer of MP.

Biochem/physiol Actions

Cyclic-di-GMP is a naturally occurring small molecule that acts as a bacterial second messenger to regulate important signaling mechanisms in prokaryotes that control bacterial survival, adhesion, colonization, biofilm formation, and virulence factors production. During infections Cyclic-di-GMP is bound by host STING (stimulator of interferon genes) leading to expression of interferon genes, activating innate immune responses. c-di-GMP has been found in eukarotic systems acting not only in immune response, but as an inhibitor of the pacemaker I(f) current in the heart.

bis(3',5')-cyclic diguanylic acid 준비 용품 및 원자재

원자재

준비 용품


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