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ketene

CAS No.
463-51-4
Chemical Name:
ketene
Synonyms
Keten;ethenone;carbometene;Ethen-1-one;Carbomethene;ketene ISO 9001:2015 REACH
CBNumber:
CB9934768
Molecular Formula:
C2H2O
Molecular Weight:
42.04
MDL Number:
MOL File:
463-51-4.mol
MSDS File:
SDS
Last updated:2024-03-14 15:18:33

ketene Properties

Melting point -150°
Boiling point bp -56°
Density 0.6600
refractive index 1.3040 (estimate)
form Gas
Exposure limits TLV-TWA 0.9 mg/m3 (0.5 ppm); STEL 3.0 mg/m3 (1.5 ppm) (ACGIH); IDLH 50 ppm (NIOSH).
FDA UNII LEP3SM032A
EPA Substance Registry System Ketene (463-51-4)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS02,GHS05,GHS06
Signal word  Danger
Hazard statements  H315-H220-H330-H335-H318
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P280-P305+P351+P338-P310-P260-P271-P284-P304+P340-P310-P320-P403+P233-P405-P501-P210-P377-P381-P403
RIDADR  1955
HazardClass  2.3
IDLA 5 ppm

ketene Chemical Properties,Uses,Production

Description

Ketene is a flammable, colorless gas with asharp, disagreeable odor. Molecular weight = 42.04;Boiling point = 054.4℃; Freezing/Melting point =-148.3℃; Relative vapor density (air = 1): 1.45; Vaporpressure = <1 atm. Hazard Identification (based on NFPA-704 M Rating System): Health 4, Flammability 2,Reactivity 3. Reacts with water.

Chemical Properties

Colorless gas with a sharp penetrating odor;liquefies at -56°C (-68.8°F); solidifies at-151°C (-239.8°F); soluble in alcohol andacetone, decomposed by water.

Uses

For the conversion of higher acids into their anhydrides; for acetylation in the manufacture of cellulose acetate and aspirin.

Uses

Organic chemical syntheses; conversion of higher acids into their anhydrides; for acetylation in the manufacture of cellulose acetate and aspirin

Uses

Ketene is used as an acetylating agent inthe production of cellulose acetate, aspirin,acetic anhydride, and in various organicsyntheses.

Production Methods

Ketene may be prepared also by pyrolysis of acetic anhydride or phenyl acetate or diketene. Other sources are quite unsatisfactory from a standpoint of yield. Small quantities may be made conveniently by heating acetone in a “ketene lamp.” This is a glass apparatus containing a Nichrome filament, heated electrically to red heat. Larger amounts are made by passing acetone or acetic acid through a tube at 700 °C. A very brief contact time is required, so that much of the acetone is undecomposed and has to be condensed and recycled. Also, it is imperative that the reaction tube be of inert material such as porcelain, glass, quartz, copper or stainless steel. A copper tube, if used, should be protected from oxidation by an iron sheath. Inert packing may be used (glass, vanadium pentoxide, porcelain), but just as good yields are obtained with empty tubes. No catalyst is known which accelerates this decomposition at significantly lower temperatures.

Definition

ChEBI: Ethenone is a ketene.

Health Hazard

Ketene is a highly toxic gas. It causes severeirritation to the eyes, nose, throat, and skin.Exposure to 10–15 ppm for several minutescan injure the respiratory tract. It causespulmonary edema. A 30-minute exposure to23 ppm was lethal to mice and a 10-minuteexposure to 200 and 750 ppm caused deathto monkeys and cats.

Fire Hazard

Ketene in its gaseous state should be flammable and explosive in air. The pure compound, however, polymerizes readily and cannot be stored as a gas. Its flash point and LEL and UEL values are not reported. It can react violently with oxidizers and many organic compounds. Its small size and the olefinic unsaturation impart further reactivity to the molecule.

Potential Exposure

Ketene is used as an acetylating agentin cellulose acetate and aspirin manufacture; it is used inthe conversion of higher acids to their anhydrides; inthe production of spices, acetic anhydride, diethylaminogestrinone; ethyl acetate; ethyl acetoacetate; sorbic acid;vitamin A.

First aid

If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit.Medical observation is recommended for 24-48 h afterbreathing overexposure, as pulmonary edema may bedelayed. As first aid for pulmonary edema, a doctor orauthorized paramedic may consider administering a corticosteroid spray.

storage

Ketene cannot be stored. Ketene must be keptaway from water and a wide variety of organic compounds,since violent reactions occur. Ketene must be kept in tightlyclosed containers in a cool, well-ventilated area away fromheat. Metal containers involving the transfer of this chemical should be grounded and bonded. Use only nonsparkingtools and equipment, especially when opening and closingcontainers of this chemical. Sources of ignition, such assmoking and open flames, are prohibited where this chemical is used, handled, or stored in a manner that could createa potential fire or explosion hazard. Wherever this chemicalis used, handled, manufactured, or stored, use explosionproof electrical equipment and fittings. Procedures for thehandling, use, and storage of cylinders should be in compliance with OSHA 1910.101 and 1910.169, as with therecommendations of the Compressed Gas Association.

Shipping

Ketene is not shipped as a rule, but is generated atthe point of use in a chemical process by acetone pyrolysis.It polymerizes readily and hence immediate use is preferred.

Purification Methods

Ketene is prepared by pyrolysis of acetic anhydride. Purify it by passing through a trap at -75o and collecting in a liquid-nitrogen-cooled trap. Ethylene is removed by evacuating the ethylene in an isopentane-liquid-nitrogen slush pack at -160o. Store it at room temperature in a suitable container in the dark or better at -80o, but do not store it under pressure as it may EXPLODE. It is a strong IRRITANT when inhaled and is as poisonous as phosgene. See diketene in “Heterocyclic Compounds”, Chapter 4. [Hurd Org Synth Coll Vol I 330 1941, Andreades & Carlson Org Synth Coll Vol V 679 1973.]

Incompatibilities

Forms an explosive mixture with air.Ketene readily polymerizes. Decomposes in water, alcohol,and ammonia. Reacts with water to form acetic acid.Contact with hydrogen peroxide forms explosive diacetylperoxide. Reacts violently with reducing agents, oxidizers,and many organic compounds. Can dimerize to diketeneeven at low temperatures. Diketene forms an explosive mixture with air.

64-17-5
463-51-4
75-07-0
64-19-7
141-78-6
Synthesis of ketene from Ethanol
Global( 11)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21703 55
Shaanxi Dideu Medichem Co. Ltd
+86-029-81148696 +8615536356810 1047@dideu.com China 3984 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1026@dideu.com China 29831 58
Chizhou Kailong Import and Export Trade Co., Ltd. xg01_gj@163.com China 9503 50
QUALITY CONTROL SOLUTIONS LTD. 15920483169 ORDERS@QCSRM.COM China 18736 58
Hebei Dueling International Trade Co. LTD 18032116176 399549586@qq.com China 1181 58
Shandong Jiuyue Biological Technology Co., LTD 15553348166 m15553348166@163.com China 3462 58

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View Lastest Price from ketene manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
ketene pictures 2020-01-01 ketene
463-51-4
US $0.10 / KG 1KG 99.0% 1000 tons Shaanxi Dideu Medichem Co. Ltd
  • ketene pictures
  • ketene
    463-51-4
  • US $0.10 / KG
  • 99.0%
  • Shaanxi Dideu Medichem Co. Ltd
Carbomethene ethenone Keten Ethen-1-one carbometene ketene ISO 9001:2015 REACH 463-51-4 H2CCO CH2CO C2H2O