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EzetiMibe-d4

EzetiMibe-d4 structure

CAS No.: 1093659-89-2

Chemical Name:: EzetiMibe-d4

Synonyms: Ezetimibe-d4-1;[2H4]-Ezetimibe;Ezetimibe Impurity 119;Ezetimibe D4 (4-Fluorophenyl-2,3,5,6-d4);(3R,4S)-1-(4-fluorophenyl)-4-(4-hydroxyphenyl)-3-[(3S)-3-hydroxy-3-(2,3,5,6-tetradeuterio-4-fluorophenyl)propyl]azetidin-2-one;Ezetimibe D4Q: What is Ezetimibe D4 Q: What is the CAS Number of Ezetimibe D4 Q: What is the storage condition of Ezetimibe D4

CBNumber:: CB72710005

Molecular Formula:: C24H21F2NO3

Molecular Weight:: 409.43

MDL Number:

MOL File:: 1093659-89-2.mol

Last updated:2023-05-21 10:59:17

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EzetiMibe-d4 Properties

storage temp.	Store at -20°C
solubility	DMF: Soluble; DMSO: Soluble; Ethanol: Soluble; Methanol: Soluble
form	A solid

EzetiMibe-d4 price More Price(3)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	25044	Ezetimibe-d4 ≥99% deuterated forms (d1-d4)	1093659-89-2	1mg	$480	2024-03-01	Buy
TRC	E975003	Ezetimibe-d4	1093659-89-2	1mg	$275	2021-12-16	Buy
AK Scientific	2934DC	(3R,4S)-1-(4-Fluorophenyl)-4-(4-hydroxyphenyl)-3-[(3S)-3-hydroxy-3-(2,3,5,6-tetradeuterio-4-fluorophenyl)propyl]azetidin-2-one	1093659-89-2	1mg	$633	2021-12-16	Buy

Product number	Packaging	Price	Buy
25044	1mg	$480	Buy
E975003	1mg	$275	Buy
2934DC	1mg	$633	Buy

EzetiMibe-d4 Chemical Properties,Uses,Production

Description

Ezetimibe-d₄ is intended for use as an internal standard for the quantification of ezetimibe by GC- or LC-MS. Ezetimibe inhibits intestinal cholesterol absorption by preventing cholesterol uptake by the Niemann-Pick C1-like 1 (NPC1L1) protein, a cholesterol transporter located in the apical membrane of enterocytes. Upon oral administration ezetimibe undergoes rapid glucuronidation in the intestine where its glucuronide binds NPC1L1. Ezetimibe exhibits ED₅₀ values of 0.0005-0.05 mg/kg in various animal models, selectively blocking cholesterol absorption without inhibiting pancreatic lipolytic enzyme activities in the intestinal lumen, affecting bile acid micelle solubilization of cholesterol, or interfering with the absorption of triglycerides, fatty acids, or bile acids.

Uses

Ezetimibe-d4 is the labeled analogue of Ezetimibe (E975000), an antihyperlipoproteinemic. A cholesterol absorption inhibitor.

EzetiMibe-d4 Preparation Products And Raw materials

Raw materials

Preparation Products

EzetiMibe-d4 Suppliers

Global( 27)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32344	50
Cato Research Chemicals Inc.	020-81960175	min.he@cato-chem.com	China	1958	55
ChemStrong Scientific Co.,Ltd	0755-0755-66853366 13670046396	sales@chem-strong.com	China	17994	56
Artis Biotech Co. Ltd.	19138486554 18582380095	sales@artisbio.com	China	2862	58
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9709	58
Chengdu Novel Biomedical Co., Ltd.	028-85255396 18302801538	cdnovell@163.com	China	2244	58
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226 13028896684	sales@rrkchem.com	China	55896	58

Supplier	Advantage
BOC Sciences	58
Aladdin Scientific	58
J & K SCIENTIFIC LTD.	76
Chemsky（shanghai）International Co.,Ltd.	50
Cato Research Chemicals Inc.	55
ChemStrong Scientific Co.,Ltd	56
Artis Biotech Co. Ltd.	58
Shanghai EFE Biological Technology Co., Ltd.	58
Chengdu Novel Biomedical Co., Ltd.	58
Shenzhen Polymeri Biochemical Technology Co., Ltd.	58

1093659-89-2(EzetiMibe-d4)Related Search:

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(3R,4S)-1-(4-fluorophenyl)-4-(4-hydroxyphenyl)-3-[(3S)-3-hydroxy-3-(2,3,5,6-tetradeuterio-4-fluorophenyl)propyl]azetidin-2-one [2H4]-Ezetimibe Ezetimibe Impurity 119 Ezetimibe D4Q: What is Ezetimibe D4 Q: What is the CAS Number of Ezetimibe D4 Q: What is the storage condition of Ezetimibe D4 Ezetimibe-d4-1 Ezetimibe D4 (4-Fluorophenyl-2,3,5,6-d4) 1093659-89-2