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Oxolinic acid

Description References
Oxolinic acid
Oxolinic acid
CAS No.
14698-29-4
Chemical Name:
Oxolinic acid
Synonyms
w4565;ossian;oxoboi;pietil;s-0208;uroxol;utibid;starner;ultibid;nidantin
CBNumber:
CB8177186
Molecular Formula:
C13H11NO5
Formula Weight:
261.23
MOL File:
14698-29-4.mol

Oxolinic acid Properties

Melting point:
314-316°C (dec.)
Boiling point:
473℃
Flash point:
>110°(230°F)
storage temp. 
2-8°C
solubility 
Soluble in 0.5N NaOH with warming
form 
Crystalline Powder
color 
White
Sensitive 
Light Sensitive
Merck 
13,7014
Stability:
Stable. Combustible.
CAS DataBase Reference
14698-29-4(CAS DataBase Reference)
EPA Substance Registry System
1,3-Dioxolo[4,5- g]quinoline-7-carboxylic acid, 5-ethyl-5,8-dihydro-8-oxo- (14698-29-4)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xn
Risk Statements  22
Safety Statements  22-24/25-60-36
WGK Germany  3
RTECS  JI5075000
10
Hazardous Substances Data 14698-29-4(Hazardous Substances Data)
Symbol(GHS):
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P330 Rinse mouth.

Oxolinic acid price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 67126 Oxolinic acid analytical standard 14698-29-4 100mg $50.6 2017-11-08 Buy
Sigma-Aldrich O0240000 Oxolinic acid European Pharmacopoeia (EP) Reference Standard 14698-29-4 1EA $168 2017-11-08 Buy
Alfa Aesar J66637 Oxolinic acid, 98% 14698-29-4 25g $363 2017-11-08 Buy
Alfa Aesar J66637 Oxolinic acid, 98% 14698-29-4 5g $108 2017-11-08 Buy
Cayman Chemical 16789 Oxolinic Acid ≥98% 14698-29-4 5g $63 2017-11-08 Buy

Oxolinic acid Chemical Properties,Uses,Production

Description

Developed in Japan in the 1970s, oxolinic acid belongs to the family of quinolone antibiotic, which is a synthetic antimicrobial agent aiming at gram-negative bacteria, especially those responsible for urinary tract infections. It is also commonly used in clinical for microbiological antimicrobial susceptibility tests against gram negative microbial isolates, providing antibiotic treatment options for infected patients. It can serve as a selective agent in several types of isolation media, for example, to isolate Gardnerella vaginalis. Besides, oxolinic acid can be applied in agriculture, which has proved to be effective against the seed-borne pathogen, such as Burkholderia glumae, a bacteria inducing grain rot, sheath rot, seedling rot, and bacterial panicle blight.
Oxolinic acid works by targeting DNA gyrase or topoisomerase II, enzymes vital for DNA synthesis, which ultimately inhibits DNA synthesis and cell division.

References

https://en.wikipedia.org/wiki/Oxolinic_acid
http://www.toku-e.com/product/oxolinic_acid/
https://www.goldbio.com/product/3027/oxolinic-acid

Chemical Properties

Crystalline Solid

Uses

Oxolinic acid is a quinolone antibiotic used for studies on DNA winding and coiling and for studies on dopaminergic neurotransmission processes. It is used to study new transmissible resistance mechanisms qnrA, qnrB, qnrS, and aac(6′)Ib-cr, in Escherichia

Uses

Quinolone antibacterial.

Definition

ChEBI: A quinolinemonocarboxylic acid having the carboxy group at position 7 as well as oxo and ethyl groups at positions 4 and 1 respectively and a dioxolo ring fused at the 5- and 6-positions. A synthetic antibiotic, it is used in veterinary medicine for the tr atment of bacterial infections in cattle, pigs and poultry.

Oxolinic acid Preparation Products And Raw materials

Raw materials

Preparation Products


Oxolinic acid Suppliers

Global( 154)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20811 55
Mainchem Co., Ltd.
0592-6210733
0592-6210733 sales@mainchem.com CHINA 3168 55
Hubei Bangsun Chemical Co., Ltd. 18171081685
027-83219882 2834045742@qq.com China 337 58
Wuhan Dahua Weiye Pharmaceutical Chemical Co., Ltd. 027-59262863 13277907145 QQ 3091977954
027-83322098 dh.luna@whdhwy.com China 1973 50
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96820 76
Meryer (Shanghai) Chemical Technology Co., Ltd. +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-62670440(Beijing)
+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing) sh@meryer.com China 40398 62
Chemfun Medical Technology(Shanghai) Co., Ltd. 021-67220633 & 021-37212706
+86-21-67220638 chemfun@chemfun.net China 21899 59
Chemsky(shanghai)International Co.,Ltd. 021-50135380
shchemsky@sina.com China 32527 50
XiaoGan ShenYuan ChemPharm co,ltd Tell:86-712-2580635 Mobile:15527768850 . 15527768836
86-712-2580625 QQ:1623551145 sales02@farchem.com China 9170 52
SHANGHAI HOHANCE CHEMICAL CO.,LTD 0086 021 31115312
0086 021 31115317 info@hohance.com China 234 62

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