SR 2595

 化学構造式
1415252-61-7
CAS番号.
1415252-61-7
化学名:
别名:
英語名:
SR 2595
英語别名:
SR 2595;SR2595 >=98% (HPLC);4'-[[5-[[[(1S)-1-[4-(1,1-dimethylethyl)phenyl]ethyl]amino]carbonyl]-2,3-dimethyl-1H-indol-1-yl]methyl]-[1,1'-biphenyl]-2-carboxylicacid;[1,1'-Biphenyl]-2-carboxylic acid, 4'-[[5-[[[(1S)-1-[4-(1,1-dimethylethyl)phenyl]ethyl]amino]carbonyl]-2,3-dimethyl-1H-indol-1-yl]methyl]-
CBNumber:
CB14666849
化学式:
C37H38N2O3
分子量:
558.71
MOL File:
1415252-61-7.mol

SR 2595 物理性質

沸点 :
785.4±60.0 °C(Predicted)
比重(密度) :
1.13±0.1 g/cm3(Predicted)
貯蔵温度 :
Store at -20°C
溶解性:
≤5mg/ml in ethanol;10mg/ml in DMSO;10mg/ml in dimethyl formamide
外見 :
crystalline solid
酸解離定数(Pka):
3.87±0.36(Predicted)

安全性情報

SR 2595 価格

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入

SR 2595 化学特性,用途語,生産方法

説明

SR 2595 is an inverse agonist of PPARγ (IC50 = 30 nM) that represses both transactivation in a promoter:reporter assay and expression of the adipogenic marker fatty acid-binding protein 4 in differentiating murine preadipocytes. Repression of PPARγ with SR 2595 promotes osteogenesis, as measured by calcium phosphatase deposition, in cultured human mesenchymal stem cells (MSCs). SR 2595 also increases expression of bone morphogenetic proteins BMP2 and BMP6 in MSCs.

SR 2595 上流と下流の製品情報

原材料

準備製品


SR 2595 生産企業

Global( 20)Suppliers
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BOC Sciences 16314854226
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ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
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Energy Chemical 021-58432009 400-005-6266
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MedBioPharmaceutical Technology Inc 021-69568360 18916172912
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TargetMol Chemicals Inc. 4008200310
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Hubei Aiputi Bioengineering Co., Ltd. 17762444226
d17762444226@163.com China 2402 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627
customer_service@efebio.com China 8740 58
ApexBio Technology --
sales@apexbt.com United States 6254 58

  • 1415252-61-7
  • SR 2595
  • SR2595 >=98% (HPLC)
  • [1,1'-Biphenyl]-2-carboxylic acid, 4'-[[5-[[[(1S)-1-[4-(1,1-dimethylethyl)phenyl]ethyl]amino]carbonyl]-2,3-dimethyl-1H-indol-1-yl]methyl]-
  • 4'-[[5-[[[(1S)-1-[4-(1,1-dimethylethyl)phenyl]ethyl]amino]carbonyl]-2,3-dimethyl-1H-indol-1-yl]methyl]-[1,1'-biphenyl]-2-carboxylicacid
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