ChemicalBook >> CAS DataBase List >>ISOGUVACINE HYDROCHLORIDE
ISOGUVACINE HYDROCHLORIDE
- CAS No.
- 64603-90-3
- Chemical Name:
- ISOGUVACINE HYDROCHLORIDE
- Synonyms
- C13694;isoguvacine;ISOGUVACINE HCL;Isoguvacine hydrochl;ISOGUVACINE HYDROCHLORIDE;1,2,3,6-tetrahydro-4-Pyridinecarboxylic acid;ISOGUVACINE HYDROCHLORIDE ISO 9001：2015 REACH;4-Pyridinecarboxylic acid, 1,2,3,6-tetrahydro-;1,2,3,6-TETRAHYDRO-4-PYRIDINECARBOXYLIC ACID HYDROCHLORIDE;1,2,3,6-TETRAHYDRO-PYRIDINE-4-CARBOXYLIC ACIDHYDROCHLORIDE
- CBNumber:
- CB7406481
- Molecular Formula:
- C6H9NO2
- Molecular Weight:
- 127.14
- MDL Number:
- MFCD00055192
- MOL File:
- 64603-90-3.mol
Last updated:2023-05-04 17:34:41
| Melting point | 220 °C |
|---|---|
| Boiling point | 280.8±35.0 °C(Predicted) |
| Density | 1.199±0.06 g/cm3(Predicted) |
| RTECS | US5908286 |
| storage temp. | Store at RT |
| solubility | H2O: refrigerate if not used immediately.soluble |
| form | solid |
| pka | pK1:9.07 (25°C) |
| color | white |
| Water Solubility | Soluble in water |
| EWG's Food Scores | 1 |
| FDA UNII | YTF580771Y |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| HazardClass | IRRITANT |
ISOGUVACINE HYDROCHLORIDE price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Alfa Aesar | J63243 | Isoguvacine hydrochloride, 99% | 64603-90-3 | 100mg | $350 | 2021-12-16 | Buy |
| Tocris | 0235 | Isoguvacine hydrochloride ≥99%(HPLC) | 64603-90-3 | 100 | $223 | 2021-12-16 | Buy |
| Usbiological | 255530 | Isoguvacine hydrochloride | 64603-90-3 | 100mg | $480 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0008224 | ISOGUVACINE 95.00% | 64603-90-3 | 500MG | $718.41 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0008224 | ISOGUVACINE 95.00% | 64603-90-3 | 1G | $1021.65 | 2021-12-16 | Buy |
ISOGUVACINE HYDROCHLORIDE Chemical Properties,Uses,Production
Description
This base is isolated, together with Guvacine (q.v.) from the nuts of Areca catechu. It is optically inactive and yields crystalline salts: the hydrochloride, m.p. 231°C; aurich1oride, m.p. 198- 200°C and the p1atinich1oride, m.p. 235°C. The alkaloid is faintly acid to litmus and on methylation gives the N-methyl derivative which, on more vigorous methylation yields the dimethyl compound giving a crystalline platinichloride, m.p. 252°C. The above melting points suggest that the base may be mainly Arecaidine (q.v.) but on distillation with Zn dust, it yields products with the characteristic pyrrole reaction.
Chemical Properties
bp 195-197°C
Uses
A GABAA receptor agonist. Anticonvulsant; antiepileptic.
Definition
ChEBI: Isoguvacine is a tetrahydropyridine.
Biological Activity
Specific GABA A receptor agonist.
References
Jahns., Ber., 21,3404 (1888) Jahns., ibid, 23, 2972 (1890) Jahns., ibid, 24,2615 (1891) Jahns., Arch. Pharrn., 229, 669 (1891) Trier., Zeit. Physiol. Chern., 85,372 (1913)
ISOGUVACINE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
ISOGUVACINE HYDROCHLORIDE Suppliers
Global( 46)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23556 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 28659 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Clearsynth Labs Limited | +91-22-26355700 | info@clearsynth.com | India | 9685 | 58 |
| JW & Y Pharmlab Co., Ltd. | 021-64340559 13651849907; | xinyu_shi@jwypharmlab.com.cn | China | 12042 | 58 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
64603-90-3(ISOGUVACINE HYDROCHLORIDE)Related Search:
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ISOGUVACINE HYDROCHLORIDE
1of2
isoguvacine
C13694
1,2,3,6-tetrahydro-4-Pyridinecarboxylic acid
4-Pyridinecarboxylic acid, 1,2,3,6-tetrahydro-
ISOGUVACINE HCL
ISOGUVACINE HYDROCHLORIDE
1,2,3,6-TETRAHYDRO-PYRIDINE-4-CARBOXYLIC ACIDHYDROCHLORIDE
1,2,3,6-TETRAHYDRO-4-PYRIDINECARBOXYLIC ACID HYDROCHLORIDE
Isoguvacine hydrochl
ISOGUVACINE HYDROCHLORIDE ISO 9001：2015 REACH
64603-90-3
Cell Biology
Cell Signaling and Neuroscience
BioChemical
Ion Channels
Ligand-Gated Ion Channels
GABA and Glycine Receptor Modulators
GABA/Glycine receptor