4-Nitrobenzenesulfonyl chloride
- CAS No.
- 98-74-8
- Chemical Name:
- 4-Nitrobenzenesulfonyl chloride
- Synonyms
- NsCl;4-NITROBENZENE-1-SULFONYL CHLORIDE;P-NITROBENZENESULFONYL CHLORIDE;p-Nitrophenylsulfonyl chloride;Nosylchloride;4-NitrobenzenesuL;4-Nitrobenzenesulfon;nosyl ch202-697-9loride;4-Nitrophenylsulfonylchloride;4-Nitrophenylsulfonyl chloride
- CBNumber:
- CB7298161
- Molecular Formula:
- C6H4ClNO4S
- Molecular Weight:
- 221.62
- MDL Number:
- MFCD00007445
- MOL File:
- 98-74-8.mol
- MSDS File:
- SDS
Melting point | 75 °C |
---|---|
Boiling point | 143-144 °C (1.5002 mmHg) |
Density | 1.602 (estimate) |
vapor pressure | 0.009Pa at 20℃ |
refractive index | 1.6000 (estimate) |
Flash point | 143-144°C/1.5mm |
storage temp. | Store below +30°C. |
solubility | soluble in Toluene |
form | Powder |
color | yellow |
PH | 1 (H2O, 20℃) |
Water Solubility | Insoluble |
Sensitive | Moisture Sensitive |
BRN | 746543 |
Stability | Moisture Sensitive |
LogP | 2.1 at 20℃ |
CAS DataBase Reference | 98-74-8(CAS DataBase Reference) |
FDA UNII | ZU5JD6BHB3 |
NIST Chemistry Reference | 4-Nitrobenzenesulphonyl chloride(98-74-8) |
EPA Substance Registry System | Benzenesulfonyl chloride, 4-nitro- (98-74-8) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS05,GHS07,GHS08 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Danger | |||||||||
Hazard statements | H317-H318-H361f | |||||||||
Precautionary statements | P202-P261-P280-P302+P352-P305+P351+P338-P308+P313 | |||||||||
Hazard Codes | C | |||||||||
Risk Statements | 34-52/53 | |||||||||
Safety Statements | 26-36/37/39-45-61 | |||||||||
RIDADR | UN 3261 8/PG 2 | |||||||||
WGK Germany | 3 | |||||||||
F | 21 | |||||||||
Hazard Note | Corrosive/Moisture Sensitive | |||||||||
TSCA | Yes | |||||||||
HazardClass | 8 | |||||||||
PackingGroup | II | |||||||||
HS Code | 29049085 | |||||||||
NFPA 704 |
|
4-Nitrobenzenesulfonyl chloride price More Price(36)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 272248 | 4-Nitrobenzenesulfonyl chloride 97% | 98-74-8 | 5g | $36.4 | 2024-03-01 | Buy |
Sigma-Aldrich | 170925 | 4-Nitrobenzenesulfonyl chloride technical grade, 90% | 98-74-8 | 25g | $33.78 | 2024-03-01 | Buy |
TCI Chemical | N0144 | 4-Nitrobenzenesulfonyl Chloride >98.0%(GC)(T) | 98-74-8 | 5g | $16 | 2024-03-01 | Buy |
TCI Chemical | N0144 | 4-Nitrobenzenesulfonyl Chloride >98.0%(GC)(T) | 98-74-8 | 25g | $43 | 2024-03-01 | Buy |
Alfa Aesar | A18512 | 4-Nitrobenzenesulfonyl chloride, 97% | 98-74-8 | 25g | $71.5 | 2024-03-01 | Buy |
4-Nitrobenzenesulfonyl chloride Chemical Properties,Uses,Production
Chemical Properties
yellow to brown powder
Uses
4-Nitrobenzenesulfonyl chloride was used in the synthesis of
- [Cu(bipy)2Cl](nbs) (1) (bipy = 2,2′-bipyridine, nbs = 4-nitrobenzenesulfonate)
- hydroxylamines of sulfadiazine and sulfamethoxazole
- solution phase peptide using N-nosyl-α-amino acids.
Uses
4-Nitrobenzenesulfonyl chloride is used as an intermediate for the synthesis of pharmaceuticals like foscmprenavir, darunavir and amprenavir. It is involved in the preparation of N-nosyl-alpha-amino acid for peptide synthesis. It is also used for stereoselective α-glucosylation of partially protected carbohydrates in association with silver tri-fluoromethanesulfonate, N,N-dimethylacetamide and triethylamine. It is widely used for the synthesis of hydroxylamines of sulfadiazine, sulfamethoxazole and [Cu(bipy)2Cl](nbs) (1) (bipy = 2,2'-bipyridine, nbs = 4-nitrobenzenesulfonate).
Uses
4-Nitrobenzenesulfonyl Chloride is used in the preparation of N-Nosyl-α-amino acid for peptide synthesis.
Production Methods
4,4'-Dinitrodiphenyldisulfide [100-32-3], produced by reaction of 4-chloronitrobenzene with sodium disulfide, is treated with chlorine in HCl – HNO3 by a process similar to that used for 2-nitrobenzenesulfonyl chloride.
Flammability and Explosibility
Not classified
4-Nitrobenzenesulfonyl chloride Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Firsky International Trade (Wuhan) Co., Ltd | +8615387054039 | admin@firsky-cn.com | China | 436 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20293 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21667 | 55 |
SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2931 | 58 |
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49392 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29823 | 58 |
Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10297 | 58 |
Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9641 | 58 |
View Lastest Price from 4-Nitrobenzenesulfonyl chloride manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2023-12-26 | 4-Nitrobenzenesulfonyl chloride
98-74-8
|
US $100.00-1.00 / KG | 1KG | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | ||
2023-10-09 | 4-Nitrobenzenesulfonyl chloride
98-74-8
|
US $30.00 / KG | 1KG | 99% | 20T | Firsky International Trade (Wuhan) Co., Ltd | ||
2023-07-19 | 4-Nitrobenzenesulfonyl chloride
98-74-8
|
US $30.00 / KG | 1KG | 99% | 20 Tons | Wuhan wingroup Pharmaceutical Co., Ltd |
- 4-Nitrobenzenesulfonyl chloride
98-74-8
- US $100.00-1.00 / KG
- 99%
- Henan Fengda Chemical Co., Ltd
- 4-Nitrobenzenesulfonyl chloride
98-74-8
- US $30.00 / KG
- 99%
- Firsky International Trade (Wuhan) Co., Ltd
- 4-Nitrobenzenesulfonyl chloride
98-74-8
- US $30.00 / KG
- 99%
- Wuhan wingroup Pharmaceutical Co., Ltd
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