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Pirarubicin

Pirarubicin structure

CAS No.: 72496-41-4

Chemical Name:: Pirarubicin

Synonyms: Therarubicin;PIRARUBICIN HYDROCHLORIDE;(8S,10S)-10-[(2S,4S,5S,6S)-4-Amino-6-methyl-5-[(2S)-oxan-2-yl]oxy-oxan-2-yl]oxy-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione;(8S,10S)-10-[[3-Amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-a-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione;1609rb;CS-702;THP-ADM;Pirabucin;Pirarubcin;THEPRUBICIN

CBNumber:: CB7315796

Molecular Formula:: C32H37NO12

Molecular Weight:: 627.64

MDL Number:: MFCD00869742

MOL File:: 72496-41-4.mol

MSDS File:: SDS

Last updated:2023-07-03 17:51:04

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Pirarubicin Properties

Melting point	188-192°C (dec.)
alpha	D25 +175 ±25° (c = 0.2 in CHCl3)
Boiling point	834.7±65.0 °C(Predicted)
Density	1.51±0.1 g/cm3(Predicted)
storage temp.	2-8°C
solubility	ethanol: soluble25mg/mL
form	powder
pka	7.35±0.60(Predicted)
color	Orange to Red
Stability	Hygroscopic
FDA UNII	D58G680W0G
NCI Drug Dictionary	pirarubicin
ATC code	L01DB08

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS08
Signal word	Danger
Hazard statements	H340-H350-H360FD
Precautionary statements	P201-P202-P280-P308+P313-P405-P501
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-37/39
WGK Germany	3
RTECS	QI9296000
Toxicity	LD50 i.v. in mice: 27.8 mg/kg (Umezawa, 1979)

Pirarubicin price More Price(24)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	P8624	Pirarubicin ≥95% (HPLC)	72496-41-4	10mg	$432	2023-06-20	Buy
Sigma-Aldrich	P8624	Pirarubicin ≥95% (HPLC)	72496-41-4	25mg	$863	2023-06-20	Buy
Cayman Chemical	28384	Pirarubicin	72496-41-4	10mg	$84	2024-03-01	Buy
Cayman Chemical	28384	Pirarubicin	72496-41-4	100mg	$638	2024-03-01	Buy
Cayman Chemical	28384	Pirarubicin	72496-41-4	5mg	$44	2024-03-01	Buy

Product number	Packaging	Price	Buy
P8624	10mg	$432	Buy
P8624	25mg	$863	Buy
28384	10mg	$84	Buy
28384	100mg	$638	Buy
28384	5mg	$44	Buy

Pirarubicin Chemical Properties,Uses,Production

Description

Pirarubicin is a new anthracycline anticancer agent structurally related to doxorubicin. In acute leukemia, non-Hodgkin’s lymphoma, breast and ovariail carcinoma, pirarubicin is reportedly superior to doxorubicin and better tolerated. Its major side-effect appears to be myelosuppression, mainly in the form of leucopenia, which is potentially dose-limiting.

Chemical Properties

Red Solid

Originator

Meiji Seika (Japan)

Uses

Structural analog of Doxorubicin. Antineoplastic.

Definition

ChEBI: (7S,9S)-7-[[(2R,4S,5S,6S)-4-amino-6-methyl-5-[[(2R)-2-oxanyl]oxy]-2-oxanyl]oxy]-6,9,11-trihydroxy-9-(2-hydroxy-1-oxoethyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione is an anthracycline.

brand name

Pinorubicin; Therarubucin

Pirarubicin Preparation Products And Raw materials

Raw materials

Doxorubicin hydrochloride Adriamycin Silica gel Tetrahydropyran

Preparation Products

Pirarubicin Suppliers

Global( 264)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12456	58
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Biochempartner	0086-13720134139	candy@biochempartner.com	CHINA	967	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Hebei Guanlang Biotechnology Co., Ltd.	+86-19930503282	alice@crovellbio.com	China	8823	58
Xiamen AmoyChem Co., Ltd	+86-592-6051114 +8618959220845	sales@amoychem.com	China	6387	58
HubeiwidelychemicaltechnologyCo.,Ltd	18627774460	faith@widelychemical.com	CHINA	742	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58

Supplier	Advantage
Hebei Mojin Biotechnology Co., Ltd	58
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Biochempartner	58
Hubei Jusheng Technology Co.,Ltd.	58
Hebei Guanlang Biotechnology Co., Ltd.	58
Xiamen AmoyChem Co., Ltd	58
HubeiwidelychemicaltechnologyCo.,Ltd	58
Hubei xin bonus chemical co. LTD	58
BOC Sciences	58

