ChemicalBook
Chinese Japanese Germany

Methylamine

Organic Chemicals Poisoning Uses Production method
Methylamine
Methylamine
CAS No.
74-89-5
Chemical Name:
Methylamine
Synonyms
CH3NH2;MMA-40;MMA-50;AMINE C1;Methylamin;Metilamine;Methanamine;Carbinamine;Aminomethan;Metyloamina
CBNumber:
CB4387750
Molecular Formula:
CH5N
Formula Weight:
31.06
MOL File:
74-89-5.mol

Methylamine Properties

Melting point:
-93 °C(lit.)
Boiling point:
-6.3 °C(lit.)
Density 
0.785 g/mL at 25 °C
vapor density 
1.08 (20 °C, vs air)
vapor pressure 
27 psi ( 20 °C)
refractive index 
n20/D 1.371
Flash point:
61 °F
storage temp. 
Flammables area
pka
10.63(at 25℃)
explosive limit
4.9-20.8%
Water Solubility 
Miscible with water, ethanol, benzene, acetone and ether.
Merck 
14,6014
BRN 
741851
Stability:
Stable. Highly flammable. Note wide explosion limits. Incompatible with oxidizing agents, acids, alkalies, alkaline earth metals, copper and its alloys, zinc and its alloys.
CAS DataBase Reference
74-89-5(CAS DataBase Reference)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  F+,Xn,C,F,T
Risk Statements  12-20-37/38-41-34-20/22-11-39/23/24/25-36/37/38-23/24/25-40-19
Safety Statements  7-16-26-36/37-45-29-36/37/39-3/7-3-39-33
RIDADR  UN 3286 3/PG 2
WGK Germany  2
RTECS  PF6300000
4.5-31
TSCA  Yes
HazardClass  3
PackingGroup  II
Symbol(GHS):
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H220 Extremely flammable gas Flammable gases Category 1 Danger P210, P377, P381, P403
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H280 Contains gas under pressure; may explode if heated Gases under pressure Compressed gas
Liquefied gas
Dissolved gas
Warning P410+P403
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger P264, P270, P301+P310, P321, P330,P405, P501
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H311 Toxic in contact with skin Acute toxicity,dermal Category 3 Danger P280, P302+P352, P312, P322, P361,P363, P405, P501
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger P280, P305+P351+P338, P310
H331 Toxic if inhaled Acute toxicity,inhalation Category 3 Danger P261, P271, P304+P340, P311, P321,P403+P233, P405, P501
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning P261, P271, P304+P340, P312
H333 May be harmful if inhaled Acute toxicity,inhalation Category 5 P304+P312
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
H370 Causes damage to organs Specific target organ toxicity, single exposure Category 1 Danger P260, P264, P270, P307+P311, P321,P405, P501
Precautionary statements:
P201 Obtain special instructions before use.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P310 Immediately call a POISON CENTER or doctor/physician.
P377 Leaking gas fire: Do not extinguish, unless leak can be stopped safely.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P370+P378 In case of fire: Use … for extinction.
P405 Store locked up.
P403+P235 Store in a well-ventilated place. Keep cool.
P410+P403 Protect from sunlight. Store in a well-ventilated place.

Methylamine price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 395048 Methylamine solution 2.0M in methanol 74-89-5 100ml $118.5 2017-11-08 Buy
Sigma-Aldrich 295531 Methylamine anhydrous, ≥98% 74-89-5 170g $498.5 2017-11-08 Buy
TCI Chemical M0137 Methylamine (ca. 40% in Water, ca. 12mol/L) 74-89-5 25mL $14 2017-12-01 Buy
TCI Chemical M0137 Methylamine (ca. 40% in Water, ca. 12mol/L) 74-89-5 500mL $16 2017-12-01 Buy
Alfa Aesar H26889 Methylamine, 2M in methanol 74-89-5 100ml $92.7 2017-11-08 Buy

Methylamine Chemical Properties,Uses,Production

Organic Chemicals

Methylamine, also known as amino methane, is an important kind of organic chemical raw materials and intermediates and is a flammable colorless gas at normal temperature and pressure. Upon being liquefied or compressed at high concentrations, it has a strong odor of ammonia. It has fishy odor at very low concentrations. It is easily soluble in water and soluble in alcohol and ether. It is flammable and can form explosive mixtures with air with the explosive limit being 4.3% to 21%. It has weak alkalinity with the alkaline being stronger than ammonia. It can interact with inorganic acid to form water-soluble salts. It is obtained through the reaction between methanol and ammonia at high pressure and high temperature in the action of catalyst. Alternatively, it can be obtained through the reaction between formaldehyde and ammonium chloride upon being heated to 300 ℃ in the presence of zinc chloride. Methylamine can be used to make pesticides, pharmaceuticals, rubber vulcanization accelerator, dyes, explosives, leather, petroleum, surfactants, and ion exchange resin, paint strippers, and coatings as well as additives. It is an important raw material for the manufacturing of pesticide dimethoate, carbaryl, and chlordimeform. The inhalation toxicity of methylamine belongs to low toxicity category. The maximum allowable air concentration is 5mg/m3 (0.4ppm). It is corrosive and can cause irritation of the eyes, skin and mucous membranes. In case of fire, high heating temperature, it can cause risk of fire with cylinders and accessories damage being capable of causing an explosion.

