4-Fluoro-7-nitrobenzofurazan
- CAS No.
- 29270-56-2
- Chemical Name:
- 4-Fluoro-7-nitrobenzofurazan
- Synonyms
- NBD-F;NBD FLUORIDE;4-Fluoro-7-nitro-2,1;4-FLUORO-7-NITROBENZOFURAZAN;4-FLUORO-7-NITROBENZOFUROZAN;4-Fluoro-7-nitrobenzofurazane;NITROBENZOFURAZAN, 4-FLUORO-7-;4-Fluoro-7-nitrobenzofurazan,98%;4-Fluoro-7-nitrobenzofurazan,NBD-F;NBD-F [4-Fluoro-7-nitrobenzofurazan
- CBNumber:
- CB7255542
- Molecular Formula:
- C6H2FN3O3
- Molecular Weight:
- 183.1
- MDL Number:
- MFCD00010196
- MOL File:
- 29270-56-2.mol
| Melting point | 52-54 °C(lit.) |
|---|---|
| Boiling point | 308.6±45.0 °C(Predicted) |
| Density | 1.6753 (estimate) |
| Flash point | >230 °F |
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| solubility | It is soluble in DMSO, DMF, CH3OH, CH3CN and CHCl3. |
| form | Crystalline Chunks |
| pka | -5.59±0.50(Predicted) |
| color | Brown |
| BRN | 1077571 |
| CAS DataBase Reference | 29270-56-2(CAS DataBase Reference) |
| FDA UNII | L5VS78SU5J |
4-Fluoro-7-nitrobenzofurazan price More Price(30)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 47140 | 4-Fluoro-7-nitrobenzofurazan BioReagent, suitable for fluorescence, ≥98.0% (HPLC) | 29270-56-2 | 10mg | $470 | 2024-03-01 | Buy |
| Sigma-Aldrich | 47140 | 4-Fluoro-7-nitrobenzofurazan BioReagent, suitable for fluorescence, ≥98.0% (HPLC) | 29270-56-2 | 50mg | $1920 | 2024-03-01 | Buy |
| TCI Chemical | A5593 | NBD-F (=4-Fluoro-7-nitro-2,1,3-benzoxadiazole)[for HPLC Labeling] >99.0%(HPLC) | 29270-56-2 | 100mg | $228 | 2024-03-01 | Buy |
| Alfa Aesar | J61336 | 4-Fluoro-7-nitrobenzofurazan | 29270-56-2 | 100mg | $508 | 2024-03-01 | Buy |
| Sigma-Aldrich | F5883 | 4-Fluoro-7-nitrobenzofurazan ≥98% (elemental analysis) | 29270-56-2 | 5mg | $288 | 2024-03-01 | Buy |
4-Fluoro-7-nitrobenzofurazan Chemical Properties,Uses,Production
Chemical Properties
BROWN CRYSTALLINE CHUNKS
Uses
A fluorescence reagent
Uses
4-Chloro-7-nitrobenzofurazan (NBD-chloride) was used in the following studies, Synthesis of fluorescent phospholipid-derivative, NBD-didecanoylphosphatidylethanolamine, Synthesis of functionalized hydroxynaphthofurazan, Spectrophotometric and spectrofluorometric determination of clemastine hydrogen fumarate, loratadine, losartan potassium and ramipril in pharmaceutical formulations. Synthesis of 7-nitrobenzofurazan (NBD)-labeled maleimide, via Diels-Alder reaction. NBD-Cl is widely used to label peptides, proteins, drugs and other biomolecules. It is also a popular derivatizing reagent for HPLC analysis
Purification Methods
Purify it by repeated recrystallisation from pet ether (b 40-60o). On treatment with MeONa in MeOH it gives 4-methoxy-7-nitrobenzo-2-oxa-1,3-diazole m 115-116o. [Nunno et al. J Chem Soc (C) 1433 1970.] It is a very good fluorophore for amino acids [Imai & Watanabe Analyt Chim Acta 130 377 1981], as it reacts with primary and secondary amines to form fluorescent adducts with 470nm and 530nm. It gives a glycine derivative with m 185-187o [Miyano et al. Anal Chim ex em Acta 170 81 1985]. 5-Fluorouracil (5 -fluoropyrimidinedi -2,4 -[1 H ,3 H ]-one) [51 -21 -8] M 130.1, m 282 -2 8 3o(dec), 282-286o(dec), pK 1 8.04, pK 2 13.0. Recrystallise it from H2O or MeOH/Et2O and sublime it at 190-200o/0.1mm or 210-230o/0.5mm. UV: at 265-266nm ( 7070). [Barton et al. J Org max Chem 37 329 1972, Duschinsky & Pleven J Am Chem Soc 79 4559 1957, Beilstein 24 III/IV 1229.]
4-Fluoro-7-nitrobenzofurazan Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 12551 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
| CD Chemical Group Limited | +8615986615575 | info@codchem.com | China | 20356 | 58 |
| Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
View Lastest Price from 4-Fluoro-7-nitrobenzofurazan manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-02 | 4-fluoro-7-nitro-2,1,3-benzoxadiazole
29270-56-2
|
US $0.00 / g | 1g | >95.00% | 1g | Xian confluore Biological Technology Co., Ltd. | |
 |
2019-07-06 | 4-Fluoro-7-nitrobenzofurazan
29270-56-2
|
US $2.00 / kg | 1kg | 9% | 100kg | Career Henan Chemical Co |
-
- 4-fluoro-7-nitro-2,1,3-benzoxadiazole
29270-56-2
- US $0.00 / g
- >95.00%
- Xian confluore Biological Technology Co., Ltd.
-
- 4-Fluoro-7-nitrobenzofurazan
29270-56-2
- US $2.00 / kg
- 9%
- Career Henan Chemical Co
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