ChemicalBook
Chinese Japanese Germany

Fludarabine

Fludarabine
Fludarabine
CAS No.
21679-14-1
Chemical Name:
Fludarabine
Synonyms
f-ara-a;Fludara;2-F-ARAA;NSC 118218;NSC-312887;NSC-328002;ludarabine;21697-14-1;FLUDARUBINE;FLUDARABINE
CBNumber:
CB8188247
Molecular Formula:
C10H12FN5O4
Formula Weight:
285.23
MOL File:
21679-14-1.mol

Fludarabine Properties

Melting point:
265-268°C
alpha 
D25 +17 ±2.5° (c = 0.1 in ethanol)
storage temp. 
2-8°C
solubility 
DMF: 20 mg/mL, clear, faintly yellow
form 
Powder
color 
White to Pale Yellow
Water Solubility 
Soluble in DMF, DMSO, methanol or ethanol. Sparingly soluble in water
Merck 
13,4152
CAS DataBase Reference
21679-14-1(CAS DataBase Reference)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xn
Risk Statements  23/24/25-36/37/38-39/23/24/25-39-22
Safety Statements  26-36/37-45-36
WGK Germany  3
RTECS  AU6207000
10
Hazardous Substances Data 21679-14-1(Hazardous Substances Data)
Symbol(GHS):
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
Precautionary statements:

Fludarabine price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich F2773 2-Fluoroadenine-9-β-D-arabinofuranoside DNA synthesis and methylation inhibitor 21679-14-1 5mg $117.5 2017-11-08 Buy
Sigma-Aldrich F2773 2-Fluoroadenine-9-β-D-arabinofuranoside DNA synthesis and methylation inhibitor 21679-14-1 10mg $212 2017-11-08 Buy
Alfa Aesar J65562 2-Fluoro-9-beta-D-arabinofuranosyladenine, 98% 21679-14-1 1g $68.5 2017-11-08 Buy
Cayman Chemical 14128 Fludarabine ≥98% 21679-14-1 5mg $25 2017-11-08 Buy
Cayman Chemical 14128 Fludarabine ≥98% 21679-14-1 10mg $43 2017-11-08 Buy

Fludarabine Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

Used as an antineoplastic

Uses

A STAT-1 activation inhibitor and a DNA synthesis inhibitor.?

Uses

phosphate as antineoplastic;inhibits DNA synthesis by interfering with ribonucleotide reductase and DNA polymerase

Uses

Irreversible muscarinic agonist

Uses

DNA synthesis and methylation inhibitor;A cell permeable agent that interferes with DNA synthesis and repair; also inhibits RNA transcription

Biological Activity

Purine analog that inhibits DNA synthesis. Exhibits antiproliferative activity (IC 50 = 1.54 μ M in RPMI cells) and triggers apoptosis through increasing Bax and decreasing Bid, XIAP and survivin expression. Displays anticancer activity against hematological malignancies in vivo .

Fludarabine Preparation Products And Raw materials

Raw materials

Preparation Products


Fludarabine Suppliers

Global( 259)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3230 55
Shanghai YuLue Chemical Co., Ltd. 021-13671753212 13917602471 021-60345187
021-34702061 lzz841106@aliyun.com China 9995 55
Hongene Biotechnology Limited 86-21-64757213
86-21-64700613 info@hongene.com; sales@hongene.com China 437 61
Wuhu Nuowei chemistry Co., Ltd. 0553-2911116 18055311600
0553-2911116 salesnuowei@163.com China 1104 55
Target molecule Corp. 857-239-0968
857-239-8801 market@targetmol.com United States 2567 60
ShangHai Wisacheam Pharmaceutical Co., Ltd. 13817485796 13122608669 QQ:895624079
021-20422036 tim@wisacheampharm.com China 3800 58
Fujian South Pharmaceutical Co., Ltd. +86-598-2817680 13358505380
+86-598-2860416 sales@southpharma.com China 64 55
Nanjing Xinmeihe Pharmaceutical Co., Ltd. 025-66073376 13739186949
025-66073376 2548785915@qq.com China 47 58
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96831 76
3B Pharmachem (Wuhan) International Co.,Ltd. 86-21-50328103 * 801、802、803、804 Mobile:18930552037
86-21-50328109 3bsc@sina.com China 15950 69

21679-14-1(Fludarabine)Related Search:


Copyright 2017 © ChemicalBook. All rights reserved