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Tris Base

Chemical Properties Uses of Biology Uses

CAS No.77-86-1
Chemical Name:Tris Base
Synonyms:TRIS;THAM;Tham-E;Trizma;riladyl;thamset;TRISMAT;8VTE 1L;Pehanorm;Talatrol
CBNumber:CB8336488
Molecular Formula:C4H11NO3
Formula Weight:121.14
MOL File:77-86-1.mol
Tris Base Property
Melting point : 167-172 °C(lit.)
Boiling point : 219-220 °C10 mm Hg(lit.)
density : 1,353 g/cm3
Fp : 219-220°C/10mm
storage temp. : 2-8°C
solubility : H2O: 4 M at 20 °C, clear, colorless
form : crystalline
color : white
Water Solubility : 550 g/L (25 ºC)
Sensitive : Hygroscopic
Merck : 14,9772
BRN : 741883
Stability:: Stable. Incompatible with bases, strong oxidizing agents. Protect from moisture.
CAS DataBase Reference: 77-86-1(CAS DataBase Reference)
NIST Chemistry Reference: 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-(77-86-1)
EPA Substance Registry System: 1,3-Propanediol, 2-amino-2-(hydroxymethyl)- (77-86-1)
Safety
Hazard Codes : Xi
Risk Statements : 36/37/38
Safety Statements : 26-36-37/39-24/25-23
WGK Germany : 2
RTECS : TY2900000
F : 3
HazardClass : IRRITANT
HS Code : 29221980
Hazardous Substances Data: 77-86-1(Hazardous Substances Data)

Tris Base Chemical Properties,Usage,Production

Chemical Properties
White crystal or powder. Melting point 171-172℃, boiling point 219-220℃/1.3kPa, soluble in ethanol and water, slightly soluble in ethyl acetate, benzene, insoluble in ether, carbon tetrachloride,copper,aluminum corrosion effects,irritant.
Uses of Biology
Tris base, also known as THAM, is widely used as a biological buffer or as a component of buffer formulations such as TAE and TBE buffers. Tris has a pKa of 8.06 and is very useful in the biology and biochemistry lab because it has buffering capabilities in the range of the typical physiological pH of most living organisms (pH 7.0-9.0). Tris has been reported to interfere with the activity of a number of enzymes, it should therefore be used carefully when studying proteins.
Uses
1, Tris buffer, only nucleic acids and proteins are widely used as solvents.
2, Tris is used for protein crystal growth under different pH conditions.
3, Tris buffer having a low ionic strength can be used nematode (C. elegans) is formed lamin (lamin) intermediate fibers.
4, Tris is a major component of protein electrophoresis buffer.
5, Tris for the preparation of a surfactant, a vulcanization accelerator, and some drug intermediates.
6, Tris titrated also used as standard.
Chemical Properties
White crystalline powder
Biological Activity
Commonly used laboratory reagent
Tris Base Preparation Products And Raw materials
Raw materials
Nitromethane Potassium carbonate Paraformaldehyde Palladium Methanol Tris(hydroxymethyl)nitromethane
Preparation Products
Tris Base Suppliers      Global( 374)Suppliers     
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Spectrum Chemical Manufacturing Corp. 021-67601398-808021-57711696gduan@spectrumchina.netCHINA 9351 60
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Suzhou Yacoo Chemical Reagent Corporation 0512-81665519;0512-816677960512-87182056service2@yacoo.com.cnCHINA 1056 60
Beijing Xinsavi Chemical Technology Co., Ltd. 010-56218822010-56218800xinsavichem@163.comCHINA 4826 56
Hangzhou Dingyan Chem Co., LTD 0571-87157530,88025800,864658810571-87156470sales@dingyanchem.comCHINA 3003 58
Codow Chemical Co.,Ltd. +86-20-38056109 / 3892 1903+86-20-6261 9665sales@hwhg.com.cnCHINA 18469 55
Zhejiang Haiqiang Chemical Co.,Ltd 0571-86050367 0571-86960370 0571-860503870571-86940780info@chinahaiqiangchem.comCHINA 470 55
Hefei TNJ Chemical Industry Co.,Ltd. +86 (551) 65418684 65418696+86 (551) 65418697info@tnjchem.comCHINA 1900 62
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77-86-1(Tris Base)Related Search:
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