ChemicalBook >> CAS DataBase List >>3-Methyl-2-nitrobenzoic acid

3-Methyl-2-nitrobenzoic acid

CAS No.
5437-38-7
Chemical Name:
3-Methyl-2-nitrobenzoic acid
Synonyms
2-NITRO-M-TOLUIC ACID;2-NITRO-3-METHYLBENZOIC ACID;BL-ME-0;3-Methyl-2-n;Fluralaner-028;RSYY(Apremilast)-19;3-Methyl-2-nitrobenz;-2-nitrobenzoic acid;Fluralaner Impurity 49;3-Methyl-2-nitrobenzoic
CBNumber:
CB9223457
Molecular Formula:
C8H7NO4
Molecular Weight:
181.15
MDL Number:
MFCD00007180
MOL File:
5437-38-7.mol
MSDS File:
SDS
Last updated:2023-12-25 17:47:29

3-Methyl-2-nitrobenzoic acid Properties

Melting point 220-223 °C (lit.)
Boiling point 314.24°C (rough estimate)
Density 1.4283 (rough estimate)
refractive index 1.5468 (estimate)
storage temp. Sealed in dry,Room Temperature
form powder to crystal
pka 2.26±0.10(Predicted)
color White to Almost white
Water Solubility <0.1 g/100 mL at 22 ºC
BRN 1960698
InChI InChI=1S/C8H7NO4/c1-5-3-2-4-6(8(10)11)7(5)9(12)13/h2-4H,1H3,(H,10,11)
InChIKey DGDAVTPQCQXLGU-UHFFFAOYSA-N
SMILES C(O)(=O)C1=CC=CC(C)=C1[N+]([O-])=O
CAS DataBase Reference 5437-38-7(CAS DataBase Reference)
FDA UNII 61WOP984AB
EPA Substance Registry System 3-Methyl-2-nitrobenzoic acid (5437-38-7)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi,Xn
Risk Statements  36/37/38-20/21/22
Safety Statements  26-36-36/37/39-22-37
WGK Germany  3
TSCA  Yes
HS Code  29163990
NFPA 704
1
2 0

3-Methyl-2-nitrobenzoic acid price More Price(32)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich M60406 3-Methyl-2-nitrobenzoic acid 98% 5437-38-7 25g $30.5 2023-06-20 Buy
Sigma-Aldrich M60406 3-Methyl-2-nitrobenzoic acid 98% 5437-38-7 100g $64 2023-06-20 Buy
TCI Chemical M1370 3-Methyl-2-nitrobenzoic Acid >98.0%(T) 5437-38-7 25g $63 2024-03-01 Buy
TCI Chemical M1370 3-Methyl-2-nitrobenzoic Acid >98.0%(T) 5437-38-7 250g $316 2024-03-01 Buy
Alfa Aesar B25682 3-Methyl-2-nitrobenzoic acid, 98% 5437-38-7 25g $52.65 2024-03-01 Buy
Product number Packaging Price Buy
M60406 25g $30.5 Buy
M60406 100g $64 Buy
M1370 25g $63 Buy
M1370 250g $316 Buy
B25682 25g $52.65 Buy

3-Methyl-2-nitrobenzoic acid Chemical Properties,Uses,Production

Chemical Properties

white to slightly yellow crystalline powder

Uses

2-Nitro-m-toluic Acid, is a building block used for the synthesis of various compounds. It can be used for the synthesis of novel Indolin-2-one derivatives as protein tyrosine phosphatase 1B inhibitors.

General Description

Prisms or white crystalline solid.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

3-Methyl-2-nitrobenzoic acid is a nitrated carboxylic acid. Carboxylic acids donate hydrogen ions if a base is present to accept them. They react in this way with all bases, both organic (for example, the amines) and inorganic. Their reactions with bases, called "neutralizations", are accompanied by the evolution of substantial amounts of heat. Neutralization between an acid and a base produces water plus a salt. Carboxylic acids with six or fewer carbon atoms are freely or moderately soluble in water; those with more than six carbons are slightly soluble in water. Soluble carboxylic acid dissociate to an extent in water to yield hydrogen ions. The pH of solutions of carboxylic acids is therefore less than 7.0. Many insoluble carboxylic acids react rapidly with aqueous solutions containing a chemical base and dissolve as the neutralization generates a soluble salt. Carboxylic acids in aqueous solution and liquid or molten carboxylic acids can react with active metals to form gaseous hydrogen and a metal salt. Such reactions occur in principle for solid carboxylic acids as well, but are slow if the solid acid remains dry.

