1-ドデカノール 化学特性,用途語,生産方法
外観
白色/無色～ほとんど白色/ほとんど無色粉末～塊～透明液体
定義
本品は、ヤシ油(*)から得られる脂肪酸を還元して得た脂肪族アルコールである。参照表示名称：ヤシ油
解説
1-ドデカノール，無色，特異臭のある直鎖の飽和一価アルコール。融点23.5℃，沸点153.5℃(25mmHg)，比重d420＝0.8330，屈折率nD20＝1.4428(過冷却下)。水に難溶，エチルアルコール，エーテルに可溶。
株式会社平凡社 世界大百科事典 第２版について 情報
用途
アルコール,合成樹脂滑剤,合成洗剤原料,安定剤,可塑剤,香粧品香料の溶剤,食品香料
用途
可塑剤、洗剤、化粧品原料
化粧品の成分用途
エモリエント剤、非水系増粘剤、起泡剤、親水性増粘剤、乳化安定剤、香料
物理的性質
1-Dodecanol is a white low melting crystalline solid that has a melting point of 24°C.The air odor threshold for dodecyl alcohol (isomer not specified) is reported to be 7.1 ppb.
化学的特性
Lauryl alcohol has a characteristic fatty odor; unpleasant at high concentrations, but delicate and floral on dilution. 1-Dodecanol is a saturated 12-carbon fatty alcohol obtained from coconut oil fatty acids. It has a fatty, waxy flavor and is used in detergents, lubricating oils, and pharmaceuticals.
天然物の起源
Reported found in the oil of Mexican lime and in the oil from flowers of Furcraea gigantean. Also reported
found in apple, banana, sour cherry, citrus peel oils, melon, pineapple, potato, thymus, cheeses, butter, milk powder, chicken and beef
fat, cooked pork, beer, whiskies, white wine, peanuts, beans, mushrooms, mango, coriander seed and leaf, rice, Bourbon vanilla,
endive, crab, clam, Cape gooseberry, pawpaw and maté.
使用
1-Dodecanol is used in chemical formulations for a variety of purposes, including as an emulsion stabilizer, a skin-conditioning emollient, and a viscosity-increasing agent.
製造方法
Commercially 1-Dodecanol may be prepared by hydrogenation of lauric acid; normally employed as a replacement for the corresponding aldehyde.
定義
ChEBI: 1-Dodecanol is a fatty alcohol that is dodecane in which a hydrogen from one of the methyl groups is replaced by a hydroxy group. It is registered for use in apple and pear orchards as a Lepidopteran pheromone/sex attractant, used to disrupt the mating behaviour of certa n moths whose larvae destroy crops.
調製方法
1-Dodecanol is produced commercially by the oxo process
and from ethylene by the Ziegler process, which involves
oxidation of trialkylaluminum compounds. It can also be
produced by sodium reduction or high-pressure hydrogenation
of esters of naturally occurring lauric acid.
一般的な説明
Colorless thick liquid with a sweet odor. Floats on water. Freezing point is 75°F.
反応プロフィール
Dodecyl alcohol is an alcohol. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert them to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides.
健康ハザード
Liquid will cause burning of the eyes and may irritate skin.
安全性プロファイル
Moderately toxic by
intraperitoneal route. Mildly toxic by ingestion. A
severe human skin irritant. Questionable
carcinogen with experimental tumorigenic data.
Combustible when exposed to heat or flame; can
react with oxidizing materials. To fight fire, use dry
chemical, CO2. When heated to decomposition it
emits acrid smoke and irritating fumes
発がん性
1-Dodecanol showed weak tumor-promoting activity when applied three times a week
for 60 weeks to the skin of mice that had previously received
an initiating dose of dimethylbenz[a]anthracene. Papillomas
developed in 2 of 30 mice after 39 and 49 weeks of treatment.
純化方法
Crystallise dodecanol from aqueous EtOH, and distil it through a spinning-band column under vacuum. [Ford & Marvel Org Synth 10 62 1930, Beilstein 1 IV 1844.]
1-ドデカノール 上流と下流の製品情報
原材料
準備製品