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Tris Base

Chemical Properties Uses of Biology Uses

CAS No.77-86-1
Chemical Name:Tris Base
Synonyms:TRIS;THAM;Tham-E;Trizma;riladyl;thamset;TRISMAT;8VTE 1L;Pehanorm;Talatrol
Molecular Formula:C4H11NO3
Formula Weight:121.14
MOL File:77-86-1.mol
Tris Base Property
Melting point : 167-172 °C(lit.)
Boiling point : 219-220 °C10 mm Hg(lit.)
density : 1,353 g/cm3
Fp : 219-220°C/10mm
storage temp. : 2-8°C
solubility : H2O: 4 M at 20 °C, clear, colorless
form : crystalline
color : white
Water Solubility : 550 g/L (25 ºC)
Sensitive : Hygroscopic
Merck : 14,9772
BRN : 741883
Stability:: Stable. Incompatible with bases, strong oxidizing agents. Protect from moisture.
CAS DataBase Reference: 77-86-1(CAS DataBase Reference)
NIST Chemistry Reference: 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-(77-86-1)
EPA Substance Registry System: 1,3-Propanediol, 2-amino-2-(hydroxymethyl)- (77-86-1)
Hazard Codes : Xi
Risk Statements : 36/37/38
Safety Statements : 26-36-37/39-24/25-23
WGK Germany : 2
RTECS : TY2900000
F : 3
TSCA : Yes
HazardClass : IRRITANT
HS Code : 29221980
Hazardous Substances Data: 77-86-1(Hazardous Substances Data)

Tris Base Chemical Properties,Usage,Production

Chemical Properties
White crystal or powder. Melting point 171-172℃, boiling point 219-220℃/1.3kPa, soluble in ethanol and water, slightly soluble in ethyl acetate, benzene, insoluble in ether, carbon tetrachloride,copper,aluminum corrosion effects,irritant.
Uses of Biology
Tris base, also known as THAM, is widely used as a biological buffer or as a component of buffer formulations such as TAE and TBE buffers. Tris has a pKa of 8.06 and is very useful in the biology and biochemistry lab because it has buffering capabilities in the range of the typical physiological pH of most living organisms (pH 7.0-9.0). Tris has been reported to interfere with the activity of a number of enzymes, it should therefore be used carefully when studying proteins.
1, Tris buffer, only nucleic acids and proteins are widely used as solvents.
2, Tris is used for protein crystal growth under different pH conditions.
3, Tris buffer having a low ionic strength can be used nematode (C. elegans) is formed lamin (lamin) intermediate fibers.
4, Tris is a major component of protein electrophoresis buffer.
5, Tris for the preparation of a surfactant, a vulcanization accelerator, and some drug intermediates.
6, Tris titrated also used as standard.
Chemical Properties
White crystalline powder
Biological Activity
Commonly used laboratory reagent
Tris Base Preparation Products And Raw materials
Raw materials
Nitromethane Potassium carbonate Paraformaldehyde Palladium Methanol Tris(hydroxymethyl)nitromethane
Preparation Products
Tris Base Suppliers      Global( 389)Suppliers     
Suzhou Yacoo Chemical Reagent Corporation 99 60
Spectrum Chemical Manufacturing Corp. 021-67601398-808021-57711696gduan@spectrumchina.netChina 9334 60
Beijing Xinsavi Chemical Technology Co., Ltd. 13717722232010-56218800xinsavichem@163.comChina 4825 56
Codow Chemical Co.,Ltd. +86-20-38056109 / 3892 1903+86-20-6261 18462 55
Zhejiang Haiqiang Chemical Co.,Ltd 0571-86050367 0571-86960370 0571-860503870571-86940780info@chinahaiqiangchem.comChina 470 55
Hefei TNJ Chemical Industry Co.,Ltd. +86 (551) 65418684 65418696+86 (551) 65418697info@tnjchem.comChina 1943 62
Shanghai Aladdin Bio-Chem Technology Co.,LTD 021-20337333/400-620-6333021-50323701sale@aladdin-e.comChina 28587 65
Nanjing Search Biotech Co., Ltd +86-25-85860978,81682922,13515111588, 176 68
Shanghai Uteam Biotechnology Co., Ltd. 400-0909-005 021-69955236-807021-69955236-807lj80414@hotmail.comChina 396 55
J & K SCIENTIFIC LTD. 400-666-7788;market6@jkchemical.comChina 96832 76
77-86-1(Tris Base)Related Search:
N,N-Dimethyl-1,4-phenylenediamine ALTRENOGEST Lithium bis(trimethylsilyl)amide 4,4'-Methylenedianiline Tris(hydroxymethyl)nitromethane Tris Base TROMETAMOL HYDROCHLORIDE Betaine Glycine 2-METHYL-1,3-PROPANEDIOL 1,1,1-Tris(hydroxymethyl)ethane 1,3-Propanediol methylol cellulose 2,2-Bis(hydroxymethyl)-2,2',2''-nitrilotriethanol 2-Hydroxyethyl methacrylate 3-Amino-1,2-propanediol BUFFER SOLUTION PH = 6,00 (20 °C) (POTASSIUM DIHYDROGEN PHOSPHATE/SODIUM HYDROXIDE) Hydroxymethyl
1,1,1-tris(hydroxymethyl)-methanamin 1,1,1-tris(hydroxymethyl)-methylamin 1,1,1-tris(hydroxymethyl)methylamine 1,3-Propanediol,2-amino-2-(hydroxymethyl)- 2-amino-2-(hydroxymethyl)-3-propanediol 2-Amino-2-hydroxymethylpropanediol 2-Amino-2-methylol-1,3-propanediol 3-Propanediol,2-amino-2-(hydroxymethyl)-1 Addex-Tham Amino-2-(hydroxymethyl)-1,3-propanediol Aminotrimethylolmethane Aminotris(hydroxymethyl)methane Apiroserum Tham Methanamine, 1,1,1-tris(hydroxymethyl)- Methylamine, 1,1,1-tris(hydroxymethyl)- minotri(hydroxymethyl)methane Pehanorm rigmo base riladyl Talatrol Tham-E thamset Tris amino molecular biology grade Tris amino ultra pure standard Tris buffertris-hydroxymethyl-aminomethan tris(bufferingagent) Tris(hydroxymethyl)amino-methan tris(hydroxymethyl)aminomethane(tris) Tris(hydroxymethyl)methanamine Tris, free base tris[bufferingagent] Trisamin trisaminebuffer Trisaminol tris-hydroxymethyl-aminomethan Trispuffer Tris-steril Trizma Trometamole Tromethamin Tromethamine (CTFA) Tromethanmin Tutofusin tris tutofusintris 1.00 g/L TRIS TRISMAT(TM) TRISMAT TRISMAT(R) TRIS(HYDROXYMETHYL)AMINOMETHANE TRIS (HYDROXYMETHYL) AMINOMETHANE, 7-9 TRIS (HYDROXYMETHYL)AMINOMETHANE, BUFFER SUBSTANCE TRIS(HYDROXYMETHYL)METHYLAMINE TRIS, ENDOTOXIN TESTED TRIS[HYDROXYMETHYL] AMINOETHANE TRIS BASE TRIS BUFFER TRIS BUFFER PH 7.5
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