GF109203X
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GF109203X 속성
- 녹는점
- 280℃ (decomposition)
- 끓는 점
- 685.6±55.0 °C(Predicted)
- 밀도
- 1.30±0.1 g/cm3(Predicted)
- 저장 조건
- 2-8°C
- 용해도
- DMSO: ~1mg/ml
- 물리적 상태
- 액체
- 산도 계수 (pKa)
- 8.13±0.60(Predicted)
- 색상
- 오렌지 레드
- 색상
- 오렌지색
- 수용성
- 물에 불용성.
- 안정성
- 제공된 대로 구매일로부터 2년 동안 안정적입니다. DMSO 용액은 -20°C에서 최대 6개월 동안 보관할 수 있습니다.
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
GF109203X C화학적 특성, 용도, 생산
용도
Bisindolylmaleimide is used as a highly selective inhibitor of all PKC isoforms and slight inhibitor of GSK-3, used to selectively probe for PKC-mediated pathways for transduction of hormone, cytokine, and growth factor signals, very potent and selective inhibitor of protein kinase C.생물학적 활성
Very potent and selective inhibitor of protein kinase C, selective for the α and β 1 isoforms (IC 50 values are 0.0084, 0.0180, 0.210, 0.132, and 5.8 μ M for α , β 1, δ , ε , and ζ isoforms respectively). Selective over MLCK, PKG and PKA (IC 50 values are 0.6, 4.6, and 33 μ M respectively). Potent antagonist at the 5-HT 3 receptor (K i = 29.5 nM). Anti-inflammatory in vivo . Also available as part of the Mixed Kinase Inhibitor Tocriset™ .Biochem/physiol Actions
A potent and selective competitive inhibitor of protein kinase C (PKC) and of glycogen synthase kinase-3 (GSK-3). Inhibits parathyroid hormone-induced Ca2+ resorption from isolated bone tissue, Staurosporine, another protein kinase inhibitor, actually enhanced Ca2+ resorption elicited by a number of agents, but GF109203X counteracted that enhancement.GF109203X 준비 용품 및 원자재
원자재
준비 용품
GF109203X 공급 업체
글로벌( 164)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9341 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32686 | 60 |
Biochempartner | 0086-13720134139 |
candy@biochempartner.com | CHINA | 967 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
career henan chemical co | +86-0371-86658258 15093356674; |
factory@coreychem.com | China | 29826 | 58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 |
sales@hzclap.com | CHINA | 6313 | 58 |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 |
1026@dideu.com | China | 28455 | 58 |
Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 |
shawn@hirisunpharm.com | CHINA | 9923 | 58 |
Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 |
info@dycnchem.com | CHINA | 52867 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 |
sales@sarms4muscle.com | China | 10523 | 58 |
GF109203X 관련 검색:
BISINDOLYLMALEIMIDE IV
BISINDOLYLMALEIMIDE V
GF109203X
BISINDOLYLMALEIMIDE VIII ACETATE SALT
GO 6983
BISINDOLYLMALEIMIDE VII
RHODAMINE-CONJUGATED BISINDOLYLMALEIMIDE INHIBITOR
BISINDOLYLMALEIMIDE II
BISINDOLYLMALEIMIDE VIII ACETATE
BISINDOLYLMALEIMIDE IX, METHANESULFONATE,BISINDOLYLMALEIMIDE IX METHANESULPHONATE SALT
BISINDOLYLMALEIMIDE III
BISINDOLYLMALEIMIDE IX METHANESULFONATE
BISINDOLYLMALEIMIDE III, HYDROCHLORIDE,BISINDOLYLMALEIMIDE III, HYDROCHLORIDE
BISINDOLYLMALEIMIDE XL, HCL,BISINDOLYLMALEIMIDE XI HYDROCHLORIDE,BISINDOLYLMALEIMIDE XI, HCL,BISINDOLYLMALEIMIDE XI HYDROCHLORIDE
Bisindolylmaleimide III, HCl
BISINDOLYLMALEIMIDE III, ACETATE
Bisindolylmaleimide I, HCl
Bisindolylmaleimide Inhibitor Set