칼헥스231

칼헥스231
칼헥스231 구조식 이미지
카스 번호:
652973-93-8
한글명:
칼헥스231
동의어(한글):
칼헥스231
상품명:
Calhex 231
동의어(영문):
Calhex 231;Calhex-231 (Calhex231);Calhex 231 hydrochloride;4-Chloro-N-[(1S,2S)-2-[[(1R)-1-(1-naphthalenyl)ethyl]amino]cyclohexyl]benzamide;Benzamide, 4-chloro-N-[(1S,2S)-2-[[(1R)-1-(1-naphthalenyl)ethyl]amino]cyclohexyl]-;4-Chloro-N-[(1S,2S)-2-[[(1R)-1-(1-naphthalenyl)ethyl]amino]cyclohexyl]-benzamide hydrochloride
CBNumber:
CB21565173
분자식:
C25H27ClN2O
포뮬러 무게:
406.95
MOL 파일:
652973-93-8.mol
MSDS 파일:
SDS

칼헥스231 속성

녹는점
53-55°C
저장 조건
-20°C Freezer
용해도
DMSO: 용해성15mg/mL, 투명
물리적 상태
가루
색상
흰색에서 베이지색
CAS 데이터베이스
652973-93-8

안전

WGK 독일 3

칼헥스231 C화학적 특성, 용도, 생산

화학적 성질

White Solid

용도

Calhex 231 hydrochloride has been used:
  • as a calcium-sensing receptor (CaSR) antagonist: to test its impact on hearing in rats
  • to test its effect on blood pressure levels spontaneous hypertensive rats (SHRs)
  • to test its effect on acoustic response bias in zebrafish
  • in Caco-2 cells to test its effect on, overexpression of fibroblast growth factor-23 (FGF-23 )

Biochem/physiol Actions

Calhex 231 is a negative allosteric modulator of the calcium sensing receptor CaSR. Calhex 231 blocks calcium-induced accumulation of inositol phosphate with an IC50 of 0.36 μM.

칼헥스231 준비 용품 및 원자재

원자재

준비 용품


칼헥스231 공급 업체

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