ウリジン-5′-二りん酸二ナトリウム
ウリジン-5′-二りん酸二ナトリウム 物理性質
- 貯蔵温度 :
- -20°C
- 外見 :
- 粉
- 色:
- ホワイトからオフホワイト
- 水溶解度 :
- 水にわずかに溶ける。
- Sensitive :
- Moisture Sensitive
- BRN :
- 8817400
- InChIKey:
- KWDGQJWFEYTPBN-IBOJMDDDSA-L
- SMILES:
- O[C@@H]1[C@@H]([C@@H](COP(O)(=O)OP(O)(O)=O)O[C@H]1N1C=CC(=O)NC1=O)O.[NaH] |&1:1,2,3,15,r|
- CAS データベース:
- 27821-45-0(CAS DataBase Reference)
ウリジン-5′-二りん酸二ナトリウム 価格
もっと(7)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01COBSS-0107 |
ウリジン5'-二りん酸二ナトリウム塩
Uridine 5'-diphosphoric acid disodium salt |
27821-45-0 |
1g |
￥10000 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01COBSS-0107 |
ウリジン5'-二りん酸二ナトリウム塩
Uridine 5'-diphosphoric acid disodium salt |
27821-45-0 |
5g |
￥27500 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
94330 |
ウリジン 5′-二リン酸 二ナトリウム塩 水和物 ≥96.0% (HPLC)
Uridine 5′-diphosphate disodium salt hydrate ≥96.0% (HPLC) |
27821-45-0 |
100mg |
￥27100 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
94330 |
ウリジン 5′-二リン酸 二ナトリウム塩 水和物 ≥96.0% (HPLC)
Uridine 5′-diphosphate disodium salt hydrate ≥96.0% (HPLC) |
27821-45-0 |
500mg |
￥102000 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01TOC3111 |
UDP二ナトリウム塩
UDP disodium salt |
27821-45-0 |
50mg |
￥22000 |
2024-03-01 |
購入 |
ウリジン-5′-二りん酸二ナトリウム 化学特性,用途語,生産方法
外観
白色, 結晶性粉末〜粉末
用途
調味料、医薬品の中間原料。薬理研究ツール。
使用
Uridine-5'-diphosphate disodium salt (UDP-Na2) is an organometallic compound, It is a P2Y6 receptor agonist and GPR105 receptor inhibitor. It is used in studies on nucleic acid (RNA) biosynthesis and cell signaling. UDP is a nucleotide that upon phosphorylation to UTP becomes a substrate for enzymes such as RNA polymerase(s) and GTPases. These enzymes are involved in a wide range of applications from the synthesis of RNA to the regulation of G-coupled Protein Receptors (GPCR) and cell signaling molecules such as Rho-signaling via Guanine Nucleotide Exchange Factors (GEF).
主な応用
Uridine 5′-diphosphate disodium salt hydrate has been used:
as a standard for quantification of metabolite levels in murine tumor interstitial fluid by liquid chromatography-mass spectrometry (LC/MS)
as a UDP standard for nucleotide analysis by liquid chromatography-high resolution mass spectrometry (LC-HRMS)
to treat E6.5 retina explants in vitro, to study its effect on the entry and elongation of microglial cells into the embryonic quail retina
純化方法
Crystallise it from MeOH. It may contain some Ba salt(s); hence stir it with Amberlite IR-120 cation exchanger (25mL, wet resin, 15-50 mesh in H+ form) in H2O (50mL) until the nucleotide dissolves. Filter, wash resin with H2O until the eluate is neutral. Combine the filtrate and washings, and adjust the pH to 8.0 with 2.0 M aqueous NaOH. Concentrate it in vacuo to a small volume (~ 20mL), and add Me2CO dropwise until crystallisation begins. Cool to 0o, and the shiny plates of di Na uridine-5’-phosphate dihydrate are filtered off and dried over P2O5 at 25o/0.1mm for 24hours (>76% recovery). UV: max at 262nm ( 10,000 M-1cm -1) in 0.1 M HCl. [Boon et al. J Chem Soc 408 1950, Smith Biochemical Preparations 8 130 1960.] [Beilstein 24 IV 1214.]
ウリジン-5′-二りん酸二ナトリウム 上流と下流の製品情報
原材料
準備製品
ウリジン-5′-二りん酸二ナトリウム 生産企業
Global( 339)Suppliers
ウリジン-5′-二りん酸二ナトリウム スペクトルデータ(13CNMR)
27821-45-0(ウリジン-5′-二りん酸二ナトリウム)キーワード:
- 27821-45-0
- UDP 2NA
- URIDINE 5'-DIPHOSPHATE DISODIUM SALT
- URIDINE 5'-DIPHOSPHORIC ACID DISODIUM SALT
- Uridine 5'-(trihydrogen diphosphate), disodium salt
- UDP(URIDINE-5''-DIPHOSPHATE)
- URIDINE-5''- DIPHOSPHATE, DISODIUM SALT(UDP.NA2)
- URIDINE-5''-DIPHOSPHATE DISODIUM SALT HYDRATE (UDP)
- URIDINE 5''- DIPHOSPHATE DISODIUM SALT (5''-UDP-NA2)
- Uriidine-5'-diphosphate, disodium salt
- Uridine-5'-diphosphoglucose disodium salt
- Einecs 248-678-9
- 5′-UDP,2Na
- UDP.Na2
- SodiuM 1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxyMethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyriMidin-5-yl hydrogendiphosphate
- -2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl hydrogendiphosphate
- Sodium 1-((2R,3R,4S,5R)
- Uridine 5'-diphosphate disodiu salt
- Diquafosol Impurity 2(UDP Sodium Salt)
- 5'-UDP 2Na Hydrate
- Uridine 5'-diphosphate disodium salt hydrate, ≥96.0% (HPLC)
- Uridine-5'-diphosphoglucose disodium salt (UDP)
- Uridine 5'-diphosphate disodium salt hyd
- ridine 5'-diphosphate disodium salt
- Uridine 5'-(trihydrogen diphosphate), sodium salt (1:2)
- Uridine 5'-diphosphoric acid disodium
- Uridine-5-diphosphate disodium
- Uridine 5'-diphosphate Disodium Salt Monohydrate
- Uridine -5- disodium diphosphate
- sodium ((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl hydrogen diphosphate
- 5'-UDP-Na2
- ウリジン5'-二りん酸水素二ナトリウム
- ウリジン-5′-二りん酸二ナトリウム
- ウリジン5'-二リン酸二ナトリウム水和物
- ウリジン5'-二りん酸二ナトリウム塩
- UDP二ナトリウム塩
- ウリジン5'-二りん酸二ナトリウム
- ウリジン5′-二りん酸水素二ナトリウム