3-Methylamino-1,2-propanediol
- CAS No.
- 40137-22-2
- Chemical Name:
- 3-Methylamino-1,2-propanediol
- Synonyms
- 3-Methylamino-1,2-Propandiol;3-METHYLAMINO-1,2-PROPANEDIOL;3-METHYLAMINO-PROPANE-1,2-DIOL;3-(methylamino)propane-1,2-dio;3-(AMINOMETHYL)-1,2-PROPANEDIOL;N-METHYL-3-AMINO-1,2-PROPANEDIOL;3-Methylamino-1,2-propanediol>1,2-Propanediol, 3-(methylamino)-;N-Methyl-2,3-dihydroxypropylamine;2,3-Dihydroxy-N-methylpropylamine
- CBNumber:
- CB9174021
- Molecular Formula:
- C4H11NO2
- Molecular Weight:
- 105.14
- MDL Number:
- MFCD00082732
- MOL File:
- 40137-22-2.mol
| Melting point | 69°C (estimate) |
|---|---|
| Boiling point | 247 °C |
| Density | 1.095 g/mL at 20 °C(lit.) |
| refractive index |
n |
| Flash point | 152 °C |
| storage temp. | Inert atmosphere,Room Temperature |
| pka | 14.09±0.20(Predicted) |
| form | clear liquid |
| color | Colorless to Almost colorless |
| Specific Gravity | 1.0921 |
| PH | 11.5 (100g/l, H2O, 20℃) |
| Water Solubility | miscible |
| BRN | 1733341 |
| CAS DataBase Reference | 40137-22-2(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335-H314-H318 | |||||||||
| Precautionary statements | P261-P305+P351+P338-P260h-P301+P330+P331-P303+P361+P353-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36-37/39 | |||||||||
| RIDADR | 2735 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 3-10-34 | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29221980 | |||||||||
| Toxicity | LD50 orally in Rabbit: > 2000 mg/kg | |||||||||
| NFPA 704 |
|
3-Methylamino-1,2-propanediol price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | M1243 | 3-Methylamino-1,2-propanediol >98.0%(GC)(T) | 40137-22-2 | 25g | $57 | 2024-03-01 | Buy |
| Alfa Aesar | L12653 | 3-Methylamino-1,2-propanediol, 99% | 40137-22-2 | 25g | $39.65 | 2024-03-01 | Buy |
| Alfa Aesar | L12653 | 3-Methylamino-1,2-propanediol, 99% | 40137-22-2 | 100g | $115.65 | 2024-03-01 | Buy |
| TRC | M332493 | 3-Methylamino-1,2-propanediol | 40137-22-2 | 5g | $60 | 2021-12-16 | Buy |
| Matrix Scientific | 091200 | 3-(Methylamino)propane-1,2-diol 98% | 40137-22-2 | 5g | $61 | 2021-12-16 | Buy |
3-Methylamino-1,2-propanediol Chemical Properties,Uses,Production
Description
3-Methylamino-1,2-propanediol (MAPD) is a clear liquid with the chemical formula C4H11NO2. It can be synthesized from allylamine and alkanolamine via a thermal process. It reacts with chloride to form methyl chloroacetate, which can then be converted into 3-methylamino-1,2-propanediol by reaction with methanol. The production process for this substance has been shown to generate low levels of hazardous substances such as polycyclic aromatic hydrocarbons (PAHs) and dioxins.
Chemical Properties
clear colorless to pale yellow viscous liquid
Uses
3-Methylamino-1,2-propanediol is a reactive compound that is used in the synthesis of organic acids. It is also used as an intermediate in the manufacture of polyethylene glycols and particle coatings.
Definition
ChEBI: 3-methylamino-1,2-propanediol is a secondary amine.
Preparation
3-Methylamino-1,2-propanediol (MAPD) is synthesized by reacting 3-chloro-1,2-propanediol (CPD) with
monomethyl amine in alkaline environment by adding sodium hydroxide.
Afterwards, the product undergoes a series of purification steps. 
N-Methyl-1-amino-2,3-propandiol (45A) Methylamine (172ml of a 40% solution in water, 2 mol) was cooled to 0 °C and 2,3-epoxy-1-propanol (25g, 0.34mol) was added at a rate to maintain the temperature at or below 10 °C. The mixture was stirred for 3 hours at 0 °C. Excess methylamine and water was evaporated in vacuo and the product was purified by distillation at 103-105 °C, at 0.5 mm Hg, to give the compound 3-Methylamino-1,2-propanediol.
Hazard
3-Methylamino-1,2-propanediol is danger.
H314 (32.76%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]
H315 (67.24%): Causes skin irritation [Warning Skin corrosion/irritation]
H319 (65.52%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
3-Methylamino-1,2-propanediol Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Guanlang Biotechnology Co,.LTD | +8619930503252 | daisy@crovellbio.com | China | 5964 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 8095 | 58 |
| Ouhuang Engineering Materials (Hubei) Co., Ltd | +8617702722807 | admin@hbouhuang.com | China | 2880 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21691 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
View Lastest Price from 3-Methylamino-1,2-propanediol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-23 | 3-Methylamino-1,2-propanediol
40137-22-2
|
US $10.00 / kg | 1kg | 99.6% | 100000 | Ouhuang Engineering Materials (Hubei) Co., Ltd | |
 |
2024-03-23 | 3-Methylamino-1,2-propanediol
40137-22-2
|
US $32.00-1.50 / kg | 1kg | 99% | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | |
 |
2023-08-24 | 3-Methylamino-1,2-propanediol
40137-22-2
|
US $10.00 / KG | 1KG | 99.% | 10 ton | Hebei Guanlang Biotechnology Co,.LTD |
-
- 3-Methylamino-1,2-propanediol
40137-22-2
- US $10.00 / kg
- 99.6%
- Ouhuang Engineering Materials (Hubei) Co., Ltd
-
- 3-Methylamino-1,2-propanediol
40137-22-2
- US $32.00-1.50 / kg
- 99%
- Henan Fengda Chemical Co., Ltd
-
- 3-Methylamino-1,2-propanediol
40137-22-2
- US $10.00 / KG
- 99.%
- Hebei Guanlang Biotechnology Co,.LTD