ChemicalBook >> CAS DataBase List >>Eltanolone
Eltanolone
- CAS No.
- 128-20-1
- Chemical Name:
- Eltanolone
- Synonyms
- SKF 6455;Kabi2213;NSC 82867;Kabi 2213;Kabi-2213;ELTANOLONE;PREGNANOLONE;Pregnanolone II;EPIPREGNANOLONE;3α,5β-Pregnanolone
- CBNumber:
- CB7407837
- Molecular Formula:
- C21H34O2
- Molecular Weight:
- 318.49
- MDL Number:
- MFCD00067137
- MOL File:
- 128-20-1.mol
- MSDS File:
- SDS
Last updated:2023-06-30 15:45:59
| Melting point | 149°C |
|---|---|
| alpha | D23 +59.6° (c = 0.3 in chloroform); D26 +108.5 ±1° (c = 9.23 mg/1.23 ml abs ethanol) |
| Boiling point | 397.64°C (rough estimate) |
| Density | 1.0234 (rough estimate) |
| refractive index | 1.5344 (estimate) |
| storage temp. | Store at RT |
| solubility | Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly) |
| pka | 15.12±0.70(Predicted) |
| form | Solid |
| color | White to Off-White |
| Water Solubility | 8mg/L(room temperature) |
| FDA UNII | BXO86P3XXW |
| NIST Chemistry Reference | 3Alpha-hydroxy-5beta-pregnan-20-one(128-20-1) |
Eltanolone price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | P8129 | 5β-Pregnan-3α-ol-20-one | 128-20-1 | 25mg | $313 | 2024-03-01 | Buy |
| TRC | P711300 | 5β-Pregnan-3α-ol-20-one | 128-20-1 | 25mg | $430 | 2021-12-16 | Buy |
| TRC | P711300 | 5β-Pregnan-3α-ol-20-one | 128-20-1 | 10mg | $185 | 2021-12-16 | Buy |
| ApexBio Technology | B7455 | 1-((3R,5R,8R,9S,10S,13S,14S,17S)-3-hydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethanone | 128-20-1 | 50mg | $223 | 2021-12-16 | Buy |
| IsoSciences | 13398 | Pregnanolone ≥98% | 128-20-1 | 1mg | $239 | 2021-12-16 | Buy |
Eltanolone Chemical Properties,Uses,Production
Uses
A hyponotic-anaesthetic agent.
Definition
ChEBI: The 3alpha-stereoisomer of 3-hydroxy-5beta-pregnan-20-one.
Biological Activity
GABA A receptor positive allosteric modulator. Neuroactive steroid.
Biochem/physiol Actions
5β-Pregnan-3α-ol-20-one or pregnanolone is a neurosteroid that acts as a positive allosteric modulator (PAMs) of γ-aminobutyric acid A receptors (GABAARs). It mediates anti-convulsive, anxiolytic and sedative effects. Pregnanolone inhibits γ-aminobutyric acid C receptor (GABAC) receptor-based response and favors GABAA?receptor-mediated currents.
storage
Store at RT
Eltanolone Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 86)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 50000 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32344 | 50 |
3alpha,5beta-Epimeric pregnanolone
3alpha,5beta-Pregnanolone
3-alpha-hydroxy-5-beta-pregnan-20-on
Pregnan-20-one, 3-hydroxy-, (3a,5b)-
Pregnan-3α-ol-20-one
3a,5b-Epimeric pregnanolone
1-[(3R,5R,8R,9S,10S,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone
5B-Pregnan-3α-ol-20-one
(3α,5β)-3-Hydroxy-pregnan-20-one
3-Deoxo-3α-hydroxy-5β-dihydroprogesterone
3α,5β-Pregnanolone
3α-Hydroxy-20-oxo-5β-pregnane
3α-Hydroxy-5β-tetrahydroprogesterone
NSC 82867
5beta-Pregnan-20-one, 3alpha-hydroxy-
5-Pregnan-3-ol-20-one
5BETA-PREGNAN-3ALPHA-OL-20-ONE
5B-PREGNAN-3A-OL-20-ONE
3ALPHA-HYDROXY-5BETA-PREGNAN-20-ONE
3ALPHA-HYDROXY-5BETA-TETRAHYDRO-PROGESTERONE
3A-HYDROXY-5B-PREGNAN-20-ONE
3a,5b-epimeric pregnanolone
PREGNANOLONE
PREGNAN-3A-OL-20-ONE
pregnan-3a-ol-20-one
Pregnan-20-one, 3-hydroxy-, (3alpha,5beta)-
Pregnan-3alpha-ol-20-one
Pregnanolone II
SKF 6455
EPIPREGNANOLONE
ELTANOLONE
5A-PREGNAN-3SS-OL-20-ONE
5A-PREGNAN-3B-OL-20-ONE ENTERPRISE STANDARD,98+%
5A-PREGNAN-3A-OL-20-ONE
3α-Hydroxy-5β-pregnan-20-one, 3α-Hydroxy-5β-tetrahydroprogesterone, Pregnanolone
3a,5b-Tetrahydroprogesterone
3a-Hydroxy-5b-tetrahydroprogesterone
Pregnanolone (Solution)
5β-Pregnan-3α-ol-20-one
5beta-Pregnan-3a-ol-20-one
5-β-Pregnan-3a-ol-20-one
Kabi 2213
Kabi2213
Kabi-2213
Pregnan-20-one, 3-hydroxy-, (3α,5β)-
128-20-1
Steroids
Pharmaceutical Intermediates