4-ニトロキノリンN-オキシド 化学特性,用途語,生産方法
外観
黄色～赤みの黄色, 結晶～結晶性粉末
溶解性
水に難溶。エタノール, アセトンに易溶。エタノールに溶け、水に難溶。
化学的特性
yellow-brown crystals or powder
使用
4-Nitroquinoline N-Oxide is used in method for constructing animal model of oral mucosal malignancy related to Kras mutation.
定義
ChEBI: A quinoline N-oxide carrying a nitro substituent at position 4.
一般的な説明
Yellowish-brown plates or needles or yellow solid.
空気と水の反応
4-NITROQUINOLINE N-OXIDE is hygroscopic and light sensitive. Insoluble in water.
反応プロフィール
4-NITROQUINOLINE N-OXIDE reacts with strong oxidizing agents.
健康ハザード
ACUTE/CHRONIC HAZARDS: 4-NITROQUINOLINE N-OXIDE may cause irritation. When heated to decomposition it may emit toxic fumes of carbon monoxide, carbon dioxide and nitrogen oxides.
火災危険
Flash point data for 4-NITROQUINOLINE N-OXIDE are not available; however, 4-NITROQUINOLINE N-OXIDE is probably combustible.
安全性プロファイル
Suspected carcinogen
with experimental carcinogenic, neoplas tigenic,
and tumorigenic data. Poison by
intraperitoneal and subcutaneous routes. An experimental teratogen. Other experimental
reproductive effects. Human mutation data
reported. When heated to decomposition it
emits toxic fumes of NOx.
純化方法
The N-oxide recrystallises from aqueous acetone as yellow needles or platelets. [Ochiai J Org Chem 18 534 1953, Seki et al. J Phys Chem 91 126 1987, Beilstein 20 III/IV 3396.]
4-ニトロキノリンN-オキシド 上流と下流の製品情報
原材料
準備製品