EC 2.4.2.4

CAS No.
9030-23-3
Chemical Name:
EC 2.4.2.4
Synonyms
TYMP;MNGIE;ECGF1;Gliostatin;EC 2.4.2.4;THYMIDINE PHOSPHORYLASE;Phosphorylase,thymidine;Thymidine Phosphorylase, recombinant;THYMIDINE PHOSPHORYLASE FROM*ESCHERICHIA COLI;ANTI-ECGF1 (CENTER) antibody produced in rabbit
CBNumber:
CB8341855
Molecular Formula:
Molecular Weight:
0
MDL Number:
MFCD00132426
MOL File:
Mol file
Last updated:2023-04-23 13:52:06

EC 2.4.2.4 Properties

storage temp. 2-8°C
form buffered aqueous solution

SAFETY

Risk and Safety Statements

WGK Germany  -

EC 2.4.2.4 price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T2807 Thymidine Phosphorylase, recombinant from Escherichia coli recombinant, expressed in E. coli, buffered aqueous solution, ≥500?units/mL 9030-23-3 500units $156 2024-03-01 Buy
Sigma-Aldrich T2807 Thymidine Phosphorylase, recombinant from Escherichia coli recombinant, expressed in E. coli, buffered aqueous solution, ≥500?units/mL 9030-23-3 1000units $201 2024-03-01 Buy
Sigma-Aldrich T6632 Thymidine Phosphorylase, recombinant from Escherichia coli recombinant, expressed in E. coli, buffered aqueous solution, ≥900?units/mL, aseptically filled 9030-23-3 5000units $1600 2024-03-01 Buy
Sigma-Aldrich T2807 Thymidine Phosphorylase, recombinant from Escherichia coli recombinant, expressed in E. coli, buffered aqueous solution, ≥500?units/mL 9030-23-3 5000units $411.6 2024-03-01 Buy
Sigma-Aldrich SRE0006 Thymidine Phosphorylase, recombinant from Escherichia coli recombinant, expressed in E. coli, Suitable for manufacturing of diagnostic kits and reagents, buffered aqueous solution, ≥500?units/mL 9030-23-3 5000units $300 2024-03-01 Buy
Product number Packaging Price Buy
T2807 500units $156 Buy
T2807 1000units $201 Buy
T6632 5000units $1600 Buy
T2807 5000units $411.6 Buy
SRE0006 5000units $300 Buy

EC 2.4.2.4 Chemical Properties,Uses,Production

Uses

Thymidine phosphorylase has been used in a study to assess TAS-102 treatment in patients with advanced solid tumors. Thymidine phosphorylase has also been used in a study to investigate antitumor effects of the FP3 protein on patient-derived tumor tissue xenograft models of primary colon carcinoma.

Uses

Thymidine phosphorylase has been used in a study to evaluate biomarkers for advanced breast cancer patients treated with capecitabine-based first-line chemotherapy. Thymidine phosphorylase has also been used in a study to investigate implications for the clinical efficacy of nucleoside analogues.

General Description

Thymidine phosphorylase inhibits vascular smooth muscle cell proliferation.

Biochem/physiol Actions

An enzyme that catalyzes the reversible conversion of thymidine to thymine. Thymidine phosphorylase is part of the pyrimidine nucleoside salvage pathway. This pathway allows pyrimidine bases to be recycled for nucleotide biosynthesis, while the pentose 1-phosphates are converted to intermediates of the pentose phosphate shunt and glycolysis. The E. coli thymidine phosphorylase shares 40% sequence homology with the human sequence, which has been found to be identical to the angiogenic agent platelet-derived endothelial growth factor. The purified E. coli enzyme has been shown to stimulate blood vessel growth in chick chorioallantoic membrane assays.

EC 2.4.2.4 Preparation Products And Raw materials

Raw materials

Preparation Products

EC 2.4.2.4 Suppliers

Global( 11)Suppliers
Supplier Tel Email Country ProdList Advantage
Creative Enzymes
1-516-855-7709 info@creative-enzymes.com United States 8748 58
Shanghai Acmec Biochemical Technology Co., Ltd.
+undefined18621343501 product@acmec-e.com China 33350 58
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Guangzhou Tomums Life Science Co., Ltd. 020-31155029 18902330969 sales@tomums.cn China 4698 58
Shanghai Huzhen Industrial Co., LTD 021-60345367 13916550749 sales@shzbio.com China 9965 58
Shanghai Guchen Biotechnology Co., LTD 021-34675735 19147740836 1986399151@qq.com China 9849 58
EC 2.4.2.4 THYMIDINE PHOSPHORYLASE FROM*ESCHERICHIA COLI THYMIDINE PHOSPHORYLASE, RECOMBINANT*FRO M E. COLI THYMIDINE PHOSPHORYLASE, ASEPTICALLY*FIL LED, FROM E thymidine:orthophosphate deoxy-d-ribosyltransferase Thymidine Phosphorylase, recombinant from Escherichia coli MNGIE ANTI-ECGF1 (CENTER) antibody produced in rabbit ECGF1 Gliostatin TYMP THYMIDINE: ORTHOPHOSPHATE DEOXYRIBOSYLTRANSFERASE THYMIDINE PHOSPHORYLASE Thymidine Phosphorylase, recombinant Thymidine Phosphorylase from Escherichia coli, Recombinant Phosphorylase,thymidine Thymidine Phosphorylase, recombinant from Escherichia coli recombinant, expressed in E. coli, buffered aqueous solution, >=900 units/mL, aseptically filled Thymidine Phosphorylase, recombinant from Escherichia coli recombinant, expressed in E. coli, Suitable for manufacturing of diagnostic kits and reagents, buffered aqueous solution, >=500 units/mL Thymidine Phosphorylase, recombinant from Escherichia coli recombinant, expressed in E. coli, buffered aqueous solution, >=500 units/mL 9030-23-3 Application Index BioChemical Biochemicals and Reagents Metabolomics Nucleotide Metabolism General Metabolic Enzymes Diagnostic and Analytical Enzymes Enzymes, Inhibitors, and Substrates