4-メトキシインドール
4-メトキシインドール 物理性質
- 融点 :
- 69-70 °C (lit.)
- 沸点 :
- 181-183 °C/24 mmHg (lit.)
- 比重(密度) :
- 1.1135 (rough estimate)
- 屈折率 :
- 1.5310 (estimate)
- 闪点 :
- 181-183°C/24mm
- 貯蔵温度 :
- Keep in dark place,Inert atmosphere,Room temperature
- 溶解性:
- エタノール:可溶50mg/mL、透明、微黄色
- 外見 :
- 結晶性粉末および/またはチャンク
- 酸解離定数(Pka):
- 17.22±0.30(Predicted)
- 色:
- 白い
- Sensitive :
- Light Sensitive
- BRN :
- 122456
- InChIKey:
- LUNOXNMCFPFPMO-UHFFFAOYSA-N
- LogP:
- 2.060 (est)
- CAS データベース:
- 4837-90-5(CAS DataBase Reference)
- NISTの化学物質情報:
- 1H-Indole, 4-methoxy-(4837-90-5)
4-メトキシインドール 価格
もっと(21)
メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
富士フイルム和光純薬株式会社(wako)
|
W01APOOR4545 |
4-メトキシ-1H-インドール
4-Methoxy-1H-indole |
4837-90-5 |
1g |
¥7700 |
2024-03-01 |
購入 |
富士フイルム和光純薬株式会社(wako)
|
W01APOOR4545 |
4-メトキシ-1H-インドール
4-Methoxy-1H-indole |
4837-90-5 |
5g |
¥18200 |
2024-03-01 |
購入 |
東京化成工業
|
M1250 |
4-メトキシインドール >98.0%(GC)
4-Methoxyindole
>98.0%(GC) |
4837-90-5 |
1g |
¥6300 |
2024-03-01 |
購入 |
東京化成工業
|
M1250 |
4-メトキシインドール >98.0%(GC)
4-Methoxyindole
>98.0%(GC) |
4837-90-5 |
5g |
¥21600 |
2024-03-01 |
購入 |
関東化学株式会社(KANTO)
|
25813-52 |
4‐メトキシインドール >98.0%(HLC)
4‐Methoxyindole >98.0%(HLC) |
4837-90-5 |
5g |
¥14500 |
2024-03-01 |
購入 |
4-メトキシインドール 化学特性,用途語,生産方法
外観
白色~黄褐色、結晶性粉末~粉末
用途
有機合成原料。
化学的特性
light brown to grey crystalline powder
使用
4-Methoxyindole is a reactant for alpha-ethyltryptamines as dual dopamine-serotonin releasers.
Synthesis Reference(s)
Journal of Heterocyclic Chemistry, 24, p. 1499, 1987
DOI: 10.1002/jhet.5570240602
合成
Step1 :1-[(E)-2-(2-methoxy-6-nitrophenyl)vinyl]pyrrolidine: To a solution of 10 g of 1-methoxy-2-methy3-nitrobenzene in 100 ml of DMF are added 8.74 ml of N,N-dimethylformamide dimethyl acetal and 5.44 ml of pyrrolidine, and the mixture is then refluxed for 3 hours. The mixture is concentrated to half its volume under vacuum, the remaining mixture is poured into ether/water and extracted with ether, the organic phase is washed with saturated NaCl solution and dried over MgSO4 , and the solvent is evaporated off under vacuum. 1-[(E)-2-(2-methoxy-6-nitrophenyl)vinyl]pyrrolidine; yield 14.6 g.
Stpe 2 : synthesis of 4-Methoxyindole, A suspension of 150 ml of zinc powder in 500 ml of 0.5N HCl is stirred for 1 hour at room temperature. The suspension is ded by suction, washed with water to neutral pH, with anhydrous EtOH and then with ether, and dried. To a solution of 10 g of the compound from the preceding step in 46 ml of acetic acid are added, portionwise, 31.6 g of activated zinc, while keeping the temperature between 20 and 30°C using an ice bath. The reaction mixture is stirred at room temperature for 30 minutes, and is filtered. The filtrate is extracted with EtOAc, the organic phase is washed with NaHCO3 solution and with saturated NaCl solution, and dried over MgSO4 , and the solvent is evaporated off under vacuum. The residue is chromatographed on silica gel, eluting with a cyclohexane/EtOAc mixture in a gradient of from (98/2 v/v) to (95/5 v/v). 4-Methoxy- 1H-indole; yield 1.6 g.
4-メトキシインドール 上流と下流の製品情報
原材料
準備製品
4-メトキシインドール 生産企業
Global( 360)Suppliers
4-メトキシインドール スペクトルデータ(1HNMR、13CNMR、IR1、IR2、MS、Raman)
4837-90-5(4-メトキシインドール)キーワード:
- 4837-90-5
- 4-METHOXYLINDOLE
- 4-METHOXYINDOLE
- AKOS JY2082619
- Methoxyindole,98%
- 4-Methoxyindole,99%
- 4-METHOXYLINDOLE 98%
- 4-METHOXYINDOLE 98+%
- 4-methoxy-1H-indole(SALTDATA: FREE)
- 1H-Indole, 4-Methoxy-
- 4-Methoxy-1H-indole 98%
- 4-Methoxyindole 99%
- 4-Methoxy-1H-indole98%
- 4-methoxy-1H-indole, 4-methoxy-indole, methoxy-1H-indole, 4-methoxy indole, 4-methoxylindole, 5-methoxylindole, 4-methoxyindole
- 1H-INDOL-4-YL METHYL ETHER
- Indole, 4-methoxy-
- 4-Methoxyindole>
- TIANFUCHEM-4-Methoxyindole
- 4-Methoxyindole in stock Factory
- 4-Methoxyindole, 98%, for synthesis
- 4-METHOXY-1H-INDOLE
- 4-メトキシインドール
- 4-メトキシ-1H-インドール
- 4‐メトキシインドール
- インドール
- 構造分類