Fire Hazard

Information concerning the flash point of 3-Methyl-2-nitrobenzoic acid is not available. 3-Methyl-2-nitrobenzoic acid is probably combustible.

Purification Methods

Recrystallise it from EtOH. The methyl ester has m 74o (from MeOH), and the amide [60310-07-8] M 180.1, has m 192o (needles from H2O, prisms from EtOH). [Beilstein 9 H 480, 9 IV 1722.]

Global( 476)Suppliers
Supplier Tel Email Country ProdList Advantage
Baynoe Chem (Suzhou) Co., Ltd.
+86-512 65869404 +86-18934593683 sales06@baynoe.com China 292 58
Henan Fengda Chemical Co., Ltd
+8613613820652 info@fdachem.com China 4685 58
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Dalian Richfortune Chemicals Co., Ltd
0411-84820922 8613904096939 sales@richfortunechem.com China 302 57
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60
Anhui Royal Chemical Co., Ltd.
+86-25-86655873 +8613962173137 marketing@royal-chem.com China 535 55
Yancheng Green Chemicals Co.,Ltd
+undefined-86-25-86655873 info@royal-chem.com China 114 58
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29919 58
Wuhan Boyuan Import & Export Co., LTD
+86-15175982296 15175982296; Mike@whby-chem.com China 983 58
HaBo Hong Kong Co., Limited.
+86-25-18512596065 info@habotech.com CHINA 933 58

View Lastest Price from 3-Methyl-2-nitrobenzoic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-Methyl-2-nitrobenzoic acid pictures 2024-03-19 3-Methyl-2-nitrobenzoic acid
5437-38-7
US $20.93 / Kg/Drum 25Kg/Drum 99.50%HPLC 60tons/month Asia Chem I and E (Jiangsu) Co Ltd
3-Methyl-2-nitrobenzoic acid pictures 2024-03-18 3-Methyl-2-nitrobenzoic acid
5437-38-7
US $0.00 / Kg/Bag 25KG 98% 200tons Yancheng Green Chemicals Co.,Ltd
3-Methyl-2-nitrobenzoic acid pictures 2024-01-08 3-Methyl-2-nitrobenzoic acid
5437-38-7
US $7.00 / KG 1KG 99% 50000tons Wuhan Boyuan Import & Export Co., LTD
3-METHYL-2-NITROBENZOIC ACID 3-Methyl-2-NitrobenzoicAcid98% 3-Methyl-2-Nitrobenzoic Acid 98% 3-Methyl-2-nitrobenzoic 3-Methyl-2-nitrobenz 3-Methyl-2-nitrobenzoic acid, 98% 25GR 3-METHY-2-NITROBENZOICACID m-Toluic acid, 2-nitro- 2-Nitro-m-toluic acid, 3-Carboxy-2-nitrotoluene Benzoic acid, 3-methyl-2-nitro- BL-ME-0 3-Methyl-2-n 3-Methyl-2-nitrobenzoicAcid> -2-nitrobenzoic acid 3-Methyl-2-nitrobenzoic acid ISO 9001:2015 REACH 3-Methyl-2-nitrobenzoic acid /Benzoic acid Fluralaner-028 2-NITRO-3-METHYLBENZOIC ACID 2-NITRO-M-TOLUIC ACID RSYY(Apremilast)-19 Fluralaner Impurity 49 5437-38-7 CH3NO2C6H3COOH C8 Carbonyl Compounds Carboxylic Acids Organic Building Blocks CARBOXYLIC ACID Building Blocks Building Blocks C8 Carbonyl Compounds Carboxylic Acids Chemical Synthesis Organic Building Blocks Benzoic acid Organic acids FINE Chemical & INTERMEDIATES Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts