Chinese english Germany Korea

N-(5-アミノ-1-オキソペンチル)-L-Phe-L-Phe-L-Pro-N-メチル-L-Leu-L-Met-NH2

N-(5-アミノ-1-オキソペンチル)-L-Phe-L-Phe-L-Pro-N-メチル-L-Leu-L-Met-NH2 化学構造式
133156-06-6
CAS番号.
133156-06-6
化学名:
N-(5-アミノ-1-オキソペンチル)-L-Phe-L-Phe-L-Pro-N-メチル-L-Leu-L-Met-NH2
别名:
N-(5-アミノ-1-オキソペンチル)-L-Phe-L-Phe-L-Pro-N-メチル-L-Leu-L-Met-NH2;5-アミノバレリル-L-Phe-L-Phe-L-Pro-N-メチル-L-Leu-L-Met-NH2;5-アミノペンタノイル-L-Phe-L-Phe-L-Pro-N-メチル-L-Leu-L-Met-NH2;GR-73632;(2S)-2-{1-[(2S)-1-[(2S)-2-[(2S)-2-(5-アミノペンタンアミド)-3-フェニルプロパンアミド]-3-フェニルプロパノイル]ピロリジン-2-イル]-N-メチルホルムアミド}-N-[(1S)-1-カルバモイル-3-(メチルスルファニル)プロピル]-4-メチルペンタンアミド
英語名:
DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2
英語别名:
GR 73632;GR-73632 (GR73632);H2H-(CH2)4-CO-PHE-PRO-NME-LEU-MET-NH2;d-AMinovaleryl-Phe-Phe-Pro-N-Me-Leu-Met-NH2;DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2;d-AMinovaleryl-(Pro9,N-Me-Leu10)-Substance P (7-11);δ-Aminovaleryl-(Pro9,N-Me-Leu10)-Substance P (7-11);DELTA-AMINOVALERYL-(PRO9,N-ME-LEU10)-SUBSTANCE P (7-11);(DELTA-AMINOVALERYL6,PRO9,N-ME-LEU10)-SUBSTANCE P (6-11);δ-Aminovaleryl-[Pro9, Leu(N-Me)10]-SubstanceP Fragment 7-11
CBNumber:
CB3126730
化学式:
C40H59N7O6S
分子量:
766
MOL File:
133156-06-6.mol
MSDS File:
SDS

N-(5-アミノ-1-オキソペンチル)-L-Phe-L-Phe-L-Pro-N-メチル-L-Leu-L-Met-NH2 物理性質

沸点 :
1082.2±65.0 °C(Predicted)
比重(密度) :
1.198±0.06 g/cm3(Predicted)
貯蔵温度 :
-20°C
溶解性:
Water:1.0(Max Conc. mg/mL);1.31(Max Conc. mM)
外見 :
Powder
酸解離定数(Pka):
13.34±0.46(Predicted)
水溶解度 :
Soluble to 1 mg/ml in water

安全性情報

Sフレーズ  22-24/25
WGK Germany  3

N-(5-アミノ-1-オキソペンチル)-L-Phe-L-Phe-L-Pro-N-メチル-L-Leu-L-Met-NH2 価格 もっと(3)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01TOC1669
GR 73632 		133156-06-6 1mg ￥128000 2024-03-01 購入
Sigma-Aldrich Japan G114 >97%
GR 73632 >97%		 133156-06-6 1mg ￥142000 2021-03-23 購入
Sigma-Aldrich Japan G114 >97%
GR 73632 >97%		 133156-06-6 5mg ￥536200 2018-12-25 購入

N-(5-アミノ-1-オキソペンチル)-L-Phe-L-Phe-L-Pro-N-メチル-L-Leu-L-Met-NH2 化学特性,用途語,生産方法

使用

GR 73632 is a NK1 tachykinin receptor agonist used in the treatment of asthma and gastrointestinal disorders. It is involved in the contraction of muscles.

一般的な説明

Neurokinin (NK) receptors are acted upon by tachykinins or neurokinins namely, NKA and NKB. These are endogenous ligands. An exogenous agonist/ligand for NK1 is GR 64349 petpide.

Biochem/physiol Actions

GR 73632 interacts with neurokinin (NK1) receptor, which results in rhythmic tapping of hind-foot in gerbils. Administration of this peptide in the intra-ventral tegmental area (VTA) results in locomotor activity. It interacts with and activates NK1 receptors present on smooth muscle and interstitial cells of Cajal, resulting in elevated distention-induced peristalsis.

