4-Methoxyindole
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4-Methoxyindole 속성
- 녹는점
- 69-70 °C (lit.)
- 끓는 점
- 181-183 °C/24 mmHg (lit.)
- 밀도
- 1.1135 (rough estimate)
- 굴절률
- 1.5310 (estimate)
- 인화점
- 181-183°C/24mm
- 저장 조건
- Keep in dark place,Inert atmosphere,Room temperature
- 용해도
- 에탄올: 용해성50mg/mL, 투명, 희미한 노란색
- 물리적 상태
- 결정질 분말 및/또는 덩어리
- 산도 계수 (pKa)
- 17.22±0.30(Predicted)
- 색상
- 하얀색
- 감도
- Light Sensitive
- BRN
- 122456
- InChIKey
- LUNOXNMCFPFPMO-UHFFFAOYSA-N
- LogP
- 2.060 (est)
- CAS 데이터베이스
- 4837-90-5(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xi | ||
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위험 카페고리 넘버 | 36/37/38 | ||
안전지침서 | 26-36-24/25 | ||
WGK 독일 | 3 | ||
위험 참고 사항 | Irritant/Keep Cold | ||
위험 등급 | KEEP COLD, LIGHT SENSITIVE | ||
HS 번호 | 29339900 |
4-Methoxyindole C화학적 특성, 용도, 생산
화학적 성질
light brown to grey crystalline powder용도
4-Methoxyindole is a reactant for alpha-ethyltryptamines as dual dopamine-serotonin releasers.Synthesis Reference(s)
Journal of Heterocyclic Chemistry, 24, p. 1499, 1987 DOI: 10.1002/jhet.5570240602Synthesis
Step1 :1-[(E)-2-(2-methoxy-6-nitrophenyl)vinyl]pyrrolidine: To a solution of 10 g of 1-methoxy-2-methy3-nitrobenzene in 100 ml of DMF are added 8.74 ml of N,N-dimethylformamide dimethyl acetal and 5.44 ml of pyrrolidine, and the mixture is then refluxed for 3 hours. The mixture is concentrated to half its volume under vacuum, the remaining mixture is poured into ether/water and extracted with ether, the organic phase is washed with saturated NaCl solution and dried over MgSO4 , and the solvent is evaporated off under vacuum. 1-[(E)-2-(2-methoxy-6-nitrophenyl)vinyl]pyrrolidine; yield 14.6 g.Stpe 2 : synthesis of 4-Methoxyindole, A suspension of 150 ml of zinc powder in 500 ml of 0.5N HCl is stirred for 1 hour at room temperature. The suspension is ded by suction, washed with water to neutral pH, with anhydrous EtOH and then with ether, and dried. To a solution of 10 g of the compound from the preceding step in 46 ml of acetic acid are added, portionwise, 31.6 g of activated zinc, while keeping the temperature between 20 and 30°C using an ice bath. The reaction mixture is stirred at room temperature for 30 minutes, and is filtered. The filtrate is extracted with EtOAc, the organic phase is washed with NaHCO3 solution and with saturated NaCl solution, and dried over MgSO4 , and the solvent is evaporated off under vacuum. The residue is chromatographed on silica gel, eluting with a cyclohexane/EtOAc mixture in a gradient of from (98/2 v/v) to (95/5 v/v). 4-Methoxy- 1H-indole; yield 1.6 g.
4-Methoxyindole 준비 용품 및 원자재
원자재
준비 용품
4-Methoxyindole 공급 업체
글로벌( 360)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
AS WATER CO., LTD. | +86-18994963526 +8618994963526 |
1346073549@qq.com | United Kingdom | 176 | 58 |
Henan Bao Enluo International TradeCo.,LTD | +86-17331933971 +86-17331933971 |
deasea125996@gmail.com | China | 2503 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21691 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32480 | 60 |
career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
Zhejiang ZETian Fine Chemicals Co. LTD | 18957127338 |
stella@zetchem.com | China | 2141 | 58 |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 |
admin@nexconn.com | China | 10248 | 58 |
HaBo Hong Kong Co., Limited. | +86-25-18512596065 |
info@habotech.com | CHINA | 933 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
4-Methoxyindole 관련 검색:
아니졸 트리플르오르메톡시벤젠 4-메톡시페닐초산 아니스알데히드 P-아니시딘 메톡시벤질클로라이드 핀도롤 5-(트리플루오로메톡시)이사틴
3-(METHOXYMETHOXY)BENZALDEHYDE
4-Methoxyphenylacetone
6-METHOXYINDOLE 99%
4-Acetoxyindole
4-Benzyloxyindole
4-Benzyloxyindole-3-carboxaldehyde
3-Formyl-4-methoxyindole,4-methoxyindole-3-aldehyde
METHYL 4-METHOXY-2-INDOLECARBOXYLATE
Methoxyindole 99% indol-5-yl methyl ether,5-METHOXYINDOLE REPANIDAL
4-Methoxy-1H-indole-2-carboxylic acid