View Lastest Price from Pirarubicin manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2023-07-04	Pirarubicin 72496-41-4	US $0.00 / KG	1KG	99%	50000KG/month	Hebei Mojin Biotechnology Co., Ltd
2021-12-14	Pirarubicin 72496-41-4	US $10.00 / g/Bag	10g	99	100KG	Wuhan Demeikai Biotechnology Co., Ltd
2021-07-13	Pirarubicin 72496-41-4	US $15.00-10.00 / KG	1KG	99%+ HPLC	Monthly supply of 1 ton	Zhuozhou Wenxi import and Export Co., Ltd

Pirarubicin
72496-41-4
US $0.00 / KG
99%
Hebei Mojin Biotechnology Co., Ltd

Pirarubicin
72496-41-4
US $10.00 / g/Bag
99
Wuhan Demeikai Biotechnology Co., Ltd

Pirarubicin
72496-41-4
US $15.00-10.00 / KG
99%+ HPLC
Zhuozhou Wenxi import and Export Co., Ltd

Pirarubicin Spectrum

Pirarubicin(72496-41-4)MS

72496-41-4(Pirarubicin)Related Search:

Doxorubicinone Chrysophanic acid Idarubicin hydrochloride Adriamycin 2-(HYDROXYMETHYL)ANTHRAQUINONE

Pirarubicin 1,8-Dihydroxyanthraquinone 1,2,3,4-TETRAHYDRO-1,5-NAPHTHALENEDIOL 3,4-DIMETHYL-3'-METHOXYBENZOPHENONE 2-METHOXY-4'-METHYLBENZOPHENONE

2-METHOXY-3'-METHYLBENZOPHENONE 14-Hydroxy Carminomycin 2,4-DIMETHYL-3'-METHOXYBENZOPHENONE Carubicin 4-ETHYL-2'-METHOXYBENZOPHENONE

L-DaunosamineHCl 3-METHOXY-3'-METHYLBENZOPHENONE ISLANDICIN

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THP-ADM THEPRUBICIN (8s-cis)-droxyacetyl)-1-methoxy Tepirubicin Therarubiein THP-adriamycin 5,12-Naphthacenedione, 10-((3-amino-2,3,6-trideoxy-4-O-(tetrahydro-2H-pyran-2-yl)-alpha-L- lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S-cis)- (8S)-10α-[[3-Amino-2,3,6-trideoxy-4-O-(tetrahydro-2H-pyran-2-yl)-α-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8β-(hydroxyacetyl)-1-methoxy-5,12-naphthacenedione (8S,10S)-10α-[[3-Amino-4-O-(tetrahydro-2H-pyran-2-yl)-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8β-hydroxyacetyl-1-methoxy-5,12-naphthacenedione Pirarubicin(THP-AdriaMycin) (7S,9S)-7-((2R,4S,5S,6S)-4-amino-6-methyl-5-((R)-tetrahydro-2H-pyran-2-yloxy)-tetrahydro-2H-pyran-2-yloxy)-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione PIRARUBICIN 1609rb 4’-o-tetrahydropyranyladriamycin 4’-o-tetrahydropyranyldoxorubicin 5,12-naphthacenedione,10-((3-amino-2,3,6-trideoxy-4-o-(tetrahydro-2h-pyran-2-y l)-alpha-l-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hy Pirarubicin(BICINS) (8S,10S)-10-[[3-Amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-α-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione Pinorubicin Pirabucin 5,12-Naphthacenedione, 10-3-amino-2,3,6-trideoxy-4-O-(2R)-tetrahydro-2H-pyran-2-yl-.alpha.-L-lyxo-hexopyranosyloxy-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S,10S)- (8S)-10-[(2S,4S,5S,6S)-4-amino-6-methyl-5-[(2R)-oxan-2-yl]oxy-oxan-2-yl]oxy-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione CS-702 Pirarubcin 5,12-Naphthacenedione, 10-[[3-amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-α-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-, (8S,10S)- Pirarubicin USP/EP/BP (8S,10S)-10-(((2R,4S,5S,6S)-4-Amino-6-methyl-5-(((R)-tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione PIRARUBICIN HYDROCHLORIDE Therarubicin (8S,10S)-10-[[3-Amino-2,3,6-trideoxy-4-O-[(2R)-tetrahydro-2H-pyran-2-yl]-a-L-lyxo-hexopyranosyl]oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-5,12-naphthacenedione (8S,10S)-10-[(2S,4S,5S,6S)-4-Amino-6-methyl-5-[(2S)-oxan-2-yl]oxy-oxan-2-yl]oxy-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-9,10-dihydro-7H-tetracene-5,12-dione Pirarubicin Topoisomerase II inhibitor ab142734 Famoxadone Impurity 14 THP-Doxorubicin 72496-41-4 C32H37NO12 Inhibitors API Intermediates & Fine Chemicals Pharmaceuticals Chiral Reagents