N-(5-アミノ-1-オキソペンチル)-L-Phe-L-Phe-L-Pro-N-メチル-L-Leu-L-Met-NH2 上流と下流の製品情報

原材料

準備製品

N-(5-アミノ-1-オキソペンチル)-L-Phe-L-Phe-L-Pro-N-メチル-L-Leu-L-Met-NH2 生産企業

Global( 50)Suppliers
名前 電話番号 電子メール 国籍 製品カタログ 優位度
Career Henan Chemica Co 		+86-0371-86658258 15093356674;
 laboratory@coreychem.com China 30255 58
BOC Sciences 		16314854226; +16314854226
 inquiry@bocsci.com United States 19743 58
Chengdu Youngshe Chemical Co., Ltd. 		+8618108235634
 Cecilia@youngshechem.com China 2345 58
Amadis Chemical Company Limited 		571-89925085
sales@amadischem.com China 131980 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
 3bsc@sina.com China 15848 69
Chemsky（shanghai）International Co.,Ltd. 021-50135380
shchemsky@sina.com China 32344 50
Sigma-Aldrich 021-61415566 800-8193336
 orderCN@merckgroup.com China 51471 80
Nanjing Leon Biological Technology Co., Ltd. 17705183659
 sales@njleonbiotech.com China 5503 55
Nanjing Peptide Biotech Ltd. 025-025-58361106-805-805 13082558573
 liugang@njpeptide.com China 9962 55
Hangzhou Peptidego Biotech Co.,Ltd. 0571-87213919
eric@peptidego.com China 6527 58

133156-06-6(N-(5-アミノ-1-オキソペンチル)-L-Phe-L-Phe-L-Pro-N-メチル-L-Leu-L-Met-NH2)キーワード:

N-(5-アミノ-1-オキソペンチル)-L-Phe-L-Phe-L-Pro-N-メチル-L-Leu-L-Met-NH2 N〜2〜,N〜2〜-DIMETHYL-1,2-PENTANEDIAMINE
  • 133156-06-6
  • δ-Aminovaleryl-[Pro9, Leu(N-Me)10]-SubstanceP Fragment 7-11
  • N-(5-Amino-1-oxopentyl)-L-Phe-L-Phe-L-Pro-N-methyl-L-Leu-L-Met-NH2
  • (2S)-1-[(2S)-2-[[(2S)-2-(5-aminopentanoylamino)-3-phenyl-propanoyl]amino]-3-phenyl-propanoyl]-N-[(1S)-1-[[(1S)-1-carbamoyl-3-(methylthio)propyl]carbamoyl]-3-methyl-butyl]-N-methyl-pyrrolidine-2-carboxamide
  • (2S)-N-[(2S)-1-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-1-[(2S)-2-[[(2S)-2-(5-aminopentanoylamino)-3-phenylpropanoyl]amino]-3-phenylpropanoyl]-N-methylpyrrolidine-2-carboxamide
  • (2S)-N-[(2S)-1-[[(2S)-1-azanyl-4-methylsulfanyl-1-oxo-butan-2-yl]amino]-4-methyl-1-oxo-pentan-2-yl]-1-[(2S)-2-[[(2S)-2-(5-azanylpentanoylamino)-3-phenyl-propanoyl]amino]-3-phenyl-propanoyl]-N-methyl-pyrrolidine-2-carboxamide
  • d-AMinovaleryl-(Pro9,N-Me-Leu10)-Substance P (7-11)
  • d-AMinovaleryl-Phe-Phe-Pro-N-Me-Leu-Met-NH2
  • GR 73632
  • H2H-(CH2)4-CO-PHE-PRO-NME-LEU-MET-NH2
  • (DELTA-AMINOVALERYL6,PRO9,N-ME-LEU10)-SUBSTANCE P (6-11)
  • DELTA-AMINOVALERYL-PHE-PHE-PRO-N-ME-LEU-MET-NH2
  • DELTA-AMINOVALERYL-(PRO9,N-ME-LEU10)-SUBSTANCE P (7-11)
  • L-Methioninamide,N-(5-amino-1-oxopentyl)-L-phenylalanyl-L-phenylalanyl-L-prolyl-N-methyl-L-leucyl-
  • GR-73632 (GR73632)
  • δ-Aminovaleryl-(Pro9,N-Me-Leu10)-Substance P (7-11)
  • Neurokinin Receptor,NK receptor,Tachykinin receptor,GR73632,inhibit,Inhibitor,GR-73632,GR 73632
  • N-(5-アミノ-1-オキソペンチル)-L-Phe-L-Phe-L-Pro-N-メチル-L-Leu-L-Met-NH2
  • 5-アミノバレリル-L-Phe-L-Phe-L-Pro-N-メチル-L-Leu-L-Met-NH2
  • 5-アミノペンタノイル-L-Phe-L-Phe-L-Pro-N-メチル-L-Leu-L-Met-NH2
  • GR-73632
  • (2S)-2-{1-[(2S)-1-[(2S)-2-[(2S)-2-(5-アミノペンタンアミド)-3-フェニルプロパンアミド]-3-フェニルプロパノイル]ピロリジン-2-イル]-N-メチルホルムアミド}-N-[(1S)-1-カルバモイル-3-(メチルスルファニル)プロピル]-4-メチルペンタンアミド
Copyright 2017 © ChemicalBook. All rights reserved