Poisoning

Methylamine belongs to moderate-poisoning drug with a strong irritant and corrosive property. During the process of production and in transit, when there is leakage occurring due to accident, it can cause acute poisoning of contacted people.
This product can be subject to inhalation in its gaseous state from the respiratory tract. Its solution can be absorbed through the skin. Its salt can cause poisoning upon mistakenly oral administration. This product has a strong stimulating effect on eye; upper respiratory tract, skin and mucous membranes. Inhalation of it at high concentrations can cause damage to the lungs with people in severe cases getting pulmonary edema and respiratory distress syndrome, finally leading to death. However, it has been no yet reported of cases of systemic poisoning around the world. Liquid methylamine has strong irritation and corrosion effect and can cause eye and skin chemical burning. In case of 40% aqueous methylamine being splashed into the eyes, the victims can get burning eyes, photophobia, lacrimation, conjunctival hyperemia, eyelid irritation, corneal edema and superficial ulcers with those symptoms being able to last 1 to 2 weeks. Long-term exposure to low concentrations of methylamine can cause dryness and discomfort of the eyes, nose, and throat.
[first-aid]
Upon skin contact, the victim should immediately remove the contaminated clothing, wash it thoroughly with a large amount of flowing water. For first-aid, the victim can apply 1 to 2% acetic acid, 0.5% citric acid to wash the skin, mucous membranes and mouth.
When the eyes are contaminated, they should raise the eyelid and wash the eyes with flowing clean water and saline for at least 15 minutes, followed by fluorescein staining. If there is corneal injury occurring, the victims should be invited to an ophthalmologist for treatment.
For patients inhaling nitric methylamine gas and getting poisoned, they should be rapidly transferred from the scene of fresh air and keep the airway open. For patients with breathing difficulties, they should be given oxygen. Patients of respiratory and cardiac arrest should be immediately subject to artificial respiration and sent to hospital immediately after treatment in a timely manner.
This information is edited by Xiongfeng Dai from Chemicalbook.

Uses

Methylamine is an important kind of fatty amines organic chemicals and is widely applied to pesticide production. It can be used in the synthesis of the N-methyl-chloroacetamide that is the intermediate of the organic phosphorus insecticide dimethoate and omethoate; synthesis of the intermediate of the monocrotophos, α-chloro acetoacetyl methylamine; synthesis of the intermediates of carbamate pesticide, carbamoyl chloride and methyl isocyanate; as well as the synthesis of other pesticides varieties such as formamidine, amitraz, and tribenuron, etc. In addition, it can also be used in medicine, rubber, dyes, leather industry and photosensitive materials.

Production method

There are a lot of ways for manufacturing of methylamine. But in industry, people mainly apply methanol amination.
CH3OH + NH3 → CH3NH2 + H2O
2CH3OH + NH3 → (CH3) 2NH + 2H2O
3CH3OH + NH3 → (CH3) 3N + 3H2O
It is obtained through the following process: methanol and ammonia is at a ratio of 1.5 to 4 and subject to continuous vapor phase catalytic amination at high temperature and high pressure with activated alumina as a catalyst to generate the mixture crude product of mono-, di-, trimethylamine. The crude mixture further goes through a series of distillation column for continuous pressure and distillation separation, have cooling for deamination, dehydration can yield respectively mono-, di-, trimethylamine products.

Chemical Properties

colourless gas (or solution in water or methanol)

Definition

ChEBI: The simplest of the methylamines, consisting of ammonia bearing a single methyl substituent.

General Description

A colorless gas or a liquid. Pungent fishy odor resembling odor of ammonia. The liquid boils at 20.3°F hence vaporizes rapidly when unconfined. Vapors are heavier than air and may collect in low-lying areas. Easily ignited under most conditions. Under prolonged exposure to intense heat the containers may rupture violently and rocket. Used for making pharmaceuticals, insecticides, paint removers, surfactants, rubber chemicals.

Air & Water Reactions

Highly flammable. Very soluble in water; the solutions are strongly basic and therefore corrosive. Liquid fumes in air.

Reactivity Profile

METHYLAMINE neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated in combination with strong reducing agents, such as hydrides.

Health Hazard

VAPOR: Irritating to eyes, nose and throat. If inhaled will cause coughing or difficult breathing. LIQUID: Will burn skin and eyes.

Fire Hazard

FLAMMABLE. POISONOUS GASES MAY BE PRODUCED IN FIRE. Containers may explode in fire. Flashback along vapor trail may occur. Vapor may explode if ignited in an enclosed area. Toxic nitrogen oxides may be formed. Vapors are heavier than air and may travel considerable distance to a source of ignition and flash back.

Methylamine Preparation Products And Raw materials

Raw materials

Preparation Products


Methylamine Suppliers

Global( 196)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20811 55
Mainchem Co., Ltd.
0592-6210733
0592-6210733 sales@mainchem.com CHINA 3168 55
Secco work (Beijing) chemical technology co., LTD 010-69755668;
010-69755668 1139670422@qq.com China 3546 54
Alfa Aesar 400-610-6006; 021-67582000
021-67582001/03/05 saleschina@alfa-asia.com China 30309 84
Quzhou Prince Biological Technology Co. Ltd. 0570-6581212,13567026655
0570-6259500 jeryy@cnprincebio.com China 39 58
Jonny pharmaceutical co.,ltd Ship products from Netherlands. Pls contact for PGP or ECC ID to talk!
Wickr: chemjonny, Pls contact for PGP or ECC ID to talk! chemjonny@openmailbox.org China 189 55
Energy Chemical 021-58432009 / 400-005-6266
021-58436166-800 info@energy-chemical.com China 44192 61
Shanghai Aladdin Bio-Chem Technology Co.,LTD 021-20337333/400-620-6333
021-50323701 sale@aladdin-e.com China 25121 65
Nanjing Spcscientific Technology Co., Ltd. 18994006456
sales1@spcscientific.com China 207 58
Nanjing Huang Tai Pharmaceutical Technology Co. Ltd. 18551845925QQ3569572487
025-58803650 3237333966@qq.com China 1858 58

74-89-5(Methylamine)Related Search:


Copyright 2017 © ChemicalBook. All rights reserved