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Evolocumab

Evolocumab structure

CAS No.: 1256937-27-5

Chemical Name:: Evolocumab

Synonyms: AMG 145;Evolocumab;Evolocumab(anti-PCSK9);Research Grade Evolocumab(DHJ24002);AMG-145,Ser/Thr Protease,Repatha,AMG 145,inhibit,atherosclerotic cardiovascular disease,Serine endopeptidases,PCSK9,Evolocumab,AMG145,Threonine proteases,hypercholesterolemia,LDLR,Inhibitor,Serine proteases

CBNumber:: CB72744219

Molecular Formula:

Molecular Weight:: 0

MDL Number:

MOL File:: Mol file

Last updated:2023-05-21 10:59:17

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Evolocumab Properties

storage temp.	Store at 4°C, protect from light
FDA UNII	LKC0U3A8NJ
ATC code	C10AX13

Pharmacokinetic data

Excreted unchanged in urine	Minimal
Volume of distribution	0.5 Litres
Biological half-life	11-17 days / Unchanged

Evolocumab price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Biosynth Carbosynth	BE165589	Evolocumab - solution - 5 mg/ml	1256937-27-5	1mg	$550	2021-12-16	Buy
DC Chemicals	013344	Evolocumab	1256937-27-5	002	$750	2021-12-16	Buy

Product number	Packaging	Price	Buy
BE165589	1mg	$550	Buy
013344	002	$750	Buy

Evolocumab Chemical Properties,Uses,Production

Clinical Use

IgG2 monoclonal antibody:
Treatment of hypercholesterolaemia, mixed dyslipidaemia and homozygous familial hypercholesterolaemia

Drug interactions

Potentially hazardous interactions with other drugs
Antipsychotics: avoid with clozapine - increased risk
of agranulocytosis. Vaccines: avoid concomitant use with live vaccines.

Metabolism

Evolocumab is composed of amino acids and carbohydrates as native immunoglobulin and is unlikely to be eliminated via hepatic metabolic mechanisms. Its metabolism and elimination are expected to follow the immunoglobulin clearance pathways, resulting in degradation to small peptides and individual amino acids.

Evolocumab Preparation Products And Raw materials

Raw materials

Preparation Products

Evolocumab Suppliers

Global( 55)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hubei Ipure Biology Co., Ltd	+8613367258412	ada@ipurechemical.com	China	10326	58
Career Henan Chemica Co	+86-0371-86658258 15093356674;	laboratory@coreychem.com	China	30255	58
HONG KONG IPURE BIOLOGY CO.,LIMITED	86 18062405514 18062405514	ada@ipurechemical.com	CHINA	3465	58
Shanghai Minbiotech Co., Ltd.	+8617315815539	sales@minbiotech.com	CHINA	129	58
AFINE CHEMICALS LIMITED	0571-85134551	info@afinechem.com	CHINA	15377	58
Baoji Guokang Healthchem co.,ltd	+8615604608665 15604608665	dominicguo@gk-bio.com	CHINA	9427	58
Hefei Hirisun Pharmatech Co., Ltd	+8615056975894	shawn@hirisunpharm.com	CHINA	9923	58
Nantong HI-FUTURE Biology Co., Ltd.	+undefined18051384581	sales@chemhifuture.com	China	3136	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58

Supplier	Advantage
Hubei Ipure Biology Co., Ltd	58
Career Henan Chemica Co	58
HONG KONG IPURE BIOLOGY CO.,LIMITED	58
Shanghai Minbiotech Co., Ltd.	58
AFINE CHEMICALS LIMITED	58
Baoji Guokang Healthchem co.,ltd	58
Hefei Hirisun Pharmatech Co., Ltd	58
Nantong HI-FUTURE Biology Co., Ltd.	58
TargetMol Chemicals Inc.	58
Wuhan Topule Biopharmaceutical Co., Ltd	58

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Evolocumab AMG 145 Research Grade Evolocumab(DHJ24002) AMG-145,Ser/Thr Protease,Repatha,AMG 145,inhibit,atherosclerotic cardiovascular disease,Serine endopeptidases,PCSK9,Evolocumab,AMG145,Threonine proteases,hypercholesterolemia,LDLR,Inhibitor,Serine proteases Evolocumab(anti-PCSK9) 1256937-27-5