히스톤아세틸트랜스퍼라제억제제IV,CPTH2
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히스톤아세틸트랜스퍼라제억제제IV,CPTH2 속성
- 녹는점
- 190-191 °C
- 끓는 점
- 460.3±37.0 °C(Predicted)
- 밀도
- 1.38±0.1 g/cm3(Predicted)
- 저장 조건
- 2-8°C
- 용해도
- DMSO에 용해됨
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- 14.57±0.20(Predicted)
- 색상
- 흰색에서 베이지색
- 수용성
- Water: < 0.1 mg/mL (insoluble)
- 감도
- Light Sensitive
- 안정성
- 제공된 대로 구매일로부터 1년 동안 안정적입니다. DMSO의 솔루션은 최대 1개월 동안 -20°에서 보관할 수 있습니다.
안전
| WGK 독일 | nwg |
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히스톤아세틸트랜스퍼라제억제제IV,CPTH2 C화학적 특성, 용도, 생산
용도
CPTH2 is a histone acetyltransferase inhibitor that modulates Gcn5p dependent functional network in vitro and in vivo.일반 설명
CPTH2 ((3-methylcyclopentylidene-[4-(4′-chlorophenyl)thiazol-2-yl]hydrazone)) inhibits histone acetyltransferase functionality and reduces acetylation of histone H3 and H4. CPTH2 promotes apoptosis in lymphoma cell lines. It may serve as an anticancer agent. CPTH2 inhibits α-tubulin acetylation and modulates autophagic pathway in human acute myeloid leukemia cell lines.Biochem/physiol Actions
CPTH2 is a histone acetyltransferase (HAT) inhibitor modulating the Gcn5 network. Histone Acetyltransferase (HAT) inhibitor modulating Gcn5 network. Histone acetyltransferases (HATs) act as transcriptional coactivators. Histone acetylation plays an important role in regulating the chromatin structure and is tightly regulated by two classes of enzyme, histone acetyltransferases (HAT) and histone deacetylases (HDAC). Deregulated HAT and HDAC activity plays a role in the development of a range of cancers. Consequently, inhibitors of these enzymes have potential as anticancer agents.히스톤아세틸트랜스퍼라제억제제IV,CPTH2 준비 용품 및 원자재
원자재
준비 용품
히스톤아세틸트랜스퍼라제억제제IV,CPTH2 공급 업체
글로벌( 73)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32686 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354 |
support@targetmol.com | United States | 19973 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 |
sales@aladdinsci.com | United States | 57511 | 58 |
| Hefei Mokai Pharmaceutical Technology Co., Ltd | 18130062233 |
3362556465@qq.com | China | 8000 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 |
jkinfo@jkchemical.com | China | 96815 | 76 |
| VDM Biochemicals | 0330-2528181 |
sales@vdmbio.com | United States | 510 | 64 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-400-6206333 18521732826 |
market@aladdin-e.com | China | 25014 | 65 |
| TargetMol Chemicals Inc. | 021-021-33632979 15002134094 |
marketing@targetmol.com | China | 7854 | 58 |
| Shanghai TaoSu Biochemical Technology Co., Ltd. | 021-33632979 |
info@tsbiochem.com | China | 8073 | 58 |
| ShangHai KenEn Chemical Technology Co., Ltd. | 13120367189 |
mychess007@163.com | China | 1994 | 55 |