グルカゴン様ペプチド 1 (7-37)

グルカゴン様ペプチド 1 (7-37) 化学構造式
106612-94-6
CAS番号.
106612-94-6
化学名:
グルカゴン様ペプチド 1 (7-37)
别名:
グルカゴン様ペプチド 1 (7-37);グルカゴン様ペプチドI (7-37);グルカゴン様ペプチド1フラグメント 7-37, ヒト
英語名:
GLP-1 (7-37)
英語别名:
Tglp-1;GLP-1, 7-37;HuMan GLP-1;Glp-I (7-37);insulinotropin;GLP-1(7-37), >98%;Human GLP-1 (7-37);GLP-1 acetate salt;GLP-1 (7-37) (HUMAN);GLP-1(7-37) impurity
CBNumber:
CB1445727
化学式:
C151H228N40O47
分子量:
3355.67
MOL File:
106612-94-6.mol

グルカゴン様ペプチド 1 (7-37) 物理性質

比重(密度) :
1.48±0.1 g/cm3(Predicted)
貯蔵温度 :
−20°C
溶解性:
Water:30.0(Max Conc. mg/mL);8.34(Max Conc. mM)
外見 :
Lyophilized powder
水溶解度 :
2mg/mlで水に溶ける
シーケンス:
H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly-OH
CAS データベース:
106612-94-6

安全性情報

Sフレーズ  22-24/25
WGK Germany  3

グルカゴン様ペプチド 1 (7-37) 価格 もっと(8)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01BCS4034865
GLP-1 (7-37) (human, bovine, guinea pig, mouse, rat), H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly-
106612-94-6 1mg ¥79000 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01BCS4034865
GLP-1 (7-37) (human, bovine, guinea pig, mouse, rat), H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly-
106612-94-6 5mg ¥315000 2024-03-01 購入
Sigma-Aldrich Japan G9416 グルカゴン様ペプチド1フラグメント 7-37, ヒト ≥96% (HPLC)
Glucagon-Like Peptide 1 Fragment 7-37 human ≥96% (HPLC)
106612-94-6 0.5mg ¥128000 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01LKTG4482 グルカゴン様ペプチドI (7-37)
Glucagon-like Peptide I (7-37)
106612-94-6 0.5mg ¥51400 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01LKTG4482 グルカゴン様ペプチドI (7-37)
Glucagon-like Peptide I (7-37)
106612-94-6 1mg ¥90900 2024-03-01 購入

グルカゴン様ペプチド 1 (7-37) 化学特性,用途語,生産方法

説明

GLP-1 (7-37) is an endogenous truncated form of GLP-1 that arises from proglucagon processing in intestinal endocrine L cells, GLP-1 (7-37) acts as a GLP-1 receptor agonist and is an insulinotropic hormone that augments glucose induced insulin secretion. GLP-1 (7-37) and derivatives GLP-1 (9-37) and GLP-1 (28-37) can reduce plaque inflammation and increase phenotypic characteristics of plaque stability in a murine model of atherosclerosis.

使用

Glucagon-Like Peptide 1 Fragment 7-37 human has been used:
  • as a positive control for insulin secretion of pancreatic islets
  • to test its effect on insulin response in horse islets
  • in combination with mesenchymal stem cells (MSCs) test its protective effects in myocardial infarction

一般的な説明

Glucagon-Like Peptide 1 Fragment 7-37 human (GLP-1-(7-37)) is an amino-truncated form of GLP-1.

Biochem/physiol Actions

Glucagon-Like Peptide 1 Fragment 7-37 human (GLP-1-(7-37)) interacts with the GLP-1 receptor (GLP-1r). It mediates insulin release by stimulating the cyclic AMP accumulation in islet cells GLP-l(7-37) is a potential therapeutic agent due to its insulin-secretagogue functionality.

グルカゴン様ペプチド 1 (7-37) 上流と下流の製品情報

原材料

準備製品


グルカゴン様ペプチド 1 (7-37) 生産企業

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106612-94-6(グルカゴン様ペプチド 1 (7-37))キーワード:


  • 106612-94-6
  • Insulinotropin (human)
  • Peptide GLP-1 (human glucose-lowering peptide-1)
  • Glp-I (7-37)
  • Glucagon like peptide I (7-37)
  • Glucagon-related peptide (oncorhynchus kisutch), 3-L-glutamic acid-6-L-phenylalanine-9-L-aspartic acid-12-L-serine-15-L-glutamic acid-16-glycine-21-L-isoleucine-24-L-alanine-27-L-valine-28-L-lysine-31-glycine-
  • Tglp-1
  • GLP-1, 7-37
  • Preproglucagon 78-108
  • GLP-1 (7-37) (huMan, bovine, guinea pig, Mouse, rat) Proglucagon (78-108) (huMan, bovine, guinea pig, Mouse, rat), Insulinotropin (huMan, bovine, guinea pig, Mouse, rat), Glucagon-Like Peptide 1 (7-37) (huMan, bovine, guinea pig, Mouse, rat), Preproglucag
  • 7-37-Glucagon-like peptide I (human)
  • Human GLP-1 (7-37)
  • insulinotropin
  • GLP-1, 7-37, Preproglucagon 78-108
  • Proglucagon (78-108) (huMan, bovine, guinea pig, Mouse, rat), Insulinotropin (huMan, bovine, guinea pig, Mouse, rat), Glucagon-Like Peptide 1 (7-37) (huMan, bovine, guinea pig, Mouse, rat), Preproglucagon (98-128) (huMan, bovine, guinea pig, Mouse, rat)
  • Proglucagon (78-108) (huMan, bovine, guinea pig, Mouse, rat), Glucagon-Like Peptide 1 (7-37) (huMan, bovine, guinea pig, Mouse, rat), Insulinotropin (huMan, bovine, guinea pig, Mouse, rat), Preproglucagon (98-128) (huMan, bovine, guinea pig, Mouse, rat)
  • HuMan GLP-1
  • 7-37-Glucagon-likepeptide
  • H-His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-Gly-OH acetate salt
  • GLP-1 (7-37) Acetate | Glucagon-Like Peptide 1
  • l-L-lysyl-L-α-glutamyl-L-phenylalanyl-L-isoleucyl-L-alany
  • PROGLUCAGON (78-108) (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT)
  • PREPROGLUCAGON 78-108 HUMAN
  • PREPROGLUCAGON (98-128) (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT)
  • INSULINOTROPIN (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT)
  • HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-ILE-ALA-TRP-LEU-VAL-LYS-GLY-ARG-GLY
  • H-HIS-ALA-GLU-GLY-THR-PHE-THR-SER-ASP-VAL-SER-SER-TYR-LEU-GLU-GLY-GLN-ALA-ALA-LYS-GLU-PHE-ILE-ALA-TRP-LEU-VAL-LYS-GLY-ARG-GLY-OH
  • HAEGTFTSDVSSYLEGQAAKEFIAWLVKGRG
  • GLP-1 (HUMAN, 7-37) (BOVINE, CANINE, RAT, GUINEA PIG)
  • GLP-1 (7-37) (HUMAN)
  • GLP-1 (7-37) (HUMAN, BOVINE, GUINEA PIG, MOUSE, RAT)
  • グルカゴン様ペプチド 1 (7-37)
  • グルカゴン様ペプチドI (7-37)
  • グルカゴン様ペプチド1フラグメント 7-37, ヒト
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