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4ALPHA-PHORBOL 12,13-DIDECANOATE

CAS No.
27536-56-7
Chemical Name:
4ALPHA-PHORBOL 12,13-DIDECANOATE
Synonyms
4a-PDD;4ALPHA-PDD;4α-Phorbol 12;13-didecanoate;4alphaPDD,4alpha PDD;-Phorbol12,13-didecanoate;4α-phorbol 12-13-dicaprinate;4a-Phorbol-12,13-didecanoate;4α-Phorbol 12,13-didecanoate;4alpha-Phorbol 12,13-dideconate
CBNumber:
CB9171479
Molecular Formula:
C40H64O8
Molecular Weight:
672.93
MDL Number:
MFCD00036737
MOL File:
27536-56-7.mol
MSDS File:
SDS
Last updated:2023-06-08 09:02:47

4ALPHA-PHORBOL 12,13-DIDECANOATE Properties

storage temp. -20°C
solubility DMSO: soluble
form solid
color white
BRN 2514324

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS05,GHS06,GHS08
Signal word  Danger
Hazard statements  H300+H310+H330-H314-H317-H334-H351
Precautionary statements  P201-P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338
Hazard Codes  T+
Risk Statements  26/27/28-40-43
Safety Statements  36/37/39-45
RIDADR  UN 2811 6.1/PG 2
WGK Germany  3
8-10
HazardClass  6.1(b)
PackingGroup  III
NFPA 704
0
4 0

4ALPHA-PHORBOL 12,13-DIDECANOATE price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 524394 4α-Phorbol-12,13-didecanoate 27536-56-7 1mg $125 2024-03-01 Buy
Sigma-Aldrich 524394 4α-Phorbol-12,13-didecanoate 27536-56-7 5mg $476 2024-03-01 Buy
Cayman Chemical 20446 4α-Phorbol 12,13-didecanoate ≥99% 27536-56-7 1mg $100 2024-03-01 Buy
Cayman Chemical 20446 4α-Phorbol 12,13-didecanoate ≥99% 27536-56-7 5mg $425 2024-03-01 Buy
Sigma-Aldrich P8014 4α-Phorbol 12,13-didecanoate solid 27536-56-7 1mg $204 2024-03-01 Buy
Product number Packaging Price Buy
524394 1mg $125 Buy
524394 5mg $476 Buy
20446 1mg $100 Buy
20446 5mg $425 Buy
P8014 1mg $204 Buy

4ALPHA-PHORBOL 12,13-DIDECANOATE Chemical Properties,Uses,Production

Uses

4α-Phorbol 12,13-didecanoate has been used as a transient receptor potential vanilloid 4 (TRPV4) agonist:

  • to study its effects on Madin-Darby canine kidney (MDCK) cells
  • to study its effects on Ca2+ influx in mice fallopian tubal cells
  • to study its effects on hind paw swelling in mice

Definition

ChEBI: 4alpha-phorbol 12,13-didecanoate is a phorbol ester that is phorbol in which the hydroxy groups at the cyclopropane ring juction (position 13) and the adjacent carbon (position 12) have been converted to the corresponding decanoate esters. A Trpv4-specific ligand. It has a role as a TRPV4 agonist. It is a phorbol ester, a decanoate ester, a tertiary alpha-hydroxy ketone, a diester and a primary allylic alcohol.

Biochem/physiol Actions

4α-Phorbol 12,13-didecanoate is a transient receptor potential vanilloid 4 (TRPV4) agonist. It promotes extracellular calcium influx into the cells.

4ALPHA-PHORBOL 12,13-DIDECANOATE Preparation Products And Raw materials

Raw materials

Preparation Products

4ALPHA-PHORBOL 12,13-DIDECANOATE Suppliers

Global( 38)Suppliers
Supplier Tel Email Country ProdList Advantage
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49390 58
TargetMol Chemicals Inc.
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Hangzhou MolCore BioPharmatech Co.,Ltd.
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Shanghai Acmec Biochemical Technology Co., Ltd.
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J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9709 58
Jinan Yaoyan Pharmaceutical Co., Ltd. jnyaoyan@163.com China 3069 58
Nanjing Meihao Pharmaceutical Technology Co., Ltd. meitaochem@126.com meitaochem@126.com China 19105 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
4ALPHA-PDD 4ALPHA-PHORBOL 12-13-DICAPRINATE 4ALPHA-PHORBOL 12,13-DIDECANOATE 4a-Phorbol-12,13-didecanoate 4A-PHORBOL 12,13-DIDECANOATE WEAK PROTEI N KINASE C 4α-phorbol 12-13-dicaprinate 4A-PHORBOL 12,13-DIDECANOATE, 99+% phorbol (4alpha-) 12,13-didecanoate 4α-Phorbol 12-13-dicaprinate, 4αPDD 4alpha-Phorbol 12,13-dideconate Decanoic acid, 1,1A,1B,4,4A,5,7A,7B,8,9-decahydro-4A,7B-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-9ah-cyclopropa(3,4)benz(1,2-E)azulene-9,9A-diyl ester, (1ar-(1aalpha,1bbeta,4aalpha,7aalpha,7balpha,8alpha,9beta,9aalpha))- 4-alpha-Phorbol 12,13-Didecanoate >99% 4α-Phorbol 12,13-Didecanoate, >99% 4a-PDD 4α-Phorbol-12,13-didecanoate - CAS 27536-56-7 - Calbiochem Decanoic acid, 1,1'-[(1aR,1bS,4aS,7aS,7bS,8R,9R,9aS)-1,1a,1b,4,4a,5,7a,7b,8,9-decahydro-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-9aH-cyclopropa[3,4]benz[1,2-e]azulene-9,9a-diyl] ester 4α-Phorbol 12,13-didecanoate -Phorbol12,13-didecanoate 13-didecanoate 4α-Phorbol 12 4alphaPDD,4alpha PDD 4alpha-Phorbol 12,13-didecanoate solid 27536-56-7 C40H64O8 Kinase/Phosphatase Biology Serine/Threonine Kinase Activators Protein Kinase C (PKC) Cell Signaling and Neuroscience Cell Biology BioChemical metabolite