우르소데옥시콜산
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우르소데옥시콜산 속성
- 녹는점
- 203-204 °C (lit.)
- 끓는 점
- 437.26°C (rough estimate)
- 알파
- 60 º (c=2, EtOH)
- 밀도
- 0.9985 (rough estimate)
- 굴절률
- 60.5 ° (C=2, EtOH)
- 인화점
- 9℃
- 저장 조건
- 2-8°C
- 용해도
- 에탄올: 50mg/mL, 투명
- 산도 계수 (pKa)
- pKa 5.04±0.04(H2O t = 25.0±0.1 I = 0.00)(Approximate)
- 물리적 상태
- 단단한. 가루.
- 색상
- 흰색 - 거의 흰색입니다.
- 수용성
- 실질적으로 불용성
- Merck
- 14,9889
- BRN
- 3219888
- InChIKey
- RUDATBOHQWOJDD-UZVSRGJWSA-N
- LogP
- 3-3.38 at 20℃
- CAS 데이터베이스
- 128-13-2(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xi | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 36/37/38 | ||
| 안전지침서 | 24/25-36-26 | ||
| 유엔번호(UN No.) | UN1230 - class 3 - PG 2 - Methanol, solution | ||
| WGK 독일 | 2 | ||
| RTECS 번호 | FZ2000000 | ||
| F 고인화성물질 | 10 | ||
| HS 번호 | 29181990 | ||
| 독성 | LD50 in mice (g/kg): 0.1 i.v. (Ardenne, Reitnauer); in rats, mice (mg/kg): 2000, 6000 s.c.; 1000, 1200 i.p., 310, 260 i.v. (Ward) |
우르소데옥시콜산 C화학적 특성, 용도, 생산
화학적 성질
WHITE CRYSTALLINE POWDER용도
Ursodeoxycholic acid (UDCS) is a cell protectant used extensively to mitigate hepatic and biliary diseases. Ursodeoxycholic acid may be used to study its specific activities that range from reduction of cholesterol absorpition, cholesterol gallstone dissolution to suppression of immune response. It is also used as an anticholelithogenic. Epimer with Chenodiol with respect to the hydroxyl group at C7.정의
ChEBI: Ursodeoxycholic acid is a bile acid found in the bile of bears (Ursidae) as a conjugate with taurine. Used therapeutically, it prevents the synthesis and absorption of cholesterol and can lead to the dissolution of gallstones. It has a role as a human metabolite and a mouse metabolite. It is a bile acid, a dihydroxy-5beta-cholanic acid and a C24-steroid. It is a conjugate acid of an ursodeoxycholate.일반 설명
Ursodeoxycholic acid (UDCA) is a secondary bile acid that helps regulate cholesterol. Mass spectrometry-based analysis of UDCA is routinely performed in clinical diagnostic testing applications such as neonatal testing of inborn errors of bile acid synthesis, differentiating among types of familial intrahepatic cholestasis, and therapeutic monitoring of patient responses to UDCA therapy. This Certified Spiking Solution? is suitable as a starting material in preparation of linearity standards, calibrators, and controls for use in LC-MS/MS and GC/MS bile acid testing methods.Purification Methods
Recrystallise ursodiol from wet Et2O, EtOH or EtOH/MeOH. [Iwasaki Hoppe Seyler's Z Physiol Chem 244 181, 183 1936, Beilstein 10 III 1635.]우르소데옥시콜산 준비 용품 및 원자재
원자재
다이에틸렌 글리콜
2,3-부탄디온
세노디올
CHOLIC ACID METHYL ESTER
크롬산 칼륨
메틸알콜
Acetylcholic acid
5Β-CHOLANIC ACID
아세트산(빙초산)
염산
크롬(6+) 트리산화물
나트륨
준비 용품
우르소데옥시콜산 공급 업체
글로벌( 757)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Pharmaceuticals Group Corp., Ltd. | +8613004379774 |
wu@jiaerke.com | China | 33 | 58 |
| Handan Tongyi New Material Technology Co., Ltd | +8617330042575 |
ty003@handantongyi.com | China | 364 | 58 |
| Xinyi Dajiang Chemical Co.,Ltd. | +8617314178111 |
243096958@qq.com | China | 5 | 58 |
| XuZhou Magic Biotechnology Co., Ltd. | +undefined13921770081 |
SVP01@magicbiotech.cn | China | 92 | 58 |
| Wuhan Han Sheng New Material Technology Co.，Ltd | +8617798174412 |
admin01@hsnm.com.cn | China | 2118 | 58 |
| BINBO BIOLOGICAL CO.,LTD | +8618629063126 |
info@binbobiological.com | China | 324 | 58 |
| Sinoway Industrial co., ltd. | 0592-5800732; +8613806035118 |
xie@china-sinoway.com | China | 992 | 58 |
| Hong Kong Excellence Biotechnology Co., Ltd. | +86-86-18838029171 +8618126314766 |
ada@sh-teruiop.com | China | 893 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 |
deasea125996@gmail.com | China | 2503 | 58 |
| Hangzhou ICH Biofarm Co., Ltd | +undefined8613073685410 |
sales@ichemie.com | China | 985 | 58 |
우르소데옥시콜산 관련 검색:
엽산 시트르산 아세트산 스테아르산 염소 산 나트륨 콜산염 우르소데옥시콜산
Hyaluronic acid
Solvent Red 43
Deoxycholic acid
URSODEOXYCHOLIC-2,2,4,4-D4 ACID
Bromothymol Blue
URSODEOXYCHOLIC ACID-24-13C
Ascoric Acid
3-epi-Ursodeoxycholic acid
(+)-NEOMENTHOL
(2R,5S)-5-(5-Fluoro-3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester
(2S)-2-[[[(1,1-Dimethylethyl)diphenylsilyl]oxy]methyl]-1,3-oxathiolan-5-ol 5-Acetate