Carbetocin
- CAS No.
- 37025-55-1
- Chemical Name:
- Carbetocin
- Synonyms
- Carbetocin Acetate;Pabal;DeaMino-2-O-Methyltyrosine-1-carbaoxytocin;d(COMOT);Depotocin;Carbansin;Duratocin;Lonactene;CARBETOCIN;Carbetoxin
- CBNumber:
- CB9175745
- Molecular Formula:
- C45H69N11O12S
- Molecular Weight:
- 988.17
- MDL Number:
- MFCD01076600
- MOL File:
- 37025-55-1.mol
Melting point | 140 - 160°C |
---|---|
Boiling point | 1477.9±65.0 °C(Predicted) |
alpha | D -69.0° (c = 0.25 in 1M acetic acid) |
Density | 1.218±0.06 g/cm3(Predicted) |
storage temp. | -15°C |
solubility | DMSO (Slightly), Methanol (Slightly) |
form | powder |
pka | 13.07±0.70(Predicted) |
color | white to beige |
Water Solubility | Soluble to 29.65 mg/ml in water |
Stability | Hygroscopic |
InChIKey | NSTRIRCPWQHTIA-FOILTOEQNA-N |
FDA UNII | 88TWF8015Y |
NCI Drug Dictionary | carbetocin |
ATC code | H01BB03 |
Carbetocin price More Price(30)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | SML0748 | Carbetocin acetate ≥93% (HPLC) | 37025-55-1 | 5mg | $108 | 2024-03-01 | Buy |
Sigma-Aldrich | SML0748 | Carbetocin acetate ≥93% (HPLC) | 37025-55-1 | 25mg | $425 | 2024-03-01 | Buy |
Tocris | 4852 | Carbetocin | 37025-55-1 | 10 | $173 | 2021-12-16 | Buy |
Usbiological | 506367 | Carbetocin | 37025-55-1 | 5mg | $296 | 2021-12-16 | Buy |
TRC | C175925 | Carbetocin | 37025-55-1 | 50mg | $375 | 2021-12-16 | Buy |
Carbetocin Chemical Properties,Uses,Production
Description
Carbetocin is an alternative synthetic oxytocin-receptor agonist available in Canada, the United Kingdom, and other countries,but not the United States. A large multinational randomized noninferiority trial (N=29,645) found that carbetocin was noninferior to oxytocin for prevention of postpartum hemorrhage and need for additional uterotonic agents after vaginal delivery. Carbetocin has a longer duration of action than oxytocin, eliminating the need for prolonged infusion.
Uses
Carbetocin is an obstetric drug used to control postpartum hemorrhaging.
A new synthetic analog of oxytocin, carbetocin, is long acting and also has a rapid onset of action. It is an oxytocin receptor agonist and also stimulates milk let down due to its action on oxytocin receptors of myoepithelial cells.
Definition
ChEBI: Oxytocin in which the hydrogen on the phenolic hydroxy group is substituted by methyl, the amino group on the cysteine residue is substituted by hydrogen, and the sulfur of the cysteine residue is replaced by a methylene group. A synthetic carba-analogue o oxytocin, it is used to control bleeding after giving birth. Like oxytocin, it causes contraction of the uterus.
Biochem/physiol Actions
Carbetocin is a potent agonist of the oxytocin receptor, with improved in vivo stability over oxytocin.
storage
Store at -20°C
Carbetocin Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
AFINE CHEMICALS LIMITED | +86-0571-85134551 | info@afinechem.com | China | 15394 | 58 |
Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | Mandy@hangyubiotech.com | China | 10991 | 58 |
Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618740459177 | sarah@tnjone.com | China | 1143 | 58 |
Shanghai Yunao International Trade Co., Ltd | +8617621705551 | asdf@shanghaihg.cn | China | 265 | 58 |
Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 994 | 58 |
Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 | admin@guyunchem.com | China | 616 | 58 |
Shanghai Affida new material science and technology center | +undefined15081010295 | admin@oudaxin.com | China | 114 | 58 |
Hangzhou Hyper Chemicals Limited | +86-0086-57187702781 +8613675893055 | info@hyper-chem.com | China | 295 | 58 |
hebei hongtan Biotechnology Co., Ltd | +86-86-1913198-3935 +8617331935328 | sales03@chemcn.cn | China | 973 | 58 |
Alpha Biopharmaceuticals Co., Ltd | +86-15542445688 | sales@alabiochem.com | China | 884 | 58 |
View Lastest Price from Carbetocin manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-09-24 | Carbetocin
37025-55-1
|
US $30.00 / box | 1box | 98% | 2000kg | hebei hongtan Biotechnology Co., Ltd | ||
2024-09-18 | Carbetocin
37025-55-1
|
US $0.00 / g | 1g | 99% | 10kg/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
2024-09-11 | Carbetocin
37025-55-1
|
US $0.00-0.00 / box | 1box | 99 | 50000KG/month | Shanghai Affida new material science and technology center |
- Carbetocin
37025-55-1
- US $30.00 / box
- 98%
- hebei hongtan Biotechnology Co., Ltd
- Carbetocin
37025-55-1
- US $0.00 / g
- 99%
- WUHAN FORTUNA CHEMICAL CO., LTD
- Carbetocin
37025-55-1
- US $0.00-0.00 / box
- 99
- Shanghai Affida new material science and technology center