MORPHINIUM CHLORIDE
- CAS No.
- 52-26-6
- Chemical Name:
- MORPHINIUM CHLORIDE
- Synonyms
- MORPHINE HYDROCHLORIDE;Oramorph SR;ampek;M.O.S.;AN-631;M-Eslon;Epimore;Epimorph;Prepenon;Morphitec
- CBNumber:
- CB9440142
- Molecular Formula:
- C17H20ClNO3
- Molecular Weight:
- 321.8
- MDL Number:
- MFCD00133542
- MOL File:
- 52-26-6.mol
| Melting point | about 200° (dec) |
|---|---|
| alpha | D25 -113.5° (c = 2.2 in H2O, anhydr basis) |
| storage temp. | −20°C |
| solubility | Soluble in water, slightly soluble in ethanol (96 per cent), practically insoluble in toluene. |
| form | Powder |
| Water Solubility | Soluble to 50 mM in water |
| EWG's Food Scores | 1 |
| FDA UNII | J28GE0ROVX |
| NCI Drug Dictionary | Oramorph SR |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H336-H302 |
| Precautionary statements | P264-P270-P301+P312-P330-P501-P261-P271-P304+P340-P312-P403+P233-P405-P501 |
| Hazard Codes | F,T |
| Risk Statements | 11-23/24/25-39/23/24/25 |
| Safety Statements | 7-16-24-33-36/37-45 |
| RIDADR | UN 1230 3/PG 2 |
| WGK Germany | 1 |
| Toxicity | LD50 in mice (mg/kg): 226-318 i.v. (Buchwald, Eadie) |
MORPHINIUM CHLORIDE Chemical Properties,Uses,Production
Chemical Properties
White or almost white, crystalline powder or colourless, silky needles or cubical masses, efflorescent in a dry atmosphere.
Uses
Opioid receptor agonist; analgesic.
Definition
ChEBI: The hydrochloride salt of morphine.
Contact allergens
Morphine bitartrate caused contact dermatitis in a worker at a plant producing opium alkaloids. Morphine hydrochloride and morphine bitartrate showed patchtest- positive reactions in another patient with contact dermatitis working in the production of concentrated poppy straw. We observed a concomitant reaction between a morphine base and a codeine base in a patient with drug skin eruption due to codeine.
Safety Profile
Poison by ingestion, intraperitoneal, intravenous, parenteral, and subcutaneous routes. An experimental teratogen. Experimental reproductive effects. Abuse leads to habituation or addiction. When heated to decomposition it emits very toxic fumes of NOx and HCl.
storage
Store at RT
MORPHINIUM CHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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